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Mechanism of Acute Ischemic Stroke in Patients with Severe Middle Cerebral Artery Atherosclerotic Disease
Conclusions: In patients with severe MCA ICAD, the mechanism of stroke is multifactorial, but hemodynamic insufficiency plays a significant role. This finding is important in selecting a subgroup of patients who may benefit from revascularization.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2014 Category: Neurology Authors: Jordan S. Dubow, Elliott Salamon, Edward Greenberg, Athos Patsalides Tags: Original Articles Source Type: research

Evaluating Middle Cerebral Artery Atherosclerotic Lesions in Acute Ischemic Stroke Using Magnetic Resonance T1-weighted 3-Dimensional Vessel Wall Imaging
Background: Atherosclerotic lesions in intracranial arteries are a leading cause of ischemic stroke. Magnetic resonance angiography (MRA) is often used to assess atherosclerotic changes by detecting luminal narrowing, whereas it cannot directly visualize atherosclerotic lesions. Here, we used a 3-dimensional vessel wall imaging (3D-VWI) technique to evaluate intracranial arterial wall changes in acute stroke.Methods: Eighteen consecutive patients with acute noncardioembolic stroke in the middle cerebral artery (MCA) territory who were prospectively examined with a 1.5-T magnetic resonance scanner were studied. T1-weighted ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 22, 2013 Category: Neurology Authors: Tatsunori Natori, Makoto Sasaki, Mitsuharu Miyoshi, Hideki Ohba, Noriyuki Katsura, Mao Yamaguchi, Shinsuke Narumi, Hiroyuki Kabasawa, Kohsuke Kudo, Kenji Ito, Yasuo Terayama Tags: Original Articles Source Type: research

Determinants of White Matter Hyperintensity Burden Differ at the Extremes of Ages of Ischemic Stroke Onset
Age is a well-known risk factor for both stroke and increased burden of white matter hyperintensity (WMH), as detected on magnetic resonance imaging (MRI) scans. However, in patients diagnosed with ischemic stroke (IS), WMH volume (WMHv) varies significantly across age groups. We sought to examine the determinants of WMH burden across the ages of stroke onset with the goal to uncover potential age-specific stroke prevention targets.
Source: Journal of Stroke and Cerebrovascular Diseases - January 6, 2015 Category: Neurology Authors: Cathy R. Zhang, Lisa Cloonan, Kaitlin M. Fitzpatrick, Allison S. Kanakis, Alison M. Ayres, Karen L. Furie, Jonathan Rosand, Natalia S. Rost Source Type: research

Recurrent Stroke and Early Mortality in an Urban Medical Unit in Cameroon
Data on stroke mortality in recurrent strokes in the context of limited acute stroke care and secondary stroke prevention within Africa are very scant. We investigated the risk of in-hospital death in patients with recurrent stroke in the medical department of the Yaound é Central Hospital in Cameroon.
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2017 Category: Neurology Authors: Alain Lekoubou, Clovis Nkoke, Anastase Dzudie, Andre Pascal Kengne Source Type: research

“No Turn Back Approach” to Reduce Treatment Time for Endovascular Treatment of Acute Ischemic Stroke
Conclusions: The no turn back approach appeared to be feasible and reduced the time interval between ED arrival and microcatheter placement in acute ischemic stroke patients undergoing endovascular treatment.
Source: Journal of Stroke and Cerebrovascular Diseases - February 21, 2014 Category: Neurology Authors: Adnan I. Qureshi, Hossam Egila, Malik M. Adil, Harris Siddiqi, Nidaullah Mian, Ameer E. Hassan, Jefferson T. Miley, Gustavo J. Rodriguez, M. Fareed K. Suri Tags: Original Articles Source Type: research

Predicting Stroke Outcome Using Clinical- versus Imaging-based Scoring System
Several models to predict outcome in ischemic stroke patients receiving intravenous (i.v.) alteplase can be divided into clinical-based and imaging-based systems. Alberta Stroke Program Early Computed Tomography (CT) Score (ASPECTS) and Dense cerebral artery sign/early infarct signs on admission CT scan, prestroke modified Rankin Scale (mRS) score, Age, Glucose level at baseline, Onset-to-treatment time, and baseline National Institutes of Health Stroke Scale score (DRAGON) are typical imaging- and clinical-based scoring systems, respectively.
Source: Journal of Stroke and Cerebrovascular Diseases - January 6, 2015 Category: Neurology Authors: Joon Hyun Baek, Kitae Kim, Yeong-Bae Lee, Kee-Hyung Park, Hyeon-Mi Park, Dong-Jin Shin, Young Hee Sung, Dong Hoon Shin, Oh Young Bang Source Type: research

Visual Determination of Conjugate Eye Deviation on Computed Tomography Scan Predicts Diagnosis of Stroke Code Patients
Head computed tomography (CT) is critical for stroke code evaluations and often happens prior to completion of the neurological exam. Eye deviation on neuroimaging (DeyeCOM sign) has utility for predicting stroke diagnosis and correlates with National Institutes of Health Stroke Scale (NIHSS) gaze score. We further assessed the utility of the DeyeCOM sign, without complex caliper-based eye deviation calculations, but simply with a visual determination method.
Source: Journal of Stroke and Cerebrovascular Diseases - August 26, 2016 Category: Neurology Authors: Ilana Spokoyny, James Y. Chen, Rema Raman, Karin Ernstrom, Kunal Agrawal, Royya F. Modir, Dawn M. Meyer, Brett C. Meyer Source Type: research

Spinal epidural hematoma as a stroke mimic
Spinal epidural hematoma is a rare disease with an annual incidence of 1 per 1,000,000 individuals;1 however, it is a critical stroke mimic.2 As patients with spinal epidural hematoma typically present with acute hemiparesis,3,4 such a presentation is not expected to be detected by a computed tomography (CT) scan of the brain, which is the most common neuroimaging choice in patients with an activated stroke code. Indeed, there are several case reports in which patients with spinal epidural hematoma were misdiagnosed with ischemic stroke and treated with anti-thrombotic therapy, including intravenous thrombolysis,5 –10 oc...
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Yuichiro Inatomi, Makoto Nakajima, Toshiro Yonehara Source Type: research

Diagnostic and Prognostic Blood Biomarkers in Transient Ischemic Attack and Minor Ischemic Stroke: An Up-To-Date Narrative Review
Transient ischemic attack (TIA) is a brief episode of focal neurological deficit, lasting less than 24 hours, and reaching its climax usually within minutes. Patients with an even tiny ischemic brain lesion on imaging are considered, on tissue-based criteria, to have a minor ischemic stroke (MIS), usually with mild and non-disabling symptoms.1 Although a consensus clinical definition for MIS is currently lacking, 5 working definitions based on information from head computed tomography (CT) scan and clinical examination have been developed by the National Institute of Neurological Disorder and Stroke (NINDS) rt-PA stroke study Investigators.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2022 Category: Neurology Authors: Matteo Foschi, Marina Padroni, Samir Abu-Rumeileh, Ahmed Abdelhak, Michele Russo, Lucio D'Anna, Maria Guarino Tags: Review Article Source Type: research

Time to ct scan imaging after symptom onset among ischeamic stroke patients presenting to a quaternary hospital in ghana
This study sought to determine the time of onset of symptoms to the time a CT imaging was done among patients presenting with acute stroke at the Korle-Bu Teaching Hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: F. Duodu, D. Brodie Mends, B. Agbinko-Djobalar, P. Pekyi-Boateng, M. Amerwornu, P Adjei, A Akpalu, K Nkromah Source Type: research

Validating Imaging Biomarkers of Cerebral Edema in Patients With Severe Ischemic Stroke
Background: There is no validated neuroimaging marker for quantifying brain edema. We sought to test whether magnetic resonance imaging (MRI)–based metrics would reliably change during the early subacute period in a manner consistent with edema and whether they would correlate with relevant clinical endpoints.Methods: Serial MRI studies from patients in the Echoplanar Imaging Thrombolytic Evaluation Trial with initial diffusion-weighted imaging (DWI) lesion volume>82 cm3 were analyzed. Two independent readers outlined the hemisphere and lateral ventricle on the involved side and calculated respective volumes at baseline...
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2012 Category: Neurology Authors: Albert J. Yoo, Kevin N. Sheth, W. Taylor Kimberly, Zeshan A. Chaudhry, Jordan J. Elm, Sven Jacobson, Stephen M. Davis, Geoffrey A. Donnan, Gregory W. Albers, Barney J. Stern, R. Gilberto González Tags: Original Articles Source Type: research

The Essential Can Be Invisible to the Eyes: The “Fogging Effect” Phenomenon in the Subacute Stage of Ischemic Stroke
We report a patient who presented with a vanishing stroke on a follow-up brain computed tomography scan, a condition known as the “fogging effect” phenomenon.
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2012 Category: Neurology Authors: Irapuá Ferreira Ricarte, José Luiz Pedroso, Flávio Augusto Carvalho, Agessandro Abrahão, Raul Alberto Valiente, Maramélia Miranda Alves, Daniela Laranja Gomes, Gisele Sampaio Silva Tags: Case Reports Source Type: research

Nascent Deep Microbleeds and Stroke Recurrences
This study investigated the contributions of nascent deep MBs to stroke recurrence.Methods: We prospectively analyzed nascent deep MBs in patients admitted to our hospital who were treated for index strokes between April 2004 and November 2009. The number of nascent deep MBs was counted on T2∗-weighted MRI scans around 1 year after the index strokes, and compared to previous MRIs on admission. Stroke recurrence–free rate curves were generated using the Kaplan–Meier method using the log-rank test. The odds ratio for nascent deep MBs was derived using a multivariate logistic regression model that was based on recurren...
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Toshio Imaizumi, Shigeru Inamura, Ikuhide Kohama, Kazuhisa Yoshifuji, Tatsufumi Nomura, Katsuya Komatsu Tags: Original Articles Source Type: research

Investigating the Utility of Previously Developed Prediction Scores in Acute Ischemic Stroke Patients in the Stroke Belt
Conclusions: Our study demonstrated that although highly predictive of outcome in the original study design treatment groups, prediction scores may not generalize to all patient samples, highlighting the importance of validating prediction scores in diverse samples.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2014 Category: Neurology Authors: Amelia K. Boehme, Pawan V. Rawal, Michael J. Lyerly, Karen C. Albright, Reza Bavarsad Shahripour, Paola Palazzo, Niren Kapoor, Mohammad Alvi, J. Thomas Houston, Mark R. Harrigan, Luis Cava, April Sisson, Anne W. Alexandrov, Andrei V. Alexandrov Tags: Original Articles Source Type: research

Crossed Cerebellar Diaschisis Detected by Arterial Spin-Labeled Perfusion Magnetic Resonance Imaging in Subacute Ischemic Stroke
Conclusions: With advantages in easy acquisition and no radiation, ASL-MRI seems to be an ideal tool for the detection and follow-up of CCD.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Shuai Chen, Min Guan, Hao-Jun Lian, Li-Jia Ma, Jun-Kui Shang, Shuang He, Ming-Ming Ma, Mi-Lan Zhang, Zi-Yuan Li, Mei-Yun Wang, Da-Peng Shi, Jie-Wen Zhang Tags: Original Articles Source Type: research

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