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Posterior Circulation Hyperperfusion Syndrome after Superficial Temporal Artery–Superior Cerebellar Artery Bypass for Vertebral Artery Dissection
We report the first case of posterior circulation hyperperfusion syndrome after STA–SCA bypass and provide a review of the relevant literature.
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2013 Category: Neurology Authors: Kenji Fukuda, Hiroshi Abe, Tetsuya Ueba, Masakazu Okawa, Toshio Higashi, Tooru Inoue Tags: Case Reports Source Type: research

Combined Treatment of Methylprednisolone Pulse and Memantine Hydrochloride Prompts Recovery from Neurological Dysfunction and Cerebral Hypoperfusion in Carbon Monoxide Poisoning: A Case Report
A 49-year-old healthy man developed sudden unconsciousness under inadequate ventilation. Blood gas analysis showed carboxyhemoglobin of 7.3%. After normobaric oxygen therapy, he recovered completely 7 days later. At 3 weeks after carbon monoxide (CO) exposures, memory and gait disturbances appeared. Neurological examination revealed Mini-Mental State Examination (MMSE) score of 5 of 30 points, leg hyper-reflexia with Babinski signs, and Parkinsonism. Brain fluid-attenuated inversion recovery imaging disclosed symmetric hypointense lesions in the thalamus and the globus pallidus, and hyperintense lesions in the cerebral w...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2013 Category: Neurology Authors: Konosuke Iwamoto, Ken Ikeda, Sunao Mizumura, Kazuhiro Tachiki, Masaru Yanagihashi, Yasuo Iwasaki Tags: Case Reports Source Type: research

A Case of Bilateral Giant Internal Carotid Artery Aneurysms at the Cavernous Portion Managed by 2-stage Extracranial–Intracranial Bypass with Parent Artery Occlusion: Consideration for Bypass Selection and Timing of Surgeries
In conclusion, high-flow EC-IC bypass with PAO is recommended in the first stage of surgery on a unilaterally symptomatic side to minimize postoperative hemodynamic stress to the contralateral aneurysm. Once the contralateral side becomes symptomatic, second stage EC-IC bypass with PAO, either low-flow or high-flow bypass, is recommended based on the results of balloon test occlusion.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Miki Fujimura, Kenichi Sato, Naoto Kimura, Takashi Inoue, Hiroaki Shimizu, Teiji Tominaga Tags: Case Reports Source Type: research

Efficacy of Extracranial–Intracranial Bypass for Progressive Middle Cerebral Artery Occlusion Associated with Active Sjögren's Syndrome: Case Report
Sjögren syndrome affecting the major cerebral arteries is rare, and an optimal therapeutic strategy to counteract such a lesion has not yet been established. We herein report a case of a 39-year-old woman with a history of primary Sjögren syndrome, which had previously been treated with immunosuppressive therapy, manifesting with a crescendo transient ischemic attack because of left middle cerebral artery stenosis. Despite the administration of high doses of prednisolone and azathioprine for active Sjögren syndrome, the frequency of crescendo transient ischemic attacks increased with the progression of stenosis and magn...
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Hiroyuki Sakata, Miki Fujimura, Kenichi Sato, Hiroaki Shimizu, Teiji Tominaga Tags: Case Reports Source Type: research

Arterial Spin Labeling Perfusion Magnetic Resonance Image with Dual Postlabeling Delay: A Correlative Study with Acetazolamide Loading I-Iodoamphetamine Single-Photon Emission Computed Tomography
Perfusion magnetic resonance image with arterial spin labeling (ASL) provides a completely noninvasive measurement of cerebral blood flow (CBF). However, arterial transient times can have a marked effect on the ASL signal. For example, a single postlabeling delay (PLD) of 1.5 seconds underestimates the slowly streaming collateral pathways that maintain the cerebrovascular reserve (CVR). To overcome this limitation, we developed a dual PLD method.
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2015 Category: Neurology Authors: Sei Haga, Takato Morioka, Takafumi Shimogawa, Tomoaki Akiyama, Kei Murao, Yuka Kanazawa, Tetsuro Sayama, Shuji Arakawa Source Type: research

Assessment of Hemodynamic Compromise Using Computed Tomography Perfusion in Combination with 123I-IMP Single-Photon Emission Computed Tomography without Acetazolamide Challenge Test
In this study, we investigated whether CT perfusion in combination with resting state 123I-IMP SPECT could be used instead of the acetazolamide challenge test to evaluate hemodynamic compromise in patients with atherosclerotic occlusive disease.
Source: Journal of Stroke and Cerebrovascular Diseases - December 5, 2016 Category: Neurology Authors: Atsumu Hashimoto, Takeshi Mikami, Katsuya Komatsu, Shouhei Noshiro, Tohru Hirano, Masahiko Wanibuchi, Nobuhiro Mikuni Source Type: research

Progressive Cerebral Ischemia and Intracerebral Hemorrhage after Indirect Revascularization for a Patient with Cerebral Proliferative Angiopathy
We previously reported a patient with cerebral proliferative angiopathy (CPA) who showed cerebral ischemia in resting and acetazolamide-stressed N-isopropyl-p-[123I] iodoamphetamine single-photon emission computed tomography (123I-IMP-SPECT). At onset, the patient was treated conservatively. However, during the 2 years following initial onset, his hemiparesis and aphasia had gradually aggravated and his IQ scores were markedly decreased. MRI revealed progressive vascular proliferation and brain atrophy.
Source: Journal of Stroke and Cerebrovascular Diseases - February 6, 2019 Category: Neurology Authors: Tomomi Kimiwada, Toshiaki Hayashi, Misaki Takahashi, Reizo Shirane, Teiji Tominaga Source Type: research

Anterior Choroidal Artery Infarction Evaluated with 123I-Imp Single-Photon Emission Computed Tomography and 7 Tesla Magnetic Resonance Imaging
Anterior choroidal artery (AchA) infarction remains a challenging diagnosis although it was first described almost 100 years prior. N-isopropyl-p-[123I]-iodoamphetamine single-photon emission computed tomography (123I-IMP SPECT) and 7 Tesla magnetic resonance angiography (7T-MRA) are not routinely performed in cases of AchA infarction. Therefore, the application of 123I-IMP SPECT and 7T-MRA for AchA infarction has not been reported previously. A 67-year-old man presented with disturbed consciousness, gaze preference to the left, aphasia, right homonymous hemianopia, and right hemiparesis.
Source: Journal of Stroke and Cerebrovascular Diseases - March 8, 2019 Category: Neurology Authors: Te-Hsiung Wang, Naoto Jingami, Tomohisa Okada, Tomoyuki Yunoki, Shigeru Ohtsuru, Kaoru Koike Tags: Case Report Source Type: research

A Case of Delayed Intraparenchymal Hemorrhage Due to Hyperperfusion After Flow Diverter Treatment
We present the case of a 54-year-old woman with a partially thrombosed large internal carotid artery aneurysm. She presented intraparenchymal hemorrhage in the right parietal lobe three days after the successful FD treatment. We performed endoscopic hematoma removal, and then her consciousness disturbance was fully recovered. IMP single-photon emission computed tomography showed significant increase of cerebral blood flow in the right hemisphere.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2020 Category: Neurology Authors: Takaaki Itazu, Yukiko Enomoto, Keita Yamauchi, Yusuke Egashira, Toru Iwama Tags: Case Report Source Type: research

Detection of impaired cerebrovascular reactivity in patients with chronic cerebral ischemia using whole-brain 7T MRA
We examined whether whole-brain magnetic resonance angiography (MRA) at 7T could non-invasively detect impaired CVR in patients with chronic cerebral ischemia by demonstrating the leptomeningeal collaterals (LMCs).
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Ikuko Uwano, Hiroyuki Kameda, Taisuke Harada, Masakazu Kobayashi, Wataru Yanagihara, Kengo Setta, Kuniaki Ogasawara, Kunihiro Yoshioka, Fumio Yamashita, Futoshi Mori, Tsuyoshi Matsuda, Makoto Sasaki Source Type: research

Assessment of Impaired Cerebrovascular Reactivity in Chronic Cerebral Ischemia using Intravoxel Incoherent Motion Magnetic Resonance Imaging
The severity of chronic cerebral ischemia can be assessed using cerebrovascular reactivity (CVR) to acetazolamide (ACZ) challenge, which is measured by single-photon emission computed tomography (SPECT); however, this is an invasive method. We investigated whether intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) can assess impaired CVR in preoperative patients with chronic cerebral ischemia and compared it to SPECT-CVR.
Source: Journal of Stroke and Cerebrovascular Diseases - September 23, 2021 Category: Neurology Authors: Ikuko Uwano, Masakazu Kobayashi, Kengo Setta, Kuniaki Ogasawara, Fumio Yamashita, Futoshi Mori, Tsuyoshi Matsuda, Makoto Sasaki Source Type: research

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