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Source: UCLA Newsroom: Health Sciences

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Total 132 results found since Jan 2013.

Scientists jump-start two people ’s brains after coma
In 2016, a team led by UCLA ’s Martin Monti reported that a 25-year-old man recovering from a coma had made remarkable progress following a treatment to jump-start his brain using ultrasound.Wired U.K. called the news one of the  best things that happened in 2016. At the time, Monti acknowledged that although he was encouraged by the outcome, it was possible the scientists had gotten a little lucky.Now, Monti and colleagues report that two more patients with severe brain injuries — both had been in what scientists call a long-term “minimally conscious state” — have made impressive progress thanks to the same te...
Source: UCLA Newsroom: Health Sciences - January 27, 2021 Category: Universities & Medical Training Source Type: news

Tomato concentrate could help reduce chronic intestinal inflammation associated with HIV
New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke.The findings provide clues to how the altered intestinal tract affects disease-causing inflammation in people with chronic HIV infection, suggesting that targeting the inflamed intestinal wall may be a novel way to prevent the systemic inflammation that persists even when antiviral therapy is effective in controlling a person ’s HIV.Th...
Source: UCLA Newsroom: Health Sciences - January 11, 2022 Category: Universities & Medical Training Source Type: news

Pesticides and Parkinson's: UCLA researchers uncover further proof of a link
For several years, neurologists at UCLA have been building a case that a link exists between pesticides and Parkinson's disease. To date, paraquat, maneb and ziram — common chemicals sprayed in California's Central Valley and elsewhere — have been tied to increases in the disease, not only among farmworkers but in individuals who simply lived or worked near fields and likely inhaled drifting particles.   Now, UCLA researchers have discovered a link between Parkinson's and another pesticide, benomyl, whose toxicological effects still linger some 10 years after the chemical was banned by the U.S. Environment...
Source: UCLA Newsroom: Health Sciences - January 3, 2013 Category: Universities & Medical Training Source Type: news

UCLA Nursing research on women and heart disease among key topics at nursing conference
New findings on the role gender plays in the diagnosis, treatment and prevention of heart disease will be among the research topics highlighted by faculty members and students from the UCLA School of Nursing at the annual Western Institute of Nursing Conference, which runs from April 11 to 13 in Anaheim, Calif.   At a special state-of-the-science panel on Saturday, April 13, UCLA professor Lynn V. Doering will present a review of gender differences in identification, treatment and outcomes for cardiovascular disease, with a focus on coronary atherosclerosis, heart failure and stroke. During the same panel, UCLA profes...
Source: UCLA Newsroom: Health Sciences - April 9, 2013 Category: Universities & Medical Training Source Type: news

Boosting 'cellular garbage disposal' can delay the aging process, UCLA biologists report
UCLA life scientists have identified a gene previously implicated in Parkinson's disease that can delay the onset of aging and extend the healthy life span of fruit flies. The research, they say, could have important implications for aging and disease in humans.   The gene, called parkin, serves at least two vital functions: It marks damaged proteins so that cells can discard them before they become toxic, and it is believed to play a key role in the removal of damaged mitochondria from cells.   "Aging is a major risk factor for the development and progression of many neurodegenerative diseases," said David Walke...
Source: UCLA Newsroom: Health Sciences - May 6, 2013 Category: Universities & Medical Training Source Type: news

WALL-E, meet EVA: 'Robo-doc' navigates on its own, frees doctors to focus on the critically ill
Ronald Reagan UCLA Medical Center, the world's first hospital to introduce a remote-presence robot into its neurological intensive-care unit in 2005, now welcomes the RP-VITA, the first robot able to navigate the hospital on its own.   UCLA staff affectionately dubbed the 5'5", 176-pound robot "EVA," for executive virtual attending physician. Unlike earlier models that physicians steered via a computer-linked joystick, this version drives on auto-pilot, freeing doctors to devote more time to patient care.   "During a stroke, the loss of a few minutes can mean the difference between preserving or losing brain func...
Source: UCLA Newsroom: Health Sciences - May 6, 2013 Category: Universities & Medical Training Source Type: news

Jekyll into Hyde: Breathing auto emissions turns HDL cholesterol from 'good' to 'bad'
Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein (HDL) cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries.    In addition to changing HDL from "good" to "bad," the inhalation of emissions activates other components of oxidation, the early cell and tissue damage that causes inflammation, leading to hardening of the arteries, according to the research team, which included scientists from UCLA and other institutions.   The findings of this early study, done in mice, are available in...
Source: UCLA Newsroom: Health Sciences - May 15, 2013 Category: Universities & Medical Training Source Type: news

Fat chance: Scientists unexpectedly discover stress-resistant stem cells in adipose tissue
Researchers from the UCLA Department of Obstetrics and Gynecology have isolated a new population of primitive, stress-resistant human pluripotent stem cells that are easily derived from fat tissue and are able to differentiate into virtually every cell type in the human body without genetic modification.   The cells, called multi-lineage stress-enduring stem cells from adipose tissue (Muse-AT), were discovered by "scientific accident" when a piece of equipment failed in the laboratory, killing all the stem cells in an experiment except the Muse-AT cells.   The UCLA team further discovered that not only are Muse-A...
Source: UCLA Newsroom: Health Sciences - June 5, 2013 Category: Universities & Medical Training Source Type: news

Growth, not just size, boosts brain aneurysms' risk of bursting
Brain aneurysms of all sizes — even small ones the size of a pea — are up to 12 times more likely to rupture if they are growing, according to a new UCLA study.   Published July 2 in the online edition of the journal Radiology, the discovery counters current guidelines suggesting that small aneurysms pose a low risk for rupture, and it emphasizes the need for regular monitoring and earlier treatment.   "Until now, we believed that large aneurysms presented the highest risk for rupture and that smaller aneurysms may not require monitoring," said lead author Dr. J. Pablo Villablanca, chief of diagn...
Source: UCLA Newsroom: Health Sciences - July 2, 2013 Category: Universities & Medical Training Source Type: news

California Health Interview Survey releases new 2011-12 data on health of Californians
The California Health Interview Survey (CHIS) today released new data based on interviews with more than 44,000 households in California. The survey, conducted by the UCLA Center for Health Policy Research, covered hundreds of topics affecting state residents' health and well-being. (See a complete list of topics here.)   Data on nearly 200 of these topics were released today on AskCHIS, the center's award-winning, free, easy-to-use Web tool that provides data by state, region, county and some service-planning areas in Los Angeles and San Diego counties. Even more data were released through free, downloadable pub...
Source: UCLA Newsroom: Health Sciences - August 8, 2013 Category: Universities & Medical Training Source Type: news

Lack of parental warmth, abuse in childhood linked to multiple health risks in adulthood
This study was also supported by the MacArthur Research Network on Socioeconomic Status and Health through grants from the John D. and Catherine T. MacArthur Foundation, and by grant T32-MH19925 and the Cousins Center for Psychoneuroimmunology at the UCLA.   The UCLA Cousins Center for Psychoneuroimmunology encompasses an interdisciplinary network of scientists working to advance the understanding of psychoneuroimmunology by linking basic and clinical research programs and by translating findings into clinical practice. The center is affiliated with the Semel Institute for Neuroscience and Human Behavior and the David...
Source: UCLA Newsroom: Health Sciences - October 1, 2013 Category: Universities & Medical Training Source Type: news

Tomato therapy: Engineered veggies target intestinal lipids, improve cholesterol
UCLA researchers report that tiny amounts of a specific type of lipid in the small intestine may play a greater role than previously thought in generating the high cholesterol levels and inflammation that lead to clogged arteries.   The team also found they could reduce the negative effects of these lipids in mice by feeding the animals a new genetically engineered tomato being developed at UCLA that is designed to mimic HDL ("good") cholesterol.   The study, published in the December issue of the Journal of Lipid Research with an accompanying editorial, focused on a group of lipids found in the sma...
Source: UCLA Newsroom: Health Sciences - November 13, 2013 Category: Universities & Medical Training Source Type: news

Researchers ID more pesticides linked to Parkinson's, gene that increases risk
This report provides evidence for the relevance of ALDH inhibition in Parkinson's disease pathogenesis, identifies pesticides that should be avoided to reduce the risk of developing Parkinson's disease and suggests that therapies modulating ALDH enzyme activity or otherwise eliminating toxic aldehydes should be developed and tested to potentially reduce Parkinson's disease occurrence or slow its progression, particularly for patients exposed to pesticides," the study states.   The study was funded in part by the National Institute of Environmental Health Sciences (P01ES016732, R01ES010544, 5R21ES16446-2 and U54ES0120...
Source: UCLA Newsroom: Health Sciences - February 3, 2014 Category: Universities & Medical Training Source Type: news

Tweaking potassium levels in brain could be a key to fighting Huntington's disease
By boosting the ability of a specific type of cell to absorb potassium in the brain, UCLA researchers were able to improve walking and prolong survival in a mouse model of Huntington's disease.   Their findings, published March 30 in the online edition of the journal Nature Neuroscience, could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans.   Huntington's disease is passed from parent to child through a mutation in the huntingtin gene. By killing brain cells called neurons, the disorder gradually deprives patients of their ability to walk, speak, sw...
Source: UCLA Newsroom: Health Sciences - March 31, 2014 Category: Universities & Medical Training Source Type: news

Potassium in brain could be key to fighting Huntington's disease
By boosting the ability of a specific type of cell to absorb potassium in the brain, UCLA researchers were able to improve walking and prolong survival in a mouse model of Huntington's disease.   Their findings, published March 30 in the online edition of the journal Nature Neuroscience, could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans.   Huntington's disease is passed from parent to child through a mutation in the huntingtin gene. By killing brain cells called neurons, the disorder gradually deprives patients of their ability to walk, speak, swallow, breat...
Source: UCLA Newsroom: Health Sciences - March 31, 2014 Category: Universities & Medical Training Source Type: news