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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 349 results found since Jan 2013.
Cerebral Microbleeds and Chronic Kidney Disease in Acute Ischemic Stroke Patients with Atrial Fibrillation
Background: Cerebral microbleeds (CMBs) are associated with the risk of intracerebral hemorrhage in stroke patients with atrial fibrillation (AF). We investigated the association between CMBs and chronic kidney disease (CKD) in patients with acute ischemic stroke and AF. Methods: We retrospectively examined consecutive patients with acute ischemic stroke and AF who underwent brain gradient-echo T2*-weighted magnetic resonance imaging. The number and distribution (lobar, deep or infratentorial, and mixed) of CMBs were assessed.
Source: Journal of Stroke and Cerebrovascular Diseases - February 2, 2020 Category: Neurology Authors: Kazuo Yamashiro, Ryota Tanaka, Naohide Kurita, Yuji Ueno, Nobukazu Miyamoto, Kenichiro Hira, Sho Nakajima, Takao Urabe, Nobutaka Hattori Source Type: research
Racial-Ethnic Differences in Lacunar Infarction in a Multiethnic Stroke Population
This study examined racial-ethnic differences in the clinical presentation and imaging findings of a racially-ethnically diverse population with acute LIs. Patients with acute LIs were identified over a 3-year period. Baseline clinical characteristics, vascular risk factors, and magnetic resonance imaging findings were analyzed. Comparisons were made between African Americans, Caribbean blacks, Caribbean Hispanics, and non-Hispanic whites. During the study period, 1036 patients with ischemic stroke were admitted, 194 of whom (25%) had a LI. The proportion of LI was the highest in Caribbean blacks (40%) and lowest in non-Hi...
Source: Journal of Stroke and Cerebrovascular Diseases - August 8, 2011 Category: Neurology Authors: Sebastian Koch, Ritu Gupta, Mark S. McClendon, Jose G. Romano Tags: Original Articles Source Type: research
Stroke and Cardio-ankle Vascular Stiffness Index
Background: We investigated the relationship between stroke and cardio-ankle vascular stiffness index (CAVI), a novel noninvasive measure of vascular stiffness.Methods: Eighty-five patients with cerebrovascular disease who underwent CAVI were enrolled in the current study. They were 63 men and 22 women with a mean age of 70.0 ± 10.8 years. They were divided into 4 groups according to neurologic abnormalities and magnetic resonance imaging (MRI) findings: 12 with transient ischemic attack (TIA), 26 with white matter ischemic lesions (WMLs), 17 with large artery atherosclerosis, and 30 with small vessel occlusion. Eight hun...
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2011 Category: Neurology Authors: Jun Suzuki, Ryuji Sakakibara, Takanobu Tomaru, Fuyuki Tateno, Masahiko Kishi, Emina Ogawa, Takumi Kurosu, Kohji Shirai Tags: Original Articles Source Type: research
Validating Imaging Biomarkers of Cerebral Edema in Patients With Severe Ischemic Stroke
Background: There is no validated neuroimaging marker for quantifying brain edema. We sought to test whether magnetic resonance imaging (MRI)–based metrics would reliably change during the early subacute period in a manner consistent with edema and whether they would correlate with relevant clinical endpoints.Methods: Serial MRI studies from patients in the Echoplanar Imaging Thrombolytic Evaluation Trial with initial diffusion-weighted imaging (DWI) lesion volume>82 cm3 were analyzed. Two independent readers outlined the hemisphere and lateral ventricle on the involved side and calculated respective volumes at baseline...
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2012 Category: Neurology Authors: Albert J. Yoo, Kevin N. Sheth, W. Taylor Kimberly, Zeshan A. Chaudhry, Jordan J. Elm, Sven Jacobson, Stephen M. Davis, Geoffrey A. Donnan, Gregory W. Albers, Barney J. Stern, R. Gilberto González Tags: Original Articles Source Type: research
Comparison of CT and DWI Findings in Ischemic Stroke Patients within 3 Hours of Onset
This study compared the detection rate of ischemic lesions within 3 hours of onset by computed tomography (CT) and diffusion-weighted magnetic resonance imaging (DWI). The study group comprised 130 patients (71 men; median age, 75 years) with an anterior territory stroke who underwent CT and DWI within 3 hours of onset. The lesions revealed on CT and DWI were assessed using the CT–Alberta Stroke Program Early CT Score (ASPECTS) and DWI-ASPECTS, and detection rates were compared for each ASPECTS region. The detection rate of ischemic lesions was higher on DWI than on CT (76.9% v 30.0%; P
Source: Journal of Stroke and Cerebrovascular Diseases - October 8, 2012 Category: Neurology Authors: Mutsumi Mitomi, Kazumi Kimura, Junya Aoki, Yasuyuki Iguchi Tags: Original Articles Source Type: research
Clinical Use of Computed Tomographic Perfusion for the Diagnosis and Prediction of Lesion Growth in Acute Ischemic Stroke
Conclusions: In real-world use, acute imaging with CTP did not predict stroke or DWI lesions with sufficient accuracy. Our findings argue against the use of CTP for screening AIS patients until real-world implementations match the accuracy reported from specialized research centers.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Branko N. Huisa, William P. Neil, Ronald Schrader, Marcel Maya, Benedict Pereira, Nhu T. Bruce, Patrick D. Lyden Tags: Original Articles Source Type: research
Nascent Deep Microbleeds and Stroke Recurrences
This study investigated the contributions of nascent deep MBs to stroke recurrence.Methods: We prospectively analyzed nascent deep MBs in patients admitted to our hospital who were treated for index strokes between April 2004 and November 2009. The number of nascent deep MBs was counted on T2∗-weighted MRI scans around 1 year after the index strokes, and compared to previous MRIs on admission. Stroke recurrence–free rate curves were generated using the Kaplan–Meier method using the log-rank test. The odds ratio for nascent deep MBs was derived using a multivariate logistic regression model that was based on recurren...
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Toshio Imaizumi, Shigeru Inamura, Ikuhide Kohama, Kazuhisa Yoshifuji, Tatsufumi Nomura, Katsuya Komatsu Tags: Original Articles Source Type: research
Motion Perception without Nystagmus—A Novel Manifestation of Cerebellar Stroke
Conclusions: This study discovered a novel presentation of cerebellar stroke where only motion perception was affected, but there was an absence of objective neurologic signs.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2013 Category: Neurology Authors: Aasef G. Shaikh Tags: Original Articles Source Type: research
White Matter Hyperintensity Volume Correlates with Matrix Metalloproteinase-2 in Acute Ischemic Stroke
Background: White matter hyperintensity (WMH), a common radiographic finding associated with stroke risk and outcome, has been linked to matrix metalloproteinase (MMP) activity and increased levels of oxidative stress in nonstroke populations. We sought to determine whether WMH severity is associated with plasma levels of MMPs and oxidative stress (F2-isoprostane) in subjects with acute ischemic stroke (AIS).Methods: We measured plasma biomarker levels at baseline and 48 hours in consecutive AIS subjects. White matter hyperintensity volume (WMHv) was quantified on admission magnetic resonance imaging using a validated sem...
Source: Journal of Stroke and Cerebrovascular Diseases - January 21, 2014 Category: Neurology Authors: Zachary A. Corbin, Natalia S. Rost, Svetlana Lorenzano, Walter N. Kernan, Michael K. Parides, Jeffrey B. Blumberg, Paul E. Milbury, Ken Arai, Sophia N. Hartdegen, Eng H. Lo, Steven K. Feske, Karen L. Furie Tags: Original Articles Source Type: research
Crossed Cerebellar Diaschisis Detected by Arterial Spin-Labeled Perfusion Magnetic Resonance Imaging in Subacute Ischemic Stroke
Conclusions: With advantages in easy acquisition and no radiation, ASL-MRI seems to be an ideal tool for the detection and follow-up of CCD.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Shuai Chen, Min Guan, Hao-Jun Lian, Li-Jia Ma, Jun-Kui Shang, Shuang He, Ming-Ming Ma, Mi-Lan Zhang, Zi-Yuan Li, Mei-Yun Wang, Da-Peng Shi, Jie-Wen Zhang Tags: Original Articles Source Type: research
A Systemized Stroke Code Significantly Reduced Time Intervals for using Intravenous Tissue Plasminogen Activator under Magnetic Resonance Imaging Screening
A stroke code can shorten time intervals until intravenous tissue plasminogen activator (IV t-PA) treatment in acute ischemic stroke (AIS). Recently, several reports demonstrated that magnetic resonance imaging (MRI)–based thrombolysis had reduced complications and improved outcomes in AIS despite longer processing compared with computed tomography (CT)–based thrombolysis.
Source: Journal of Stroke and Cerebrovascular Diseases - December 15, 2014 Category: Neurology Authors: Sang-Wook Sohn, Hyun-Seok Park, Jae-Kwan Cha, Hyun-Wook Nah, Dae-Hyun Kim, Myong-Jin Kang, Jae-Hyung Choi, Jae-Taeck Huh Source Type: research
Noncardiogenic Stroke Patients with Metabolic Syndrome Have More Border-zone Infarction and Intracranial Artery Stenosis
Little is known about the clinical character of stroke patients with metabolic syndrome (MetS) in Chinese population. In this hospital-based cross-sectional study, we elucidated the prevalence of MetS among patients with acute noncardiogenic cerebral infarction from south China, the topographic infarction patterns in magnetic resonance imaging, and vascular angiography findings of stroke patients with MetS.
Source: Journal of Stroke and Cerebrovascular Diseases - January 2, 2015 Category: Neurology Authors: Zheng Zhang, Meijuan Xiao, Zusen Ye, Wanli Zhang, Bin Han, Youcheng Li Source Type: research
A Case of Recurrent Ischemic Stroke Involving Subacute, Progressive Intracranial Cerebral Arterial Sclerosis Prior to Diagnosis with -mutated Polycythemia Vera
A 58-year-old man presenting with no vascular risk factors visited our hospital with right hemiparesis and total aphasia. Diffusion-weighted magnetic resonance imaging of the brain showed multiple hyperintensities in watershed distributions in the left hemisphere. Magnetic resonance angiography (MRA) revealed stenosis of the middle cerebral artery, despite normal MRA findings 2 months prior. One year after the first stroke, the patient experienced a recurrent ischemic stroke involving the left anterior choroidal artery, pulmonary embolism, and deep venous thrombosis.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2015 Category: Neurology Authors: Tomohisa Nezu, Shiro Aoki, Kazuhide Ochi, Sayaka Sugihara, Tetsuya Takahashi, Naohisa Hosomi, Hirofumi Maruyama, Masayasu Matsumoto Tags: Case Studies Source Type: research
A Simple Geometric Assessment of Perfusion Lesion Volume at Hyperacute Stage of Ischemic Stroke in Patients with Symptomatic Steno-Occlusion of Major Cerebral Arteries and Risk of Subsequent Cerebral Ischemic Events
Our objective is to elucidate the association of baseline perfusion lesion volume on perfusion-weighted magnetic resonance imaging (PWI) obtained at hyperacute stage of ischemic stroke with subsequent cerebral ischemic events (SIEs) in patients with symptomatic steno-occlusion of major cerebral arteries. Using a prospective stroke registry database, patients arriving within 24 hours of onset with symptomatic steno-occlusion of major supratentorial cerebral arteries were identified. On baseline PWI, time-to-peak lesion volume (TTP-LV) was determined by a simple geometric method and dichotomized into the highest tertile (la...
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2015 Category: Neurology Authors: Jihoon Kang, Cheolkyu Jung, Nayoung Kim, Yoo Ri Son, Byungse Choi, Jae-Hyoung Kim, Ji Sung Lee, Juneyoung Lee, Jun Lee, Myung Suk Jang, Mi Hwa Yang, Moon-Ku Han, Hee-Joon Bae Source Type: research
Early Magnetic Resonance Imaging Predicts Early Neurological Deterioration in Acute Middle Cerebral Artery Minor Stroke
Early neurological deterioration (END) is an important factor associated with worse clinical outcome in minor strokes. Early magnetic resonance imaging (MRI) findings can provide better sensitivity to delineate stroke pathophysiology and have diagnostic value associated with causative mechanisms. The aim of this study was to investigate the relationship between early MRI finding and the presence of END in minor stroke patients with lesions in the middle cerebral artery (MCA) territory.
Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2015 Category: Neurology Authors: Dezhi Liu, Wen Sun, Fabien Scalzo, Yunyun Xiong, Xiaohao Zhang, Zhongming Qiu, Wusheng Zhu, Minmin Ma, Wenhua Liu, Gelin Xu, Guangming Lu, David S. Liebeskind, Xinfeng Liu Source Type: research
