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Computed Tomography Angiogram Derived From Computed Tomography Perfusion Done With Low Iodine Volume Protocol Preserves Diagnostic Yield for Middle Cerebral Artery-M2 Occlusions
In this study, we test reliability for identifying M2 occlusions on CTA derived from CTP. Methods: Through a retrospective search of the institutional thrombectomy database, we identified 28 cases with M2-MCA occlusion, of which 24 met the inclusion criteria for analysis.
Source: Journal of Stroke and Cerebrovascular Diseases - October 25, 2019 Category: Neurology Authors: Kaustubh Limaye, Adam Bryant, Girish Bathla, Biyue Dai, Sami Al Kasab, Amir Shaban, Edgar A. Samaniego, David Hasan, Bruno Policeni, Enrique Leira, Colin Derdeyn, Santiago Ortega-Gutierrez Source Type: research

Computed Tomography Perfusion Showing Cerebral Hypoperfusion in a Patient with Acute Cerebral Venous Sinus Thrombosis —A Case Report
We report the case of a patient with acute CVST, showing perfusion abnormalities on computed tomography perfusion with perfusion defect in the relevant hemisphere. The defect was found in a region adjacent to the occluded sinus and was not corresponding to an arterial territory. To the best of our knowledge this is the first ever report on CT perfusion abnormalities few hours after acute symptom onset in CVST.
Source: Journal of Stroke and Cerebrovascular Diseases - February 17, 2020 Category: Neurology Authors: Robbert-Jan van Hooff, Jesper Gyllenborg, Kayal Jesuratnam-Nielsen, Troels Wienecke Tags: Case Report Source Type: research

Ischemic Tolerance Evaluated by Computed Tomography Perfusion during Balloon Test Occlusion
In this study, we evaluated the utility of computed tomography (CT) perfusion during BTO to quantify ischemic tolerance for detecting delayed ischemic stroke. Materials and Methods: Forty-one patients who underwent BTO for the internal carotid artery were included.
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2020 Category: Neurology Authors: Tomoyoshi Kuribara, Takeshi Mikami, Satoshi Iihoshi, Kei Miyata, Sangnyon Kim, Yuka Kawata, Katsuya Komatsu, Yusuke Kimura, Rei Enatsu, Yukinori Akiyama, Toru Hirano, Nobuhiro Mikuni Source Type: research

Racial Disparities in Magnetic Resonance Imaging and Perfusion-Diffusion Mismatch
The central concept of mismatch between perfusion and diffusion targets identified by magnetic resonance imaging offers an approximation of the tissue at risk of infarction if reperfusion is not achieved. This measure is becoming increasingly relevant in determining eligibility for and prognosis following thrombolytic and endovascular treatments, particularly at extended time windows. A few studies have shown that Black stroke patients are more likely to suffer small-vessel ischemic strokes and fewer cardioembolic strokes occluding large vessels.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Benjamin Taylor King Tags: Poster 03 Source Type: research

Acute Thrombocytopenia After Tissue Plasminogen Activator for Stroke
An 88 year-old right-handed female with a history of atrial fibrillation presented with acute onset left-sided weakness, forced rightward gaze deviation, and neglect. She was found to have a right M1 occlusion and a favorable penumbra on CT Perfusion. She received 0.9 mg/kg (52.77 mg) of tPA with a 10% (5.27 mg) bolus given over the first minute. She was taken for thrombectomy with Thrombolysis in Cerebral Infarction (TICI) IIb revascularization. She received 1200 mL of heparin during thrombectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2020 Category: Neurology Authors: Jonathan Morena, Casey May, Tamara Strohm Tags: Case Report Source Type: research

Thalamic perforating artery stroke on computed tomography perfusion in a patient with coronavirus disease 2019
We present a case illustrating the value of CT perfusion to identify acute small subcortical infarcts in a patient with COVID-19 admitted to an intensive care unit for bilateral pneumonia and pulmonary embolism presenting with sudden right limb weakness.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2020 Category: Neurology Authors: Salvatore Rudilosso, Diana Esteller, Xabier Urra, Ángel Chamorro Tags: Case Report Source Type: research

Comparison of the Effectiveness of Ring-Stripping Retrograde Endarterectomy and Carotid Artery Crossover Bypass in the Treatment of Patients with Symptomatic Riles Type 1A Common Carotid Artery Occlusion
This study compares the effects of ring-stripping retrograde endarterectomy (RSRE) and carotid artery crossover bypass (CACB) on cerebral perfusion improvement in patients with symptomatic Riles type 1A CCAO. Methods: We conducted a retrospective analysis of symptomatic Riles type 1A CCAO patients treated at our centre. Postoperative improvements in the ipsilateral internal carotid artery (ICA) flow rate, ipsilateral cerebral blood perfusion (CBP) and the stroke recurrence rate were compared between patients who underwent RSRE and those who underwent CACB.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Chuan Chen, Cong Ling, Lun Luo, Haiyong He, Manting Li, Robin Bhattarai, Yuefei Guo, Hui Wang, Ying Guo Source Type: research

Preoperatively estimated graft flow rate contributes to the improvement of hemodynamics in revascularization for Moyamoya disease
Moyamoya disease is a cerebrovascular disease that is characterized by chronic progressive stenosis of the terminal portion of the internal carotid artery (ICA) on both sides of the brain, which results in an abnormal vascular network of the collateral pathways at the base of the brain.1,2 Therefore, patients with Moyamoya disease have a decreased cerebral blood flow (CBF) and reduced cerebral perfusion pressure,3 which can result in ischemic and/or hemorrhagic stroke. This hemodynamic condition can be evaluated using positron emission tomography (PET) or single-photon emission computed tomography (SPECT) as the gold standard procedure.
Source: Journal of Stroke and Cerebrovascular Diseases - November 7, 2020 Category: Neurology Authors: Tomoyoshi Kuribara, Takeshi Mikami, Katsuya Komatsu, Yusuke Kimura, Sangnyon Kim, Kei Miyata, Yukinori Akiyama, Rei Enatsu, Toru Hirano, Nobuhiro Mikuni Source Type: research

Early Neurological Deterioration and Hypoperfusion Volume Ratio on Arterial Spin Labeling in Patients with Acute Ischemic Stroke
This study aimed to explore the relation between HVR and early neurological deterioration (END) in AIS patients.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2021 Category: Neurology Authors: Min Zhang, Wusheng Zhu, Yi Ma, Kuankuan Huang, Shan Huang, Qian Chen, Wenwei Yun, Gelin Xu Source Type: research

Middle Cerebral Artery Pulsatility Index Correlates with Prognosis and Diastolic Dysfunctions in Acute Ischemic Stroke
Adequate tissue perfusion is a requirement for optimal organ function, and is dependent upon the distribution of cardiac output and local vasculature.1
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2022 Category: Neurology Authors: Takeo Sato, Akira Niijima, Ayumi Arai, Takahiro Maku, Haruhiko Motegi, Maki Takahashi, Hiroki Takatsu, Maki Tanabe, Teppei Komatsu, Kenichi Sakuta, Kenichiro Sakai, Yuka Terasawa, Tadashi Umehara, Shusaku Omoto, Hidetomo Murakami, Hidetaka Mitsumura, Yasu Source Type: research

Large Vessel Occlusion Sites Affect Agreement Between Outputs of Three Computed Tomography Perfusion Software Packages
Computed tomography perfusion (CTP) data are important for hyperacute stroke decision making. Available comparisons between outputs of different CTP software packages show variable outcomes. Evaluation for factors associated with agreement between the volume estimates is limited. We assessed for differences in core and penumbra volume estimates of three CTP software packages – AutoMIStar, RAPID, and Vitrea – and analyzed factors associated with agreement between the volume estimates.
Source: Journal of Stroke and Cerebrovascular Diseases - April 13, 2022 Category: Neurology Authors: Peter S.W. Park, Robbie Chan, Channa Senanayake, Stanley Tsui, Alun Pope, Helen M. Dewey, Philip M.C. Choi Source Type: research

Endovascular Thrombectomy Reduces Risk of Poor Functional Outcomes in Patients Presenting within 0-6 Hours with Large Ischemic Core Volumes on Computed Tomography Perfusion
Large vessel occlusion (LVO) stroke patients presenting with large ischemic core volumes (LICVs) on acute imaging have worse outcomes compared to those with smaller ischemic core volumes1 However, endovascular thrombectomy (EVT), compared with medical management (MM), may still be beneficial in this population according to a meta-analysis of patient-level data from early window randomized thrombectomy trials1 and a systematic review of patients presenting with LICVs on computed tomography (CT) or computed tomography perfusion (CTP)2
Source: Journal of Stroke and Cerebrovascular Diseases - May 11, 2022 Category: Neurology Authors: Rahul R. Karamchandani, Hongmei Yang, Tanushree Prasad, Dale Strong, Jeremy B. Rhoten, Gary Defilipp, Jonathan Clemente, William R. Stetler, Joe Bernard, Andrew W. Asimos Source Type: research

Cerebral perfusion imaging predicts final infarct volume after basilar artery thrombectomy
Cerebral perfusion imaging may be used to identify the ischemic core in acute ischemic stroke (AIS) patients with a large vessel occlusion of the anterior circulation; however, perfusion parameters that predict the ischemic core in AIS patients with a basilar artery occlusion (BAO) are poorly described. We determined which cerebral perfusion parameters best predict the ischemic core after successful endovascular thrombectomy (EVT) in BAO patients.
Source: Journal of Stroke and Cerebrovascular Diseases - November 23, 2022 Category: Neurology Authors: Nicole Yuen, Michael Mlynash, Andrea O'Riordan, Maarten Lansberg, Soren Christensen, Carlo W. Cereda, Giovanni Bianco, Dan-Victor Giurgiutiu, Fana Alemseged, Marco Pileggi, Bruce Campbell, Gregory W. Albers, Jeremy J. Heit Source Type: research

Comparing the benefit of ASPECTS on maximum intensity projection images of computed tomography angiography to source images and noncontract computed tomography in predicting infarct volume and collaterals extent
In acute ischemic strokes (AIS), the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) and CT perfusion (CTP) are commonly used to determine mechanical thrombectomy eligibility. Prior work suggests that CTA source image (CTA-SI) ASPECTS (CTAasp) and a newly described CTA maximum intensity projection (CTA-MIP) ASPECTS (MIPasp) better predict the final infarct core. Our goal was to compare MIPasp to CTAasp and non-contrast CT ASPECTS (NCCTasp) for predicting ischemic core and collaterals established by CTP.
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2023 Category: Neurology Authors: Seyed Amir Ebrahimzadeh, Elizabeth Du, Vladimir Ivanovic, Rafeeque A. Bhadelia, Lotfi Hacein-Bey, Magdy Selim, Yu-Ming Chang Source Type: research

Correlation Between Severity of Carotid Stenosis and Vascular Reserve Measured by Acetazolamide Brain Perfusion Single Photon Emission Computed Tomography
This study examined that relationship. A total of 56 ICAs in 43 patients were included. Computed tomography scan or magnetic resonance imaging showed no evidence of infarction in any of these patients. Both iodine-123-N-isopropyl-p-iodoamphetamine (123IMP)–single photon emission computed tomography (SPECT) in the resting state and 123IMP-SPECT with acetazolamide (ACZ) enhancement were performed. Quantitated cerebral blood flow (CBF) images were acquired with the 123IMP autoradiography technique. The mean CBF without ACZ administration (resting CBF) and CVR in the middle cerebral artery territory were calculated using ste...
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2011 Category: Neurology Authors: Noriaki Tomura, Takahiro Otani, Makoto Koga, Koichi Ishiyama Tags: Original Articles Source Type: research

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