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Influence of age on links between major modifiable risk factors and stroke occurrence in West Africa
BackgroundThe burden of stroke in Africa is high. Understanding how age associates with major modifiable stroke risk factors could inform tailored demographic stroke prevention strategies.PurposeTo quantify the magnitude and direction of the effect sizes of key modifiable stroke risk factors according to three age groups: 65 years (elderly) in West Africa.MethodsThis was a case-control study involving 15 sites in Ghana and Nigeria. Cases included adults aged ≥18 years with CT/MRI scan-typed stroke.
Source: Journal of the Neurological Sciences - July 8, 2021 Category: Neurology Authors: Fred S. Sarfo, Onoja Akpa, Bruce Ovbiagele, Albert Akpalu, Kolawole Wahab, Morenikeji Komolafe, Reginald Obiako, Lukman Owolabi, Godwin O. Osaigbovo, Carolyn Jenkins, Godwin Ogbole, Adekunle Fakunle, Hemant K. Tiwari, Oyedunni Arulogun, Donna K. Arnett, O Source Type: research

Letter to editor: Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?
We read the article “Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?” [1] with great interest. The authors have presented a concise and informative summary of the use of MRI in ischemic stroke care, emphasizing its significance in diagnosis, management, and secondary pr evention. We appreciate the authors for presenting a comprehensive summary of the use of MRI in ischemic stroke care. However, we have certain points to make about the comparison of the MR scanners provided in this article.
Source: Journal of the Neurological Sciences - March 31, 2023 Category: Neurology Authors: Alex Panther Source Type: research

Post-stroke depression in Ghana: Characteristics and correlates
Poststroke depression (PSD) is prevalent and is an important determinant of functional recovery, quality of life and mortality after stroke. Scanty data on the nature of PSD among stroke survivors in sub-Saharan Africa prompted this study.
Source: Journal of the Neurological Sciences - June 20, 2017 Category: Neurology Authors: Fred Stephen Sarfo, Carolyn Jenkins, Arti Singh, Mayowa Owolabi, Akin Ojagbemi, Nathaniel Adusei, Raelle Saulson, Bruce Ovbiagele Source Type: research

Hyperdense middle cerebral artery sign and response to combination of mechanical Thrombectomy plus intravenous thrombolysis in acute stroke patients
Combining intra-arterial mechanical thrombectomy (IAMT) and intravenous thrombolysis (IVT) has shown to have an excellent recanalization rate and better clinical outcome in acute ischemic stroke (AIS) patients. Hyperdense middle cerebral artery sign (HMCAS) on pretreatment non-contrast head CT scan of AIS patients is one of the early ischemic radiological findings in middle cerebral artery territory AIS. We aimed to evaluate whether the presence of HMCAS predicts the outcome of AIS patients receiving combination therapy with IAMT and IVT.
Source: Journal of the Neurological Sciences - August 16, 2021 Category: Neurology Authors: Ashkan Mowla, Seyed-Mostafa Razavi, Navdeep S. Lail, Pegah Mohammadi, Peyman Shirani, Katelyn S. Kavak, Robert N. Sawyer, Haris Kamal Source Type: research

MRI scout images can detect the acute intracerebral hemorrhage on CT
We examined whether MRI scout imaging can detect ICHs observed by computed tomography (CT).
Source: Journal of the Neurological Sciences - February 3, 2018 Category: Neurology Authors: Toshiyuki Hayashi, Junya Aoki, Kentaro Suzuki, Yuki Sakamoto, Satoshi Suda, Seiji Okubo, Masahiro Mishina, Kazumi Kimura Source Type: research

Warfarin-associated intracerebral hemorrhage: Volume, anticoagulation intensity and location
Conclusions: Patients with warfarin-associated ICH have a predilection for brainstem ICH. After adjustment for ICH location, no relationship between admission INR and hematoma volume was found.
Source: Journal of the Neurological Sciences - August 1, 2013 Category: Neurology Authors: Minmin Ma, Atte Meretoja, Leonid Churilov, Gagan J. Sharma, Søren Christensen, Xinfeng Liu, Louise Weir, Stephen M. Davis, Bernard Yan Tags: Original Articles Source Type: research

Cerebral microbleeds in a multiethnic elderly community: Demographic and clinical correlates
Conclusions: Microbleeds in deep and lobar locations are associated with worse outcomes than microbleeds in either location alone, although the presence of lobar microbleeds appears to be more clinically relevant.Highlights:
Source: Journal of the Neurological Sciences - July 21, 2014 Category: Neurology Authors: Anne F. Wiegman, Irene B. Meier, Nicole Schupf, Jennifer J. Manly, Vanessa A. Guzman, Atul Narkhede, Yaakov Stern, Sergi Martinez-Ramirez, Anand Viswanathan, José A. Luchsinger, Steven M. Greenberg, Richard Mayeux, Adam M. Brickman Tags: Original Articles Source Type: research

Carotid Inflammation on F-fluorodeoxyglucose Positron Emission Tomography Associates With Recurrent Ischemic Lesions
Inflammation plays an important role in the development of ischemic stroke. We hypothesized that inflammation of carotid atherosclerosis, as measured by 18F-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET), associates with the early recurrent ischemic lesions (ERILs).
Source: Journal of the Neurological Sciences - October 11, 2014 Category: Neurology Authors: Hye-Jin Kim, Minyoung Oh, Dae Hyuk Moon, Kyung-Ho Yu, Sun U. Kwon, Jong S. Kim, Dong-Wha Kang Source Type: research

Hypertrophic olivary degeneration: Case series and review of literature
Hypertrophic Olivary Degeneration (HOD) is a rare neurological condition caused by trans-synaptic degeneration in the brainstem and cerebellum, resulting in varied clinical symptoms, classical being palatal tremors, along with characteristic imaging presentation. Large number of pathologic lesions can cause this condition, ranging from ischemic stroke to neoplasm. The most common conditions include hemorrhage, vascular malformations and infarct. Magnetic resonance scan (MRI) is the imaging modality of choice which shows signal changes with hypertrophy of the inferior olivary nucleus, as well as the primary underlying pathology.
Source: Journal of the Neurological Sciences - September 26, 2016 Category: Neurology Authors: Shyam Sabat, Neil Mannering, Amit Agarwal Tags: Review Article Source Type: research