Filtered By:
Source: Journal of Neurochemistry
This page shows you your search results in order of date. This is page number 7.
Order by Relevance | Date
Total 123 results found since Jan 2013.
Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen ‐glucose deprivation
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - December 20, 2016 Category: Neuroscience Authors: Yue Zhang, Gina Hong, Kin Sing Stephen Lee, Bruce D. Hammock, Debebe Gebremedhin, David R. Harder, Raymond C. Koehler, Adam Sapirstein Tags: Original Article Source Type: research
Activation of σ1 and σ2 receptors by afobazole increases glial cell survival and prevents glial cell activation and nitrosative stress after ischemic stroke
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - August 3, 2016 Category: Neuroscience Authors: C. Katnik, A. Garcia, A. A. Behensky, I.E. Yasny, A. M. Shuster, S. B. Seredenin, A. V. Petrov, J. Cuevas Tags: Original Article Source Type: research
Deficiency in the voltage ‐gated proton channel Hv1 increases M2 polarization of microglia and attenuates brain damage from photothrombotic ischemic stroke
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - July 28, 2016 Category: Neuroscience Authors: Dai ‐Shi Tian, Chun‐Yu Li, Chuan Qin, Madhuvika Murugan, Long‐Jun Wu, Jun‐Li Liu Tags: Original Article Source Type: research
Role of serum ‐ and glucocorticoid‐inducible kinases in stroke
Abstract
Increased expression of serum‐ and glucocorticoid‐inducible kinase 1 (SGK1) can be induced by stress and growth factors in mammals, and plays an important role in cancer, diabetes, and hypertension. A recent work suggested that SGK1 activity restores damage in a stroke model. To further investigate the role of SGKs in ischemic brain injury, we examined how SGK inhibitors influence stroke outcome in vivo and neurotoxicity in vitro. Infarct volumes were compared in adult mice with middle cerebral artery occlusion, followed by 24 h reperfusion, in the absence or presence of SGK inhibitors. Neurotoxicity assay,...
Source: Journal of Neurochemistry - May 24, 2016 Category: Neuroscience Authors: Koichi Inoue, Tiandong Leng, Tao Yang, Zhao Zeng, Takatoshi Ueki, Zhi ‐Gang Xiong Tags: Original Article Source Type: research
Role of serum‐ and glucocorticoid‐inducible kinases in stroke
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - April 27, 2016 Category: Neuroscience Authors: Koichi Inoue, Tiandong Leng, Tao Yang, Zhao Zeng, Takatoshi Ueki, Zhi‐Gang Xiong Tags: Original Article Source Type: research
MMP‐9 in translation: from molecule to brain physiology, pathology, and therapy
This article is part of the 60th Anniversary special issue.
MMP‐9, through cleavage of specific target proteins, plays a major role in synaptic plasticity and neuroinflammation, and by those virtues contributes to brain physiology and a host of neurological and psychiatric disorders.
This article is part of the 60th Anniversary special issue.
Source: Journal of Neurochemistry - March 21, 2016 Category: Neuroscience Authors: Behnam Vafadari, Ahmad Salamian, Leszek Kaczmarek Tags: Bench to Bedside Source Type: research
MMP ‐9 in translation: from molecule to brain physiology, pathology, and therapy
This article is part of the 60th Anniversary special issue.
MMP‐9, through cleavage of specific target proteins, plays a major role in synaptic plasticity and neuroinflammation, and by those virtues contributes to brain physiology and a host of neurological and psychiatric disorders.
This article is part of the 60th Anniversary special issue.
Source: Journal of Neurochemistry - March 20, 2016 Category: Neuroscience Authors: Behnam Vafadari, Ahmad Salamian, Leszek Kaczmarek Tags: Bench to Bedside Source Type: research
Sevoflurane Prevents Stroke‐induced Depressive and Anxiety Behaviors by Promoting Cannabinoid Receptor Subtype I‐dependent Interaction Between β‐Arrestin 2 and ERK1/2 in the Rat Hippocampus
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - March 15, 2016 Category: Neuroscience Authors: Houzhong Zhang, Li Li, Yanli Sun, Xingyi Zhang, Yifan Zhang, Shuang Xu, Peng Zhao, Tiecheng Liu Tags: Original Article Source Type: research
cPKCβ‐mediated phosphorylation inhibits CRMP2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke‐induced mice
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - January 20, 2016 Category: Neuroscience Authors: Xuan Yang, Xinxin Zhang, Yun Li, Song Han, David W. Howells, Shujuan Li, Junfa Li Tags: Original Article Source Type: research
Attenuation of cerebral ischemic injury in interferon regulatory factor 3‐deficient rat
In this study, a novel IRF3 knockout rat strain and a transgenic rat strain with neuronal‐specific IRF3 over‐expression (IRF3‐TG) were created. Subsequently, the generated IRF3‐knockout rats, the neuronal‐specific IRF3 over‐expressing rats and their corresponding controls were subjected to transient middle cerebral artery occlusion and followed by reperfusion, to investigate the exact role of IRF3 in cerebral I/R in rats. In contrast to the results in mice, IRF3 deficiency in rats provided significant protection against cerebral I/R injury and inhibited neuronal apoptosis, inflammation, and oxidative stress aft...
Source: Journal of Neurochemistry - December 21, 2015 Category: Neuroscience Authors: Lei Li, Juan‐Juan Qin, Sen Guo, Peng Zhang, Jun Gong, Xiao‐Jing Zhang, Ankang Zheng, Hao Xia, Hongliang Li Tags: Original Article Source Type: research
Plasmatic retinol‐binding protein 4 and glial fibrillary acidic protein as biomarkers to differentiate ischemic stroke and intracerebral hemorrhage
We describe the discovery and subsequent replications of RBP4 and its combination with circulating GFAP as plasmatic biomarkers for hyperacute stroke subtype differentiation. The combination of these biomarkers and others might aid to speed up the discrimination of both stroke subtypes improving the outcome of patients.
A rapid differentiation of ischemic stroke from intracerebral hemorrhage is essential to provide the appropriate treatment. We describe the discovery and subsequent replications of RBP4 and its combination with circulating GFAP as plasmatic biomarkers for hyperacute stroke subtype differentiation. The comb...
Source: Journal of Neurochemistry - December 17, 2015 Category: Neuroscience Authors: Víctor Llombart, Teresa García‐Berrocoso, Alejandro Bustamante, Dolors Giralt, David Rodriguez‐Luna, Marian Muchada, Anna Penalba, Cristina Boada, Mar Hernández‐Guillamon, Joan Montaner Tags: Original Article Source Type: research
Attenuation of Cerebral Ischemic Injury in Interferon Regulatory Factor 3 Deficient Rat
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - November 30, 2015 Category: Neuroscience Authors: Lei Li, Juan‐Juan Qin, Sen Guo, Peng Zhang, Jun Gong, Xiao‐Jing Zhang, Ankang Zheng, Hao Xia, Hongliang Li Tags: Original Article Source Type: research
IL‐1alpha induces angiogenesis in brain endothelial cells in vitro: implications for brain angiogenesis after acute injury
In conclusion, our data highlights a potential new role for IL‐1 in brain repair mechanisms and identifies IL‐1α as a potential new therapy to promote post‐stroke angiogenesis.
Inflammation is a major contributor to neuronal injury and is associated with poor outcome after neurotrauma. We demonstrate that cytokine IL‐1α is chronically elevated in the brain after experimental stroke suggesting that it is present chronically post‐stroke. We demonstrate that IL‐1α is a potent mediator of endothelial activation and inducer of angiogenic markers in endothelial cells. Our data highlights a new role for IL‐1 in ...
Source: Journal of Neurochemistry - November 27, 2015 Category: Neuroscience Authors: Kathleen Salmeron, Takuma Aihara, Elena Redondo‐Castro, Emmanuel Pinteaux, Gregory Bix Tags: Original Article Source Type: research
IL‐1alpha induces angiogenesis in brain endothelial cells in vitro: implications for brain angiogenesis after acute injury
In conclusion, our data highlights a potential new role for IL‐1 in brain repair mechanisms and identifies IL‐1α as a potential new therapy to promote post‐stroke angiogenesis.
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - November 6, 2015 Category: Neuroscience Authors: Kathleen Salmeron, Takuma Aihara, Elena Redondo‐Castro, Emmanuel Pinteaux, Gregory Bix Tags: Original Article Source Type: research
Plasmatic RBP4 and GFAP as biomarkers to differentiate ischemic stroke and intracerebral hemorrhage
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - November 3, 2015 Category: Neuroscience Authors: Víctor Llombart, Teresa García‐Berrocoso, Alejandro Bustamante, Dolors Giralt, David Rodriguez‐Luna, Marian Muchada, Anna Penalba, Cristina Boada, Mar Hernández‐Guillamon, Joan Montaner Tags: Original Article Source Type: research
