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Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-analysis of Incidence, Outcomes and Predictors
COVID-19 is a multi-system infection which predominantly affects the respiratory system, but also causes systemic inflammation, endothelialitis and thrombosis. The consequences of this include renal dysfunction, hepatitis and stroke. In this systematic review, we aimed to evaluate the epidemiology, clinical course, and outcomes of patients who suffer from stroke as a complication of COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - December 15, 2020 Category: Neurology Authors: Isabel Siow, Keng Siang Lee, John J.Y. Zhang, Seyed Ehsan Saffari, Adeline Ng, Barnaby Young Source Type: research

Bilateral large vessel occlusion causing massive ischemic stroke in a covid-19 patient
The case of a 70-year-old male presenting an ischemic stroke related to COVID-19 infection is described. He was initially admitted to the hospital with respiratory insufficiency syndrome secondary to pneumonia caused by SARS Co2. In the next days, he developed rapid neurological deterioration characterized by drowsiness which progressed to deep coma. D-dimer was elevated. Brain CT scan showed bilateral massive ischemic stroke located in the anterior circulation, CT angiogram showed occlusion in the left internal carotid artery and the right middle cerebral artery.
Source: Journal of Stroke and Cerebrovascular Diseases - January 7, 2021 Category: Neurology Authors: Luis A. Robles Tags: Case Report Source Type: research

International survey of Mechanical Thrombectomy Stroke systems of care during COVID-19 pandemic
The COVID-19 pandemic has strained the healthcare systems across the world but its impact on acute stroke care is just being elucidated. We hypothesized a major global impact of COVID-19 not only on stroke volumes but also on various aspects of thrombectomy systems.
Source: Journal of Stroke and Cerebrovascular Diseases - April 6, 2021 Category: Neurology Authors: Dileep R Yavagal, Vasu Saini, Violiza Inoa, Hannah E Gardener, Sheila O Martins, Manav Fakey, Santiago Ortega, Ossama Mansour, Thomas Leung, Ashutosh P Jadhav, Jennifer Potter-Vig, Anurag Mairal, Miao Zhongrong, P.N. Sylaja, Andrew M Demchuk, MT2020 Globa Source Type: research

Outcomes of COVID-19 complications and their possibilities as potential triggers of stroke
The coronavirus disease 2019 (COVID-19) has been a pandemic like no other seen in our times. It has impacted the entire globe affecting more than 180 countries with 81.9 million cases and 1.7 million deaths as of December 29, 20201. Unlike other virus-related spread, COVID-19 since its early days is known to have a high infection rate as well as high mortality, which in turn has resulted in such a devastating impact across the world. The mortality rates among hospitalized patients with COVID-19 infection without stroke range from 22% to 45%2,3, but the mortality was very high (38%) in stroke patients with COVID-19 infections4.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2021 Category: Neurology Authors: Urvish Patel, Preeti Malik, Deep Mehta, Priyanka Rajput, Mashu Shrivastava, Madiha Naveed, Eseosa Urhoghide, Mehwish Martin, Shamima Somi, Richa Jaiswal, Achint Patel, Avantika Israni, Jagmeet Singh, Asim Kichloo, Shamik Shah, Abhishek Lunagariya Source Type: research

Decline in rehab transfers among rehab-eligible stroke patients during the COVID-19 pandemic
: To characterize differences in disposition arrangement among rehab-eligible stroke patients at a Comprehensive Stroke Center before and during the COVID-19 pandemic.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2021 Category: Neurology Authors: Lauren Thau, Taylor Siegal, Mark E. Heslin, Ameena Rana, Siyuan Yu, Scott Kamen, Austin Chen, Nicholas Vigilante, Sheri Gallagher, Kevin Wegner, Jesse M. Thon, Ryna Then, Pratit Patel, Terri Yeager, Tudor G. Jovin, Rohini J. Kumar, David E. Owens, James E Source Type: research

Exploring the relationship between Air Quality and Ischemic Stroke Admissions during the COVID-19 pandemic
Amongst all the global catastrophe due to Coronavirus disease 2019, a significant bright spot is a reduction in air pollution as countries undergo lockdowns to limit the spread of infection. Another reduction that has been reported is in the number of strokes presenting to hospitals, despite the virus implicated in causing a hypercoagulable state. Acute exposure to air pollution has been linked to increase in stroke incidence and the improvement in air quality may be responsible for the decrease in stroke presentations.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2021 Category: Neurology Authors: Sajid Hameed, Maria Khan, Zafar Fatmi, Mohammad Wasay Source Type: research

Comments on Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-Analysis of Incidence, Outcomes and Predictors
We read with interest the research article entitled “Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-Analysis of Incidence, Outcomes and Predictors”,1 it was a systematic review and meta-analysis on stroke incidence and different outcomes over COVID-19 patients. We are particularly concerned about the potential gro ups of overlapped COVID-19 stroke subjects in the meta-analysis under the worldwide SARS-CoV-2 pandemic.
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2021 Category: Neurology Authors: Sunny Chi Lik Au Tags: Letter to the Editor Source Type: research

COVID-19 encephalitis with SARS-CoV-2 detected in cerebrospinal fluid presenting as a stroke mimic
We report the case of a 35-year-old male with COVID-19 encephalitis presenting as a stroke mimic with sudden-onset expressive and receptive dysphasia, mild confusion and right arm incoordination. The patient received thrombolysis for a suspected ischaemic stroke, but later became febrile and SARS-CoV-2 was detected in cerebrospinal fluid. Electroencephalography demonstrated excess in slow waves, but neuroimaging was reported as normal. Respiratory symptoms were absent throughout and nasopharyngeal swab was negative for SARS-CoV-2.
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2021 Category: Neurology Authors: Diarmuid Glavin, Denise Kelly, Greta Karen Wood, Beth MS McCausland, Mark Alexander Ellul, Aravinthan Varatharaj, Ian Galea, Rhys Huw Thomas, Benedict Daniel Michael, Brian Gallen, CoroNerve Study Management Group Tags: Case Report Source Type: research

Stroke mechanism in COVID-19 infection: A prospective case-control study
The characteristics and pathophysiological mechanisms involved in acute ischemic stroke in patients with COVID-19 infection have not been fully clarified. We prospectively studied the phenotypic and etiological features of acute stroke occurring in COVID-19 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - May 31, 2021 Category: Neurology Authors: Mehmet Akif Topcuoglu, Mehmet Yasir Pektezel, Dogan Din ç Oge, Nihal Deniz Bulut Yüksel, Cansu Ayvacioglu, Ezgi Demirel, Sinan Balci, Anil Arat, Seda Banu Akinci, Ethem Murat Arsava Source Type: research

Impact of COVID-19 pandemic on stroke severity and mortality in the south-east of Santiago, Chile
Background and purpose: Chile has been one of the most affected countries by the COVID-19 pandemic, with one of the highest case rates per population. This has affected the epidemiological behaviour of various pathologies. We analyze the impact of the pandemic on the number of admissions due to stroke, its severity and mortality in Santiago, Chile.Methods: a multicenter observational study based on the records of the 3 hospitals of the South East health service in Santiago, Chile. We recorded the number of patients admitted for ischemic stroke between 01 January 2020 and 30 June 2020.
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2021 Category: Neurology Authors: Andres Silva-Pozo, Jose Vallejos, Juan Almeida, Mariano Martoni, Reinaldo Uribe-San Martin, Mar ía Miranda, Pablo Diaz, Dominga García, Victor Navía Source Type: research

Utilization and Outcomes of Acute Revascularization Treatment in Ischemic Stroke Patients with SARS-CoV-2 Infection
Our understanding of outcomes in acute ischemic stroke patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection following acute revascularization treatments (as intravenous thrombolysis and/or thrombectomy) is based on small case series.1-3. An international panel4 cautioned regarding the potential for high rate of death or disability and post thrombolytic intracerebral hemorrhage (ICH)s in acute ischemic stroke patients with SARS-CoV-2 infection due to elevated concentrations of inflammation and hypercoagulability markers such as leukocytosis, and C reactive protein and D dimers and multisystem dysfunction.
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2021 Category: Neurology Authors: Adnan I. Qureshi, William I. Baskett, Wei Huang, Muhammad F. Ishfaq, S. Hasan Naqvi, Brandi R. French, Farhan Siddiq, Camilo R. Gomez, Chi-Ren Shyu Tags: SARS-CoV-2 and acute revascularization Source Type: research

Utilization and Outcomes of Acute Revascularization Treatments in Ischemic Stroke Patients with SARS-CoV-2 Infection
Our understanding of outcomes in acute ischemic stroke patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection following acute revascularization treatments (as intravenous thrombolysis and/or thrombectomy) is based on small case series.1 –3 An international panel4 cautioned regarding the potential for high rate of death or disability and post thrombolytic intracerebral hemorrhage (ICH)s in acute ischemic stroke patients with SARS-CoV-2 infection due to elevated concentrations of inflammation and hypercoagulability markers such as leukocytosis, and C reactive protein and D dimers and multisystem dysfunction.
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2021 Category: Neurology Authors: Adnan I. Qureshi, William I. Baskett, Wei Huang, Muhammad F. Ishfaq, S. Hasan Naqvi, Brandi R. French, Farhan Siddiq, Camilo R. Gomez, Chi-Ren Shyu Source Type: research

Cryptogenic, Embolic Stroke —Looking Backstage
Stroke is a common and devastating event and the majority of cases are caused by thromboembolism from the left atrium, left ventricle or left sided valves. This case report describes a case of embolic stroke with the origin of the thrombus from the left inferior pulmonary vein. The importance of this case is twofold. Firstly, it is the fourth case report of pulmonary venous thrombosis, a very rare condition, due to COVID-19 infection and secondly, it focuses attention on the fact that the left atrium is not the most proximal address of arterial thromboembolism —the pulmonary veins are.
Source: Journal of Stroke and Cerebrovascular Diseases - March 2, 2022 Category: Neurology Authors: Prof James Ker Tags: Case Report Source Type: research

Maintained acute stroke admission during the first wave COVID-19 pandemic in Sweden, a register-based study
Clinicians and researchers have addressed concerns about the negative impact of COVID-19 outbreaks on the ability of health care systems to provide timely assessment and acute therapies to patients with stroke. The aim of this study is to describe stroke care during the first wave of the COVID-19 pandemic compared to the same period the year before at an acute care hospital in Sweden.
Source: Journal of Stroke and Cerebrovascular Diseases - July 26, 2022 Category: Neurology Authors: Melissa Rydell, Per Wester, Ann-Charlotte Laska, Ann-Sofie Rudberg Source Type: research

Recombinant tissue plasminogen activator (rTPA) management for first onset acute Ischemic Stroke with covid -19 and non-covid -19 patients
In this study we compare the efficacy and safety of Tissue plasminogen activator (rTPA) in acute ischemic stroke (AIS) patients with or without Covid-19 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2023 Category: Neurology Authors: Eman M Khedr, Ahmed Abdelwarith, Gehad M Moussa, Mostafa Saber Source Type: research

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