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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 349 results found since Jan 2013.
Diffusion-weighted Imaging at b1000 for Identifying Intracerebral Hemorrhage: Preliminary Sensitivity, Specificity, and Inter-rater Variability
Conclusions: DW-MRI at b1000 has a diagnostic yield similar to NCCT for detecting ICH and superior to NCCT for detecting IS. Therefore, DW-MRI may be considered as the initial screening tool for imaging patients presenting with focal neurologic symptoms suggestive of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - May 5, 2014 Category: Neurology Authors: Galina Keigler, Ilan Goldberg, Roni Eichel, John M. Gomori, Jose E. Cohen, Ronen R. Leker Tags: Original Articles Source Type: research
The Great Imitator—Still Today! A Case of Meningovascular Syphilis Affecting the Posterior Circulation
We describe clinical features and imaging studies of a 50-year-old patient with Parinaud syndrome and a syphilitic dorsal midbrain infarction. Brain magnetic resonance imaging indicated vasculitis of the posterior circulation. The diagnosis of meningovascular syphilis was established by serum and cerebrospinal fluid examinations. Although rare, because of the high impact on treatment, clinicians should always be aware of meningovascular syphilis in the differential diagnosis of stroke, particularly in young and male patients with cryptogenic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 2, 2014 Category: Neurology Authors: Jochen Bäuerle, Anna Zitzmann, Karl Egger, Stephan Meckel, Cornelius Weiller, Andreas Harloff Tags: Case Report Source Type: research
Routine 24-Hour Computed Tomography Brain Scan is not useful in stable patients Post Intravenous Tissue Plasminogen Activator
Obtaining a routine computed tomography (CT) brain scan 24 hours after treatment with intravenous tissue plasminogen activator (IV-tPA) is included in the American Heart Association/American Stroke Association acute stroke guidelines. The usefulness of the test in stable patients is not known. We hypothesized that the results of routine, 24-hour post-treatment neuroimaging (CT or magnetic resonance imaging [MRI] brain scans) would not alter the management of clinically stable patients.
Source: Journal of Stroke and Cerebrovascular Diseases - December 8, 2015 Category: Neurology Authors: Mary Guhwe, Queen Utley-Smith, Robert Blessing, Larry B. Goldstein Source Type: research
Small Cortical Infarcts Transformed to Lobar Cerebral Microbleeds: A Case Series
Cerebral microbleeds (MBs) have been often observed due to the development of imaging devices, and are classified to deep and lobar MBs. Lobar MBs are strongly associated with cerebral amyloid angiopathy. Here, we report 3 cases of lobar MBs that developed after small cortical ischemic stroke. One case underwent carotid artery stenting for severe carotid stenosis, one was diagnosed with artery-to-artery embolism, and the other was embolic stroke of undetermined source. New small cortical infarctions were detected with diffusion-weighted magnetic resonance imaging (MRI).
Source: Journal of Stroke and Cerebrovascular Diseases - January 14, 2019 Category: Neurology Authors: Ai Ogawa Ito, Akihiro Shindo, Yuichiro Ii, Hidehiro Ishikawa, Akira Taniguchi, Masato Shiba, Naoki Toma, Hidenori Suzuki, Hidekazu Tomimoto Tags: Case Report Source Type: research
Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Associated With a Novel In-Frame Mutation in the NOTCH3 Gene in a Japanese Patient
Here, we report a case involving a 67-year-old Japanese woman with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) associated with a novel in-frame complex rearrangement in the NOTCH3 gene. The patient had gradually developed cognitive impairment since the occurrence of an ischemic stroke at the age of 53 years. Her mother had a history of stroke and dementia. Fluid-attenuated inversion recovery magnetic resonance imaging of the brain showed hyperintense lesions in the bilateral temporal poles, external capsules, and periventricular white matter accompanied by multiple c...
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2019 Category: Neurology Authors: Yuho Takeshi, Satoshi Suda, Takashi Shimoyama, Junya Aoki, Kentaro Suzuki, Seiji Okubo, Ikuko Mizuta, Toshiki Mizuno, Kazumi Kimura Tags: Case Report Source Type: research
The Medial Pontine Mid-Tegmentum Syndrome
Isolated pontine infarcts are common and are often associated with well-described syndromes that are classified based on their specific clinical presentation and arterial stroke territories. Here we present a case of acute combined diplopia and unilateral lower extremity sensory abnormality. Diffusion-weighted magnetic resonance imaging revealed a punctate area of acute ischemia in the right medial pontine mid-tegmentum. These findings suggest a unique pontine stroke syndrome characterized by acute ischemic injury at the intersection of the medial lemniscus and cranial nerve VI.
Source: Journal of Stroke and Cerebrovascular Diseases - March 23, 2020 Category: Neurology Authors: Lara C. Wadi, Michael J. Kim, Mark J. Fisher Tags: Case Report Source Type: research
Iodinated Contrast Extravasation on Post-Revascularization Computed Tomography Mimics Magnetic Resonance Hyperintense Acute Reperfusion Marker: A Case Study
Hyperintense reperfusion marker (HARM) on post-contrast magnetic resonance imaging (MRI) fluid attenuated inversion recovery (FLAIR) represents gadolinium contrast extravasation in the setting of acute ischemic stroke and is a common finding after revascularization therapies. Clinically, it is a marker of blood brain barrier (BBB) disruption, predictor of hemorrhagic transformation, and predictor of poor clinical outcome in ischemic stroke. Here, we describe a case where a patient underwent mechanical thrombectomy and was later found to have evidence of contrast extravasation on CT imaging, in th e same locations found...
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2020 Category: Neurology Authors: Justin De Prey, Crystal Yu, Franklin D. Echevarria, Izabella Barreto, John H. Rees, Reordan O. DeJesus, Alexis N. Simpkins Tags: Case Report Source Type: research
Prevalence and Risk Factors of Silent Cerebral Microbleeds in Patients with Coronary Artery Disease
Coronary artery disease (CAD) and stroke are the two most common causes of death and disability worldwide, notably affecting aging populations.1 These cardiovascular disorders lead to impaired activity daily life and increase the risk of dementia.2,3 Brain magnetic resonance imaging (MRI) has excellent sensitivity in detecting ischemic lesions and can reveal asymptomatic, small, cerebral hemorrhages that are called cerebral microbleeds (CMBs).4 A systematic review reported that microbleeds were present on the MRIs of 5% of healthy adults, 34% of patients with ischemic stroke, and 60% of patients with nontraumatic intracerebral hemorrhage.
Source: Journal of Stroke and Cerebrovascular Diseases - November 22, 2021 Category: Neurology Authors: Ryo Yokoyama, Yumiko Kanzaki, Tomohiko Watanabe, Kenichiro Yamamura, Tsuyoshi Komori, Yoshihiro Takeda, Osamu Nakajima, Koichi Sohmiya, Masaaki Hoshiga Source Type: research
Area postrema syndrome caused by medullary infarction
In the present study, we report a case of persistent intractable nausea and vomiting after a medullary infarction. Area postrema syndrome due to ischemic stroke is very rare. In this case, brain magnetic resonance imaging revealed an ischemic lesion in the lateral medulla extending caudally and dorsomedially. The patient presented with sustained nausea, vomiting, and poor oral intake over one month after the index stroke, even after resolution of dizziness and disappearance of nystagmus. She did not respond to intravenous metoclopramide with ondansetron.
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2022 Category: Neurology Authors: Seunghee Na, Dar Eun Jung, Eunbyol Hwang, Taewon Kim Tags: Case Report Source Type: research
Lower 25-hydroxyvitamin D is associated with severer white matter hyperintensity and cognitive function in patients with non-disabling ischemic cerebrovascular events
Vascular cognitive impairment (VCI) is the second most common type of cognitive impairment, referring to the entire spectrum of cognitive impairment contributed by cerebrovascular pathology1. Due to the progressively higher incidence of stroke and cerebrovascular diseases, VCI, including post-stroke cognitive impairment are the leading causes of disability epidemic worldwide2-3. White matter lesions, manifested as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI) scans, are one of the most common pathological characteristics of VCI4.
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2023 Category: Neurology Authors: Zhengsheng Gu, Xu Sun, Chenghao Wu, Binghan Li, Jingjing Chen, Weisen Wang, Xin Gao, Yuhao Tan, Bin Li, Ge Yin, Yawen Xu, Chenrui Song, Bingying Du, Xiaoying Bi Source Type: research
Apolipoprotein Epsilon 4 Allele Modifies Waist-to-Hip Ratio Effects on Cognition and Brain Structure
Conclusions: These findings suggest that associations between central adiposity and both neuropsychological performance and underlying brain structure are highly complex and must be considered in the context of possible modifying genetic influences.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2011 Category: Neurology Authors: David Zade, Alexa Beiser, Regina McGlinchey, Rhoda Au, Sudha Seshadri, Carole Palumbo, Philip A. Wolf, Charles DeCarli, William Milberg Tags: Original Articles Source Type: research
Examination Timing and Lesion Patterns in Diffusion-weighted Magnetic Resonance Imaging of Patients with Classically Defined Transient Ischemic Attack
Conclusions: Acute ischemic lesions on DWI were associated with time-to-DWI and LAA in patients with classically defined TIA. Additionally, we identified some differences in relating factors between patients with single and multiple DWI lesions. These results indicate that time-to-DWI and DWI lesion pattern may be important for the diagnosis and management of TIA.
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2013 Category: Neurology Authors: Tetsuya Miyagi, Toshiyuki Uehara, Kazumi Kimura, Yasushi Okada, Yasuhiro Hasegawa, Norio Tanahashi, Akifumi Suzuki, Shigeharu Takagi, Jyoji Nakagawara, Kazumasa Arii, Shinji Nagahiro, Kuniaki Ogasawara, Takehiko Nagao, Shinichiro Uchiyama, Masayasu Matsum Tags: Original Articles Source Type: research
Delayed Recurrent Stroke in a Young Patient with Acute Posterior Multifocal Placoid Pigment Epitheliopathy
We report a 15-year-old patient who had bilateral APMPPE, which was successfully treated with corticosteroids. One year later he presented with transient dysarthria and right hemiparesis. Brain magnetic resonance imaging (MRI) showed bilateral ischemic lesions in both lenticular nuclei and corona radiata. Brain MRI performed 3 months later revealed a new asymptomatic ischemic lesion. Cerebral angiography showed diffuse multifocal segmental vessel narrowing. The cerebrospinal fluid showed mononuclear pleocytosis in keeping with vasculitis. We started corticosteroid treatment, which lasted 10 months. Currently, after 2 years...
Source: Journal of Stroke and Cerebrovascular Diseases - November 26, 2012 Category: Neurology Authors: José Manuel Matamala, Walter Feuerhake, Renato Verdugo Tags: Case Reports Source Type: research
High-resolution Magnetic Resonance Imaging Reveals Hidden Etiologies of Symptomatic Vertebral Arterial Lesions
Conclusions: The application of HR-MRI in stroke patients with VA pathologies enabled the authors to determine the underlying pathophysiologies. These findings could be used to improve risk stratification and treatment decision making in symptomatic intracranial VA disease.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Jong-Won Chung, Beom Joon Kim, Byung Se Choi, Chul Ho Sohn, Hee-Joon Bae, Byung-Woo Yoon, Seung-Hoon Lee Tags: Original Articles Source Type: research
Gravity-dependent Nystagmus and Inner-Ear Dysfunction Suggest Anterior and Posterior Inferior Cerebellar Artery Infarct
Cerebellar lesions may present with gravity-dependent nystagmus, where the direction and velocity of the drifts change with alterations in head position. Two patients had acute onset of hearing loss, vertigo, oscillopsia, nausea, and vomiting. Examination revealed gravity-dependent nystagmus, unilateral hypoactive vestibulo-ocular reflex (VOR), and hearing loss ipsilateral to the VOR hypofunction. Traditionally, the hypoactive VOR and hearing loss suggest inner-ear dysfunction. Vertigo, nausea, vomiting, and nystagmus may suggest peripheral or central vestibulopathy. The gravity-dependent modulation of nystagmus, however, ...
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Aasef G. Shaikh, Benjamin R. Miller, Sophia Sundararajan, Bashar Katirji Tags: Case Reports Source Type: research
