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Thalamic perforating artery stroke on computed tomography perfusion in a patient with coronavirus disease 2019
We present a case illustrating the value of CT perfusion to identify acute small subcortical infarcts in a patient with COVID-19 admitted to an intensive care unit for bilateral pneumonia and pulmonary embolism presenting with sudden right limb weakness.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2020 Category: Neurology Authors: Salvatore Rudilosso, Diana Esteller, Xabier Urra, Ángel Chamorro Tags: Case Report Source Type: research

Reversible Cerebral Vasoconstriction Syndrome and Dissection in the Setting of COVID-19 Infection
The current COVID-19 pandemic has recently brought to attention the myriad of neuro- logic sequelae associated with Coronavirus infection including the predilection for stroke, particularly in young patients. Reversible cerebral vasoconstriction syndrome (RCVS) is a well-described clinical syndrome leading to vasoconstriction in the intracra- nial vessels, and has been associated with convexity subarachnoid hemorrhage and oc- casionally cervical artery dissection. It is usually reported in the context of a trigger such as medications, recreational drugs, or the postpartum state; however, it has not been described in COVID-19 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2020 Category: Neurology Authors: Katarina Dakay, Gurmeen Kaur, Edwin Gulko, Justin Santarelli, Christian Bowers, Stephan A Mayer, Chirag D Gandhi, Fawaz Al-Mufti Tags: Case Report Source Type: research

“COVID-19 and cervical artery dissection- A causative association?”
COVID-19 is a pandemic disease which predominantly affects the respiratory system, however it also causes multi-organ dysfunction in a subset of patients. There is a growing evidence that it increases the propensity of strokes in younger patients. Besides producing a prothrombotic state, arterial dissection could be one of its many manifestations, increasing the risks of stroke. Herein, we report the first case of spontaneous bilateral vertebral artery dissection in a patient with COVID-19. 39-year female presented with spontaneous bilateral vertebral artery dissections without any instigating traumatic events and no histo...
Source: Journal of Stroke and Cerebrovascular Diseases - June 12, 2020 Category: Neurology Authors: Pratit Patel, Priyank Khandelwal, Gaurav Gupta, Amit Singla Source Type: research

Acute Stroke Care Algorithm in a Private Tertiary Hospital in the Philippines During the COVID-19 Pandemic: A Third World Country Experience
Since March 2020, we have experienced an influx of COVID-19 positive patients. As of April 27, 2020 the COVID-19 pandemic has claimed the lives of at least 27 healthcare professionals while infecting 1080 healthcare professionals in the Philippines.1 Despite attempts to formalize protocols and treatment pathways to ensure the safety of healthcare professionals while optimizing patient care, Philippine healthcare workers from every department still continue to suffer from COVID-19 infections. These affect not only acute care but also emergency response systems such as the brain attack code.
Source: Journal of Stroke and Cerebrovascular Diseases - June 19, 2020 Category: Neurology Authors: Christian Oliver C. Co, Jeryl Ritzi T. Yu, Cristina Macrohon-Valdez, Lina C. Laxamana, Vincent Paul E. De Guzman, Remy Margarette M. Berroya-Moreno, Manuel M. Mariano, Peter Paul Dela Paz Rivera, Joana Lyn M. Racpan-Cauntay, Karen Czarina S. Ilano, Evita Tags: Original Article Source Type: research

COVID-19 Impact on Stroke Presentations
As Covid-19 evolved into a world-wide pandemic, hospitals reported marked declines in strokes, only to be followed by reports of increased numbers of young people presenting with large-vessel occlusions. We reviewed our patient data-base to determine if similar or other novel trends were present.
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2020 Category: Neurology Authors: Sheryl Strasser, Laszlo Miskolczi, John Cunha, Lori Justynski Source Type: research

Posterior Reversible Encephalopathy Syndrome in Patients with Coronavirus Disease 2019: Two Cases and a Review of the Literature
Central nervous system (CNS) manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection include encephalopathy, encephalitis, meningitis, acute disseminated encephalomyelitis, and stroke [1], both as a result of direct viral invasion of the central nervous system [2 –5] and as a consequence of critical illness and systemic infection [6]. Coronavirus disease 2019 (COVID-19) may also cause significant changes in endothelial morphology, including disruption of intercellular junctions, cell swelling, and a loss of contact with the basal membrane [7].
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2020 Category: Neurology Authors: Pria Anand, K. H.Vincent Lau, David Y Chung, Deepti Virmani, Anna M. Cervantes-Arslanian, Asim Mian, Courtney E. Takahashi Source Type: research

Large vessel occlusion secondary to COVID-19 hypercoagulability in a young patient: A Case Report and Literature Review
We report a case of 33-year-old African American woman with COVID-19 who developed acute malignant middle cerebral artery infarction due to thromboembolic occlusion of the left terminal internal carotid artery and middle cerebral artery stem. Mechanical thrombectomy was challenging and ultimately unsuccessful resulting in limited reperfusion of
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2020 Category: Neurology Authors: Thomas John Pisano, Ian Hakkinen, Igor Rybinnik Source Type: research

Transcranial Doppler Ultrasound Evidence of Active Cerebral Embolization in COVID-19
: To report six consecutive patients with confirmed coronavirus disease-2019 (COVID-19) who underwent Transcranial Doppler (TCD) ultrasonography evaluation for cerebral microemboli in the setting of suspected or confirmed acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - December 9, 2020 Category: Neurology Authors: Ayush Batra, Jeffrey R. Clark, Katie LaHaye, Nathan A. Shlobin, Steven C. Hoffman, Zachary S. Orban, Katharine Colton, Jane E. Dematte, Farzaneh A. Sorond, Igor J. Koralnik, Eric M. Liotta Source Type: research

Coronavirus Positive Patients Presenting with Stroke-Like Symptoms
Several studies from Wuhan, China have reported neurological manifestations in patients who tested positive for coronavirus disease 2019 (COVID-19). One study reported 214 COVID-19 positive patients, out of which 41.1% had severe infection. 5.7% of patients with severe infection had acute cerebrovascular disease1. Another study looked at 221 COVID-19 positive patients, out of which 5% had ischemic infarcts and 0.5% had cerebral hemorrhage2. A recent study from Mount Sinai Hospital in New York reported five cases of cerebral infarcts due to large vessel occlusion in patients who tested positive for COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2021 Category: Neurology Authors: Shaista Alam, Robin N. Dharia, Elan Miller, Fred Rincon, Diana L. Tzeng, Rodney D. Bell Source Type: research

Cerebral Venous Sinus Thrombosis in COVID-19 Patients: A Multicenter Study and Review of Literature
COVID-19 infection has been known to predispose patients to both arterial and venous thromboembolic events such as deep venous thrombosis, pulmonary embolism, myocardial infarction, and stroke. A few reports from the literature suggest that Cerebral Venous Sinus Thrombosis (CVSTs) may be a direct complication of COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - March 4, 2021 Category: Neurology Authors: Mohamad Abdalkader, Shamsh P. Shaikh, James E. Siegler, Anna M. Cervantes-Arslanian, Cristina Tiu, Razvan Alexandru Radu, Vlad Eugen Tiu, Dinesh V. Jillella, Ossama Yassin Mansour, V íctor Vera, Ángel Chamorro, Jordi Blasco, Antonio López, Mudassir Far Source Type: research

Response to letter to the editor,
We would like to thank Dr Nzwalo and Dr Logallo for their interest in our paper about the impact of the lockdown measures, enforced in March 2020 to control the spread of Covid-19 outbreak, on stroke admissions and treatments in Campania, the third most-populous and the most-densely populated region in Italy.
Source: Journal of Stroke and Cerebrovascular Diseases - March 10, 2021 Category: Neurology Authors: Paolo Candelaresi Tags: Letter to the Editor Source Type: research

Response to the Letter to the Editor: Consideration Needed for Early Anticoagulation Following Intravenous tPA in Patients with COVID-19
We thank Dr. Angelo Jimenez and his colleagues for their letter to the editor regarding our report of a multicenter series of patients with coronavirus disease 2019 (COVID-19) who received intravenous (IV) tissue plasminogen activator (tPA) for suspected acute ischemic stroke. Their letter emphasizes the important contribution of a hypercoagulable state in patients with COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2021 Category: Neurology Authors: Thiago Carneiro, Jonathan Dashkoff, Lester Leung, Christa O'Hana S. Nobleza, Erika Marulanda-Londono, Mausaminben Hathidara, Sebastian Koch, Nicole Sur, Alexandra Boske, Barbara Voetsch, Ali Daneshmand, Julie Shulman, Giaocchino Curiale, David M. Greer, J Source Type: research

Response to Letter to the Editor
This is in response to the question asked by the author of the manuscript entitled “Comments on Coronavirus Positive Patients Presenting with Stroke-Like Symptoms”.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2021 Category: Neurology Authors: Shaista Alam Source Type: research

Racial Disparities in Ischemic Stroke among Patients with COVID-19 in the United States
Cerebrovascular prevalence is high in patients with coronavirus disease 2019 (COVID-19). However, whether racial disparities exist among this population have not been systematically explored.
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2021 Category: Neurology Authors: Alain Lekoubou, Matt Pelton, Djibril M. Ba, Addy Ssentongo Source Type: research

Response to Letter to the Editor
We would like to thank Dr Nzwalo and Dr Logallo for their interest in our paper about the impact of the lockdown measures, enforced in March 2020 to control the spread of Covid-19 outbreak, on stroke admissions and treatments in Campania, the third most-populous and the most-densely populated region in Italy.
Source: Journal of Stroke and Cerebrovascular Diseases - March 10, 2021 Category: Neurology Authors: Paolo Candelaresi Tags: Letter to the Editor Source Type: research

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