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Source: Journal of Stroke and Cerebrovascular Diseases
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Total 317 results found since Jan 2013.

Telemedical Brain Computed Tomography Misinterpretation by Stroke Neurologists Is Not Associated with Thrombolysis-Related Intracranial Hemorrhage
The Stroke Eastern Saxony Network (SOS-NET) provides telecare for acute stroke patients. Stroke neurologists recommend intravenous thrombolysis based on clinical assessment and cerebral computed tomography (CT) evaluation using Alberta Stroke Program Early CT score (ASPECTS). We sought to assess whether ASPECTS misinterpretation by stroke neurologists was associated with thrombolysis-related symptomatic intracranial hemorrhage (sICH).
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2015 Category: Neurology Authors: Charlotte Zerna, Ruediger von Kummer, Johannes Gerber, Kai Engellandt, Andrij Abramyuk, Claudia Wojciechowski, Kristian Barlinn, Jessica Kepplinger, Lars-Peder Pallesen, Timo Siepmann, Imanuel Dzialowski, Heinz Reichmann, Volker Puetz, Ulf Bodechtel Source Type: research

Ischemic Volume and Neurological Deficit: Correlation of Computed Tomography Perfusion with the National Institutes of Health Stroke Scale Score in Acute Ischemic Stroke
The National Institutes of Health Stroke Scale (NIHSS) is the most adopted stroke patients' evaluation tool in emergency settings to assess the severity of stroke and to determine the patients' eligibility for specific treatments. Computed tomography perfusion (CTP) is crucial to identify salvageable tissue that can benefit from the reperfusion treatment. The aim of this study is to identify the relation between the NIHSS scores and the hypoperfused volumes evaluated by CTP in patients with hyperacute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 30, 2018 Category: Neurology Authors: Giovanni Furlanis, Milo š Ajčević, Lara Stragapede, Carlo Lugnan, Mariana Ridolfi, Paola Caruso, Marcello Naccarato, Maja Ukmar, Paolo Manganotti Source Type: research

Cerebral Microbleeds on T2*-Weighted Images and Hemorrhagic Transformation after Antithrombotic Therapies for Ischemic Stroke
In conclusion, the severity of neurological deficits and the ASPECTS-DWI are closely correlated to the development of HT related to anticoagulants/antiplatelets but not to CMBs on T2*-weighted images.
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2013 Category: Neurology Authors: Wakoh Takahashi, Yusuke Moriya, Atsushi Mizuma, Tsuyoshi Uesugi, Yoichi Ohnuki, Shunya Takizawa Tags: Original Articles Source Type: research

Thrombolysis for Acute Ischemic Stroke: Do Patients Treated Out of Hours Have a Worse Outcome?
Introduction: Previous studies on the impact of nonworking hours (NWH) have produced conflicting results. We aimed to compare the time to treatment with thrombolysis between NWH and working hours (WH) at an Australian comprehensive stroke center.Materials and Methods: All acute ischemic stroke patients treated with intravenous alteplase (IV-alteplase) from January 2003 to December 2011 at the Royal Melbourne Hospital were included. Data collected included demographics, serial time points (including onset, presentation to emergency department, neuroimaging, and thrombolysis), and clinical outcomes (modified Rankin Scale [mR...
Source: Journal of Stroke and Cerebrovascular Diseases - April 30, 2013 Category: Neurology Authors: Kun Fang, Leonid Churilov, Louise Weir, Qiang Dong, Stephen Davis, Bernard Yan Tags: Original Articles Source Type: research

Prevalence of Intracranial Stenosis in a Norwegian Ischemic Stroke Population
Conclusions: IS occurs in approximately 10% and is symptomatic in about 7% of a Norwegian ischemic stroke/TIA population. Diabetes mellitus appears to be the major risk factor for IS.
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2014 Category: Neurology Authors: Nicola Logallo, Halvor Naess, Ulrike Waje-Andreassen, Lars Thomassen Tags: Original Articles Source Type: research

Effective Mechanical Thrombectomy in a Patient with Hyperacute Ischemic Stroke Associated with Cardiac Myxoma
We describe a patient with hyperacute stroke caused by cardiac myxoma who had a good outcome with rapid recanalization through mechanical thrombectomy. A 46-year-old man was admitted with acute symptoms of right side hemiplegia and global aphasia. Brain computed tomography (CT) angiography showed a T occlusion of the left internal carotid artery. Intravenous recombinant tissue plasminogen activator was administered. However, his clinical symptoms did not improve. Thus, we performed endovascular treatment and had a successful outcome. A pathologic examination of the retrieved clot revealed a tumor emboli from a cardiac myxo...
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Seol-Hee Baek, Soonchan Park, Nam Joon Lee, Youngjin Kang, Kyung-Hee Cho Tags: Case Reports Source Type: research

The “DeyeCOM Sign”: Predictive Value in Acute Stroke Code Evaluations
Rapid diagnosis in stroke is critical. Computed tomography is often performed initially, even before a neurologic examination. Gaze deviation has been correlated with stroke diagnosis in some cohorts. Conjugate gaze deviation on stroke code imaging, the “DeyeCOM sign,” may have emergency stroke care implications.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2015 Category: Neurology Authors: Clarity R. Coffman, Rema Raman, Karin Ernstrom, Nabeel A. Herial, Konrad H. Schlick, Karen Rapp, Royya F. Modir, Dawn M. Meyer, Thomas M. Hemmen, Brett C. Meyer Source Type: research

Using Radiological Data to Estimate Ischemic Stroke Severity
Risk-adjusted poststroke mortality has been proposed for use as a measure of stroke care quality. Although valid measures of stroke severity (e.g., the National Institutes of Health Stroke Scale [NIHSS]) are not typically available in administrative datasets, radiology reports are often available within electronic health records. We sought to examine whether admission head computed tomography data could be used to estimate stroke severity.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2016 Category: Neurology Authors: Jason J. Sico, Michael S. Phipps, John Concato, Cynthia Brandt, Carolyn K. Wells, Albert C. Lo, Stephen E. Nadeau, Linda S. Williams, Mark Gorman, John L. Boice, Dawn M. Bravata Source Type: research

Comments on Validation of Serial Alberta Stroke Program Early CT Score as an Outcome Predictor in Thrombolyzed Stroke Patients
We were interested to read the article by Kong et  al that was published in the Journal of Stroke and Cerebrovascular Diseases in June 2017.1 The authors aimed to assess the validity of the serial Alberta Stroke Program Early CT Score (ASPECTS) in predicting unfavorable outcomes in thrombolyzed stroke patients. The results have demonstrated that 2 4-hour ASPECTS on computed tomography and change in ASPECTS (between the baseline and 24-hour computed tomography) can predict accurately functional outcome in the patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2017 Category: Neurology Authors: Saeid Safiri, Erfan Ayubi Tags: Letter to the Editor Source Type: research

Does the Primary Imaging Modality —Computed Tomography or Magnetic Resonance Imaging—Influence Stroke Physicians' Certainty on Whether or Not to Give Thrombolysis to Randomized Acute Stroke Patients?
Door-to-needle time of 20 minutes to stroke patients with intravenous tissue plasminogen activator (iv-tPA) is feasible when computed tomography (CT) is used as first-line of brain imaging. Magnetic resonance imaging (MRI)-based assessment is more time-consuming but superior in detecting acute ischemia. The certainty with which stroke physicians prescribe or refrain from giving iv-tPA treatment to CT- versus MRI-examined patients has not previously been studied. The aim of the present study was to determine the effect of a primary imaging strategy of CT or MRI on clinicians' certainty to prescribe or refrain from giving iv...
Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2017 Category: Neurology Authors: Christine Krarup Hansen, Anders Christensen, Helen Rodgers, Inger Havsteen, Christina Kruuse, Hanne Christensen Source Type: research

Early Magnetic Resonance Imaging Decreases Hospital Length of Stay in Patients with Ischemic Stroke
Imaging modalities are important part of stroke evaluation. Noncontrast head computed tomography (CT) is the initial imaging modality in acute stroke and although important to rule out acute hemorrhage and making a decision on thrombolytic treatment, ischemic changes may not be visible on CT for up to 24 hours. Magnetic resonance imaging (MRI) brain is an invaluable tool to confirm an ischemic stroke and facilitates stroke evaluation. Objective of this study was to investigate the correlation between time to MRI and length of hospital stay.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2018 Category: Neurology Authors: Bharti Manwani, Subhendu Rath, Nora S. Lee, Ilene Staff, Christoph Stretz, Janhavi Modak, Pasquale F. Finelli Source Type: research

Large Vessel Occlusion Score: A Screening Tool to Detect Large Vessel Occlusion in the Acute Stroke Setting
Background: The results of recent trials of mechanical thrombectomy for acute ischemic stroke have increased the demand for identification of patients with large vessel occlusion (LVO) at the primary stroke center, where a prompt detection may expedite transfer to a comprehensive stroke center for endovascular treatment. However, in developing countries, a noncontrast computed tomography (NCCT) may be the only neuroimaging modality available at the primary stroke center scenario, what calls for a screening strategy accurate enough to avoid unnecessary transfers of noneligible patients for endovascular therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - December 29, 2018 Category: Neurology Authors: Rui Kleber do V. Martins-Filho, Francisco A. Dias, Frederico F.A. Alves, Millene R. Camilo, Clara M.A. Barreira, Milena C. Libardi, Daniel G. Abud, Octavio M. Pontes-Neto Source Type: research

The Yield of Multimodal Computed Tomography among Emergency Department Patients with Suspected Large Vessel Occlusion Stroke
Objectives: Endovascular therapy (EVT) improves outcomes for appropriately selected acute ischemic stroke patients. Guidelines suggest rapid acquisition of noninvasive vascular imaging to screen suspected ischemic stroke patients for large vessel occlusion (LVO) and candidacy for EVT. We sought to quantify the yield of an LVO stroke screening process in an undifferentiated emergency department (ED) suspected stroke population as well as identify predictors of successful EVT. Methods: We identified a cohort of consecutive ED patients who received CT angiography and brain perfusion (CTA/P) imaging to determine candidacy for EVT during 2016.
Source: Journal of Stroke and Cerebrovascular Diseases - September 3, 2019 Category: Neurology Authors: Yalda Serena Dastmalchi, J. Adam Oostema Source Type: research

Impact of Window Setting Optimization on Accuracy of Computed Tomography and Computed Tomography Angiography Source Image-based Alberta Stroke Program Early Computed Tomography Score
This study analyzed the effect of optimization of window settings on the accuracy of Alberta Stroke Program Early Computed Tomography Score (ASPECTS) performed on noncontrast CT (NCCT) and CT angiography source images (CTA-SI). ASPECTS was calculated on NCCT and CTA-SI with standard and optimized window width/center settings in a consecutive series of patients with acute ishcemic stroke. The difference between CT-based ASPECTS and ASPECTS performed on follow-up magnetic resonance imaging (MRI) were calculated to determine the disparity between initial estimates of the extent of ischemia on CT and follow-up lesion imaging b...
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2012 Category: Neurology Authors: Ethem Murat Arsava, Jukka T. Saarinen, Ali Unal, Erhan Akpinar, Kader K. Oguz, Mehmet Akif Topcuoglu Tags: Original Articles Source Type: research

Internal Cerebral Vein Asymmetry on Follow-up Brain Computed Tomography after Intravenous Thrombolysis in Acute Anterior Circulation Ischemic Stroke Is Associated with Poor Outcome
Background: Identifying early predictors of functional outcome after acute ischemic stroke (AIS) is important for planning rehabilitation strategies. Internal cerebral veins (ICV) drain deep parts of brain, run parallel to each other, and consistently seen on computed tomography angiography (CTA). Even minor asymmetry in their filling can be identified. We hypothesized that venous drainage would be impaired in patients with acute occlusion of internal carotid artery or middle cerebral artery. Because systemic thrombolysis can alter the vascular findings, we evaluated the relationship between ICV asymmetry on follow-up CTA ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Vijay K. Sharma, Leonard L.L. Yeo, Hock L. Teoh, Liang Shen, Bernard P.L. Chan, Raymond C. Seet, Aftab Ahmad, Vincent F. Chong, Prakash R. Paliwal Tags: Original Articles Source Type: research