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Source: Journal of Stroke and Cerebrovascular Diseases
Procedure: Perfusion
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Total 144 results found since Jan 2013.
Infarct Recurrence in Intracranial Atherosclerosis: Results from the MyRIAD Study
Intracranial atherosclerotic disease (ICAD) is a common cause of ischemic stroke with a high risk of clinical stroke recurrence. Multiple mechanisms may underlie cerebral ischemia in this condition. The study's objective is to discern the mechanisms of recurrent ischemia in ICAD through imaging biomarkers of impaired antegrade flow, poor distal perfusion, abnormal vasoreactivity, and artery-to-artery embolism.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2020 Category: Neurology Authors: Jose G. Romano, Shyam Prabhakaran, Azhar Nizam, Edward Feldmann, Rajbeer Sangha, George Cotsonis, Iszet Campo-Bustillo, Sebastian Koch, Tatjana Rundek, Marc I. Chimowitz, David S. Liebeskind, MyRIAD Investigators Source Type: research
Searching for Salvageable Brain: The Detection of Ischemic Penumbra Using Various Imaging Modalities?
Various imaging modalities are used to identify the ischemic penumbra in patients with acute ischemic stroke. Although single-photon emission computed tomography (CT), perfusion-weighted magnetic resonance imaging (MRI), and perfusion CT are used to evaluate residual cerebral blood flow in the ischemic area, validation of the perfusion threshold for the penumbra has not been established. The ischemic core corresponds generally to areas with early ischemic changes, such as parenchymal hypoattenuation on CT, restricted apparent diffusion coefficient on diffusion-weighted MRI, or very low cerebral blood volume on perfusion C...
Source: Journal of Stroke and Cerebrovascular Diseases - November 18, 2013 Category: Neurology Authors: Teruyuki Hirano Tags: Review Articles Source Type: research
Utility of Early Post-treatment Single-Photon Emission Computed Tomography Imaging to Predict Outcome in Stroke Patients Treated with Intravenous Tissue Plasminogen Activator
It is important to predict the outcome of tissue plasminogen activator (tPA)–treated patients early after the treatment for considering the post-tPA treatment option. We assessed cerebral blood flow (CBF) of tPA-treated patients with single-photon emission computed tomography (SPECT) 1 hour after tPA infusion to predict the patient outcome. Technetium-99m-hexamethylpropyleneamine oxime SPECT was performed in 35 consecutive tPA-treated patients. Asymmetry index, a contralateral-to-ipsilateral ratio of CBF, was calculated to analyze CBF quantitatively. Hypoperfusion or hyperperfusion was defined as a decrease of 25% or mor...
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2013 Category: Neurology Authors: Takeo Abumiya, Masahito Katoh, Takuya Moriwaki, Masami Yoshino, Takeshi Aoki, Hiroyuki Imamura, Toshimitsu Aida, Hideo Scichinohe, Naoki Nakayama, Ken Kazumata, Kiyohiro Houkin Tags: Original Articles Source Type: research
Quantitative HO-PET in Pediatric Moyamoya Disease: Evaluating Perfusion before and after Cerebral Revascularization
Moyamoya disease (MMD) is an idiopathic intracranial angiopathy with a progressive spontaneous occlusion of the circle of Willis resulting in repeated ischemia if not diagnosed and treated early, especially in children. Prevention of stroke is achieved by revascularization of the affected cerebral regions. Functional imaging techniques such as H2[15O]-Positron emission tomography (PET) allow quantification of cerebral perfusion/blood flow (CBF) and in particular cerebrovascular response after acetazolamide (AZA) challenge.
Source: Journal of Stroke and Cerebrovascular Diseases - March 24, 2015 Category: Neurology Authors: Felix P. Kuhn, Geoff Warnock, Thomas Schweingruber, Michael Sommerauer, Alfred Buck, Nadia Khan Source Type: research
Limited versus Whole-Brain Perfusion for the Indication of Thrombolysis in the Extended Time Window of Acute Cerebral Ischemia
Perfusion computed tomography (PCT) has emerged as alternative to magnetic resonance imaging (MRI) for assessment of patients clinically qualifying for off-label thrombolysis within 4.5 to 9 hours after onset of ischemic stroke. However, disadvantage of PCT is its often limited anatomic coverage with only 2 or 3 slices when using a 4- to 64-section scanner. Our purpose was therefore to evaluate the value of 2- and 3-slice perfusion compared to whole-brain perfusion.
Source: Journal of Stroke and Cerebrovascular Diseases - September 12, 2015 Category: Neurology Authors: Lorenz Breuer, Michael Knott, Tobias Struffert, Stephan Kloska, Natalia Kurka, Stefan Schwab, Arnd Dörfler, Martin Köhrmann, Tobias Engelhorn Source Type: research
Cerebral White Matter Hypoperfusion Increases with Small-Vessel Disease Burden. Data From the Third International Stroke Trial
Leukoaraiosis is associated with impaired cerebral perfusion, but the effect of individual and combined small-vessel disease (SVD) features on white matter perfusion is unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - March 14, 2017 Category: Neurology Authors: Francesco Arba, Grant Mair, Trevor Carpenter, Eleni Sakka, Peter A.G. Sandercock, Richard I. Lindley, Domenico Inzitari, Joanna M. Wardlaw, IST-3 Trial Collaborators Source Type: research
The association between time to recanalization and clinical outcomes depends on pre-treatment cerebral blood volume in endovascular therapy for acute ischemic stroke
【Background and Purpose】Faster times to recanalization improve clinical outcomes in patients after endovascular thrombectomy. Whether the association between time to recanalization and clinical outcomes depends on cerebral blood volume (CBV) obtained from pre-treatment CT perfusion (CTP) was inv estigated.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Tomohide Yoshie, Toshihiro Ueda, Tatsuro Takada, Shinji Nogoshi, Satoshi Takaishi, Ryouo Yamamoto, Takayuki Fukano, Daiki Tokuura, Kentaro Tatsuono Source Type: research
CT perfusion may reveal Todd's paralysis as a stroke mimic?
【Background】Brain perfusion changes have been detected in patients following epileptic seizures.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: David Orion, Shahar Shelly, Nicola Maggio, Marina Boxer Source Type: research
Acute Hearing Loss Caused by Decreasing Anterior Inferior Cerebellar Arterial Perfusion in a Patient with Vertebral Artery Stenosis
We report a case of bilateral hearing loss caused by decreased vascular flow in the anterior inferior cerebellar artery (AICA) territory. A 74-year-old man who experienced right hearing loss 5 months ago presented with bilateral deafness and right cerebellar ataxia; however, no ischemic lesion was detected in the bilateral AICA area. After stroke treatment, hearing loss was improved. One month later, we obtained blood flow improvement in the left AICA territory on single –photon-emission computed tomography and vertebral artery stenosis on magnetic resonance angiography.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2017 Category: Neurology Authors: Rintaro Fukuda, Nobukazu Miyamoto, Arisa Hayashida, Yuji Ueno, Kazuo Yamashiro, Ryota Tanaka, Nobutaka Hattori Tags: Case Studies Source Type: research
Positional Brain Single-Photon Emission Computed Tomography Findings in a Case of Limb-Shaking Syndrome
An 84-year-old man, who presented lower limbs limb-shaking syndrome at orthostatism lasting a few seconds, was referred in our stroke unit. Magnetic resonance imaging showed an acute infarction in the right thalamus and the insular cortex, left extracranial carotid stenosis at 80%, and low flow in the right middle cerebral artery but did not explain limb-shaking syndrome symptomatology. We performed comparative positional brain perfusion single-photon emission computed tomography (SPECT), in the upright and in the supine position, to explore and localize hypoperfusion-endangered brain structures that may be involved in the...
Source: Journal of Stroke and Cerebrovascular Diseases - December 4, 2017 Category: Neurology Authors: Caroline Bund, C éline Heimburger, Valérie Wolff, Izzie Jacques Namer Tags: Case Report Source Type: research
Effects of Pretreatment Cerebral Blood Volume and Time to Recanalization on Clinical Outcomes in Endovascular Thrombectomy for Acute Ischemic Stroke
Faster time to recanalization leads to better clinical outcomes in patients treated with endovascular thrombectomy. Whether the association between time to recanalization and clinical outcomes depends on cerebral blood volume (CBV) obtained from pretreatment computed tomography (CT) perfusion (CTP) imaging was investigated.
Source: Journal of Stroke and Cerebrovascular Diseases - March 7, 2018 Category: Neurology Authors: Tomohide Yoshie, Toshihiro Ueda, Tatsuro Takada, Shinji Nogoshi, Fumio Miyashita, Satoshi Takaishi, Takayuki Fukano, Daiki Tokuura, Yasuhiro Hasegawa Source Type: research
Positional Brain Single-Photon Emission Computed Tomography Findings in a Case of Limb-Shaking Syndrome
An 84-year-old man, who presented lower limbs limb-shaking syndrome at orthostatism lasting a few seconds, was referred in our stroke unit. Magnetic resonance imaging showed an acute infarction in the right thalamus and the insular cortex, left extracranial carotid stenosis at 80%, and low flow in the right middle cerebral artery but did not explain limb-shaking syndrome symptomatology. We performed comparative positional brain perfusion single-photon emission computed tomography (SPECT), in the upright and in the supine position, to explore and localize hypoperfusion-endangered brain structures that may be involved in the...
Source: Journal of Stroke and Cerebrovascular Diseases - December 4, 2017 Category: Neurology Authors: Caroline Bund, C éline Heimburger, Valérie Wolff, Izzie Jacques Namer Tags: Case Report Source Type: research
Single-Centre Experience with Patients Selection for Mechanical Thrombectomy Based on Automated Computed Tomography Perfusion Analysis –A Comparison with Computed TomographyCT Perfusion Thrombectomy Trials
We present a single-center experience with CTP selection and comparison with CTP trials. Methods: Data of consecutive MT patients (from January 2016 to December 2017) were retrospectively reviewed. All patients with multiphase CT angiography confirmed the presence of anterior circulation large vessel occlusion/s in the intracranial internal carotid artery and/or middle cerebral artery (M1 or M2) and with admission brain CTP analyzed by RAPID software were included into the analysis.
Source: Journal of Stroke and Cerebrovascular Diseases - January 14, 2019 Category: Neurology Authors: Jiri Vanicek, Petra Cimflova, Martin Bulik, Jiri Jarkovsky, Veronika Prelecova, Viktor Szeder, Ondrej Volny Source Type: research
Improving Prognostic Evaluation by 4D CTA for Endovascular Treatment in Acute Ischemic Stroke Patients: A Preliminary Study
Objective: We aim to use 4D CTA with a comprehensive and objective scoring system to assess collateral circulation, and explore the value of prognosis prediction in endovascular treated patients. Methods: Thirty-four patients with unilateral anterior circulation large vessels occlusion were reviewed in this study retrospectively. Single-phase CTA (sCTA) and 4D CTA acquired by CT perfusion scanning were analyzed for collateral circulation assessment. The collateral vessels were scored 0-4 according to modified collateral circulation scoring based on 4D CTA.
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2019 Category: Neurology Authors: Ruoyao Cao, Peng Qi, Yinhong Liu, Xinxin Ma, Zhengyin Shen, Juan Chen Source Type: research
