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Source: UCLA Newsroom: Health Sciences

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Total 132 results found since Jan 2013.

Many take anticoagulants and OTC supplements, which poses risk
FINDINGSNearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban also used  over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding. People taking these medications largely lacked knowledge of some potentially serious interactions.BACKGROUNDDirect-acting oral anticoagulants are the drug of choice for stroke prevention in patients with atrial fibrillation, which occurs most frequently in older patients. Apixaban is one of the most frequently prescribed. However, most people prescribed apix...
Source: UCLA Newsroom: Health Sciences - October 31, 2019 Category: Universities & Medical Training Source Type: news

How our brains create breathing rhythm is unique to every breath
Breathing propels everything we do, so its rhythm must be carefully organized by our brain cells, right?Wrong.Every breath we take arises from a disorderly group of neurons — each one like a soloist belting out its song before it unites with other neurons to harmonize on a fresh breath.That ’s the gist ofa UCLA study published March 3 in the online edition of  Neuron.“We were surprised to learn that how our brain cells work together to generate breathing rhythm is different every time we take a breath,” saidJack Feldman, the study ’s senior author, a professor of neurobiology at the David Geffen School of Medic...
Source: UCLA Newsroom: Health Sciences - March 4, 2020 Category: Universities & Medical Training Source Type: news

New study pinpoints how the brain ’s inner clock measures seconds
FINDINGSUCLA neuroscientistsstudying how the brain measures time in secondsintroduced mice to two different scents. The mice learned that one odor predicted the arrival of a sweet liquid reward after three seconds, while the other predicted the reward after six seconds.The mice started licking the spout earlier in anticipation of the reward after they sniffed the first scent than when they smelled the second.While the mice responded to the two stimuli, researchers observed activity intwo regions of their brains: the striatum and the premotor cortex,which provides input to the striatum. They found that while both regions en...
Source: UCLA Newsroom: Health Sciences - September 23, 2020 Category: Universities & Medical Training Source Type: news

Election stress can hurt your heart
Election stress is in full effect, and it can take a heavy toll on our heart health. Stressful situations produce a surge of hormones in our bodies that can elevate our blood pressure and heart rate and speed up our breathing.“This reaction is the normal way the body prepares to deal with a stressful situation,” said Dr. Megan Kamath, a cardiologist at UCLA Health. “However, these symptoms should not be ignored, as stress ineven a healthy person can cause significant damage to one ’s health.”In terms of triggering stress or exacerbating preexisting heart conditions, the election is on par with other traumatic epi...
Source: UCLA Newsroom: Health Sciences - November 2, 2020 Category: Universities & Medical Training Source Type: news

Differences in human, mouse brain cells have important implications for disease research
FINDINGSA UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders. A lack of oxygen triggers molecular repair mechanisms in these mouse astrocytes but not in human astrocytes. In contrast, inflammation activates immune-response genes in human astrocytes but not mouse astrocytes.BACKGROUNDAlthough the mouse is a ubiquitous laboratory model used in research for neurological diseases, results from studies in mice are not always applicable to humans. In fact, more t...
Source: UCLA Newsroom: Health Sciences - June 25, 2021 Category: Universities & Medical Training Source Type: news

UCLA raises $611 million in 2020 –21, supporting students and advancing critical research
UCLA raised more than $611 million in gifts and pledges in the fiscal year ending June 30, exceeding its annual goal and drawing donors from all 50 states and 72 countries.“Generous donors at all levels have continued to partner with UCLA to effect meaningful change on campus, in the community and around the world,” said Chancellor Gene Block. “Despite a challenging year, our friends have once again demonstrated their extraordinary commitment to UCLA’s mission of education, research and service.”In response to conditions created by the COVID-19 pandemic, many donors focused on students ’ need to adapt to distan...
Source: UCLA Newsroom: Health Sciences - October 4, 2021 Category: Universities & Medical Training Source Type: news

Concussions and kids: Project co-led by UCLA gets $10 million grant from NIH
A research project co-led by theUCLA Steve Tisch BrainSPORT Programaimed at improving the assessment and treatment of concussions in school-aged children has been awarded $10 million by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.The grant to the Four Corners Youth Consortium, agroup of academic medical centers studying pediatric concussions, will supportConcussion Assessment, Research and Education for Kids, or CARE4Kids, a multisite study that will enroll more than 1,300 children and teens nationwide, including an estimated 240 in Southern California.CARE4Kids re...
Source: UCLA Newsroom: Health Sciences - October 7, 2021 Category: Universities & Medical Training Source Type: news

Q & A: Dr. Thomas Rando on preventing age-related diseases and turning discoveries into cures
For Dr. Thomas Rando, the path to becoming a physician-scientist began with something that hedidn ’t learn in high school biology.After one class that touched on the connections between neurons and muscle fibers, Rando took it upon to himself to find all the information he could about how cells communicate through electrical signals.Soon, he began pursuing that interest at Harvard University, where he completed his undergraduate work, a doctorate in cell and developmental biology and his medical degree.Rando joined the neurology faculty at the Stanford University School of Medicine in 1995.There, he founded a clinic to t...
Source: UCLA Newsroom: Health Sciences - December 10, 2021 Category: Universities & Medical Training Source Type: news

Ditching cigarettes for smokeless tobacco can help cut cardiovascular risks, study finds
Regular smokers are at heightened risk of developing cardiovascular disease, but crushing the butts in favor of a “smokeless” alternative like chewing tobacco, snuff or tobacco lozenges may go a long way toward bringing the danger down to a more normal level, a new UCLA-led study shows.The findings also indicate that the primary culprit in smokers ’ increased risk is not nicotine but other chemicals found in tobacco smoke. Both cigarettes and smokeless tobacco products contain large quantities of nicotine.The study,published today in the journal Nicotine and Tobacco Research, involved a team of researchers from UCLA...
Source: UCLA Newsroom: Health Sciences - January 6, 2022 Category: Universities & Medical Training Source Type: news

Scientists develop blueprint for turning stem cells into sensory interneurons
Key takeaways:Just like the real thing.The stem cell –derived interneurons, which play a role in sensations like touch and pain, are indistinguishable from their real-life counterparts in the body.Tomorrow ’s therapies. In addition to potential treatments for injury-related sensation loss, the discovery could lead to new methods for screening drugs for chronic pain.Moving forward. While stem cells from mice were used in the research, scientists are now working to replicate the findings with human cells.Researchers at the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have develop...
Source: UCLA Newsroom: Health Sciences - July 19, 2022 Category: Universities & Medical Training Source Type: news

Professor elected to National Academy of Medicine
Dr. Arleen Brown, professor of medicine in the division of general internal medicine and health services research at the David Geffen School of Medicine at UCLA, has been elected to the National Academy of Medicine.Brown, who is also co-director of the UCLA Clinical and Translational Science Institute and chief of the division of general internal medicine and health services research at Olive View-UCLA Medical Center, was one of 100 new members announced today during the academy ’s annual meeting in Washington, D.C.She was recognized as “a pioneer in understanding how community, policy, health system, and individual fa...
Source: UCLA Newsroom: Health Sciences - October 18, 2022 Category: Universities & Medical Training Source Type: news