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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 349 results found since Jan 2013.
Ulcerated Carotid Plaques with Ultrasonic Echolucency Are Causatively Associated with Thromboembolic Cerebrovascular Events
The presence of ulcerated carotid plaques is a risk factor for ischemic stroke, which is associated with thromboembolism. We evaluated the relationship between ulcerated carotid plaques and cerebrovascular events in patients with acute ischemic stroke or transient ischemic attack. We extracted 48 consecutive patients with ulcerated carotid plaques from a cohort of 1111 patients with acute ischemic stroke or transient ischemic attack. All patients were evaluated by carotid ultrasonography and diffusion-weighted magnetic resonance imaging. We defined thromboembolic events by excluding potential cardiac sources of embolism, s...
Source: Journal of Stroke and Cerebrovascular Diseases - August 8, 2011 Category: Neurology Authors: Tomomi Nakamura, Yukiko Tsutsumi, Yuko Shimizu, Shinichiro Uchiyama Tags: Original Articles Source Type: research
Magnetic Resonance Angiography–Diffusion Mismatch Reflects Diffusion–Perfusion Mismatch in Patients with Hyperacute Cerebral Infarction
Conclusions: In hyperacute cerebral infarction within 3 hours after onset, MDM, as compared with CDM, was able to detect DPM with higher sensitivity and specificity. This suggests that MDM is more reflective of DPM.
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2011 Category: Neurology Authors: Ichiro Deguchi, Tomohisa Dembo, Takuya Fukuoka, Harmitsu Nagoya, Hajime Maruyama, Yuji Kato, Yasuko Ohe, Yohsuke Horiuchi, Akira Uchino, Norio Tanahashi Tags: Original Articles Source Type: research
Early Clinical Signs, Lesion Localization, and Prognostic Factors in Unilateral Symptomatic Internal Carotid Artery Occlusion
Conclusions: In unilateral symptomatic intracranial carotid artery occlusion, poor prognosis and high mortality–associated territorial stroke pattern is frequently observed. Besides, presence of severe stenosis or occlusion and absence of collateral circulation in MCA are associated with poor prognosis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 18, 2014 Category: Neurology Authors: Sibel Güler, Ufuk Utku, Özer Aynaci Tags: Original Articles Source Type: research
Comparison of Fast MRI-based Individual Thrombolysis Therapy for Patients with Superacute Infarction
Conclusions: Our study suggested that fast MR-based thrombolysis using rt-PA was safe and reliable in superacute infarction within 4.5 hours and 4.5-12 hours poststroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2014 Category: Neurology Authors: Qingke Bai, Zhenguo Zhao, Haijing Sui, Xiuhai Xie, Juan Chen, Juan Yang, Yuan Zhou Tags: Original Articles Source Type: research
“Invisible” Brain Stem Infarction at the First Day
Background: In specific stroke cases, serial diffusion-weighted magnetic resonance imaging (DW MRI) on day 1 was unable to show a lesion, whereas that on day 4 and later clearly revealed a lesion. However, clinical features of this phenomenon (“invisible” brain stem infarction [IBI] at the first day) have not been fully delineated.Methods: We retrospectively recruited 212 stroke patients in the Emergency Unit and Neurology Department. Among these, we studied patients with IBI. Definition of IBI is that acute and clear brain stem symptoms/signs on arrival were ameliorated at discharge and appearance of high signal inten...
Source: Journal of Stroke and Cerebrovascular Diseases - May 8, 2014 Category: Neurology Authors: Yohei Tsuyusaki, Ryuji Sakakibara, Masahiko Kishi, Fuyuki Tateno, Yosuke Aiba, Tsuyoshi Ogata, Takeki Nagao, Hitoshi Terada, Tsutomu Inaoka Tags: Original Articles Source Type: research
Detection of Vessel Wall Lesions in Spontaneous Symptomatic Vertebrobasilar Artery Dissection Using T1-weighted 3-dimensional Imaging
Conclusions: The T1W 3D-VWI can directly visualize vessel wall iVBD lesions during the acute period of stroke compared with multisequence MRI.
Source: Journal of Stroke and Cerebrovascular Diseases - August 29, 2014 Category: Neurology Authors: Tatsunori Natori, Makoto Sasaki, Mitsuharu Miyoshi, Hideki Ohba, Mao Yamaguchi Oura, Shinsuke Narumi, Taisuke Harada, Hiroyuki Kabasawa, Yasuo Terayama Tags: Original Articles Source Type: research
Recurrent Large Volume Silent Strokes in Sickle Cell Disease
We report a 30-year-old woman who presented a large volume silent stroke followed 2 months later by a second large volume stroke that manifested only with transient arm weakness. In the acute phase, magnetic resonance angiography revealed a segmental stenosis of the 2 different large intracranial vessels supplying the stroke territories. Partial regression of vascular stenosis was revealed by a follow-up magnetic resonance imaging.
Source: Journal of Stroke and Cerebrovascular Diseases - September 17, 2014 Category: Neurology Authors: Massimo Marano, Carlo Quattrocchi, Ombretta Annibali, Giuseppe Avvisati, Vincenzo Di Lazzaro Tags: Case Report Source Type: research
Brain Abnormalities in Pontine Infarction: A Longitudinal Diffusion Tensor Imaging and Functional Magnetic Resonance Imaging study
Stroke refers to poor blood flow to the brain that leads to cell death and is one of the major threats to human life and health.1 Eighty percent of stroke are ischemic stroke.2 Among them, approximately 3% of ischemic strokes are solitary pontine infarctions.3 Pontine infarction is acute, the clinical manifestations are complicated, and the clinical manifestations vary greatly among individuals. Most surviving patients may have different degrees of motor dysfunction. How to make a reasonable and accurate assessment of the prognosis of patients with pontine infarction and carry out a series of rehabilitation treatments base...
Source: Journal of Stroke and Cerebrovascular Diseases - December 5, 2021 Category: Neurology Authors: Jing Li, Dong-Dong Rong, Yi Shan, Miao Zhang, Cheng Zhao, Jie Lu Source Type: research
Recurrent Intracerebral Hemorrhage in Patients With Hypertension is Associated With APOE Gene Polymorphism: A Preliminary Study
This study evaluates the roles of apolipoprotein E (APOE) and α-1 antichymotrypsin (ACT) genes in patients with recurrent hypertensive ICH and compares patients with nonrecurring hypertensive ICH and normal controls.Methods: Thirty-three recurrent and 101 nonrecurrent patients with hypertension and ICH were included. The demographic, stroke risk factors, and computed tomographic or magnetic resonance imaging findings were recorded. Magnetic resonance angiography or digital subtraction angiography and vasculitic profile were done in recurrent group to exclude secondary causes of ICH. APOE and ACT gene polymorphisms were as...
Source: Journal of Stroke and Cerebrovascular Diseases - March 12, 2012 Category: Neurology Authors: Usha K. Misra, Jayantee Kalita, Bindu I. Somarajan Tags: Original Articles Source Type: research
Clinical Features and Racial/Ethnic Differences Among the 3020 Participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) Trial
This study examined the baseline characteristics, racial/ethnic differences, and geographic differences among participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) study. The SPS3 trial enrolled patients who experienced a symptomatic small subcortical stroke (lacunar stroke) within the previous 6 months and an eligible lesion on detected on magnetic resonance imaging. The patients were randomized, in a factorial design, to antiplatelet therapy (aspirin 325 mg daily plus clopidogrel 75 mg daily vs aspirin 325 mg daily plus placebo) and to one of two levels of systolic blood pressure targets (“intensive” [
Source: Journal of Stroke and Cerebrovascular Diseases - April 19, 2012 Category: Neurology Authors: Carole L. White, Jeff M. Szychowski, Ana Roldan, Marie-France Benavente, Edwin J. Pretell, Oscar H. Del Brutto, Carlos S. Kase, Antonio Arauz, Brett C. Meyer, Irene Meissner, Bart M. Demaerschalk, Leslie A. McClure, Christopher S. Coffey, Lesly A. Pearce, Tags: Original Articles Source Type: research
A Mismatch Between the Abnormalities in Diffusion- and Susceptibility-Weighted Magnetic Resonance Imaging May Represent an Acute Ischemic Penumbra with Misery Perfusion
In this study we make the first case report of blunt cervical trauma leading to a stroke, demonstrating the disparity between diffusion-weighted imaging (DWI) and SWI changes, or DWI-SWI mismatch, in the acute ischemic brain. The area of mismatch between a smaller DWI cytotoxic edema and a larger SWI misery perfusion in our patient matured into a complete infarction with time. The DWI-SWI mismatch may signify the presence of an ischemic penumbra, and provide information about viability of the brain tissue at risk of potential infarction if without early reperfusion.
Source: Journal of Stroke and Cerebrovascular Diseases - February 14, 2013 Category: Neurology Authors: Masayuki Fujioka, Kazuo Okuchi, Asami Iwamura, Toshiaki Taoka, Bo K. Siesjö Tags: Case Reports Source Type: research
Amusia for Pitch Caused by Right Middle Cerebral Artery Infarct
A 61-year-old right-handed man with hypertension and dyslipidemia noted that he was singing along to classic rock songs on his car radio, but his voice was off pitch. Six days later, a magnetic resonance imaging scan of his brain revealed a cerebral infarct of the right temporal parietal cortex and insula. Case reports of the precise anatomic correlates of disordered pitch musical processing have been few and fragmentary. The anatomic involvement of our case coincides with the areas of involvement in 3 previously reported cases. Increased awareness of amusia as a rare clinical presentation of stroke should lead to earlier stroke intervention.
Source: Journal of Stroke and Cerebrovascular Diseases - August 9, 2012 Category: Neurology Authors: M. Seth Hochman, Kevin J. Abrams Tags: Case Reports Source Type: research
Cerebral Infarction in a Case of Parry-Romberg Syndrome
Our objective is to report a rare coexistence of Parry-Romberg disease and ischemic stroke. Here, we report the case of a 34-year-old woman with Parry-Romberg syndrome who developed cerebral infarction. This patient developed sudden left-sided weakness and was admitted to our hospital. Magnetic resonance imaging revealed acute cerebral infarction in the posterior limb of the right internal capsule. The patient had been diagnosed with Parry-Romberg syndrome at the age of 12, and she had a history of migraine without aura. Transesophageal echocardiography revealed a patent foramen ovale, but no atrial septal aneurysm or deep...
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2013 Category: Neurology Authors: Yuji Tomizawa, Ryota Tanaka, Kiyoshi Sekiguchi, Yutaka Oji, Yasutaka Tanaka, Kazuo Yamashiro, Nobutaka Hattori Tags: Case Reports Source Type: research
Profile of Patients with Cerebral Venous Sinus Thrombosis with Cerebellar Involvement
Conclusions: Cerebellar involvement in CVT is very rare, and high index of suspicion is required for diagnosis. Imaging with CT and MRI will help in confirming the diagnosis. Conventional anticoagulation is effective in treatment. Mortality was 33%, and there was no disability in survivors.
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2013 Category: Neurology Authors: Girish B. Kulkarni, Veerendrakumar Mustare, Mirza M. Abbas Tags: Original Articles Source Type: research
Safety of Intravenous Tissue Plasminogen Activator Administration with Computed Tomography Evidence of Prior Infarction
Background: Prior stroke within 3 months excludes patients from thrombolysis; however, patients may have computed tomography (CT) evidence of prior infarct, often of unknown time of origin. We aimed to determine if the presence of a previous infarct on pretreatment CT is a predictor of hemorrhagic complications and functional outcomes after the administration of intravenous (IV) tissue plasminogen activator (tPA).Methods: We retrospectively analyzed consecutive patients treated with IV tPA at our institution from 2009-2011. Pretreatment CTs were reviewed for evidence of any prior infarct. Further review determined if any ...
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2014 Category: Neurology Authors: Michael J. Lyerly, J. Thomas Houston, Amelia K. Boehme, Karen C. Albright, Reza Bavarsad Shahripour, Paola Palazzo, Muhammed Alvi, Pawan V. Rawal, Niren Kapoor, April Sisson, Anne W. Alexandrov, Andrei V. Alexandrov Tags: Original Articles Source Type: research
