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Nonalcoholic Fatty Liver Disease in Patients with Acute Ischemic Stroke is associated with more severe stroke and worse outcome.
There is a paucity of data regarding the association between non alcoholic fatty liver disease (NAFLD) and acute ischemic stroke. Stroke is largely preventable, so that knowledge of risk factors is essential to achieve reductions in the stroke rate and resulting disease burden.
Source: Journal of Clinical Lipidology - May 10, 2017 Category: Lipidology Authors: Sabry M. Abdeldyem, Tarek Goda, Samy A. Khodeir, Sabry Abou saif, Sherief Abd-Elsalam Source Type: research

Admission LDL-cholesterol, statin pretreatment and early outcomes in acute ischemic stroke
Elevated LDL-cholesterol (LDL-C) levels increase the risk of stroke and vascular events. Initiation and maintenance of lipid-lowering therapy after acute ischemic stroke (AIS) appears to be guided by LDL-C levels.1 The EUROASPIRE III stroke-specific module shows that secondary prevention and risk factor control in patients after ischemic stroke need to be improved since about half of patients are not achieving target lipid levels defined in European guidelines.2 However, lower levels of LDL-C are paradoxically associated with increased mortality in ST elevation myocardial infarction patients.
Source: Journal of Clinical Lipidology - August 7, 2023 Category: Lipidology Authors: Joon-Tae Kim, Ji Sung Lee, Beom Joon Kim, Jihoon Kang, Keon-Joo Lee, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Tai Hwan Park, Kyungbok Lee, Jun Lee, Keun-Sik Hong, Yong-Jin Cho, Hong-Kyun Park, Byung-Chul Lee, Kyung Tags: Original Research Source Type: research

Primary Prevention of Stroke is Strongly Correlated with Low-Density-Lipoprotein Cholesterol Reduction: A Meta-Regression Analysis
Statins have become the cornerstone of therapy for both primary and secondary prevention of cardiovascular (CV) and cerebrovascular diseases (CVD). Numerous studies and meta-analyses have documented these benefits independent of low-density-lipoprotein cholesterol (LDL-C) lowering. There are discrepant reports regarding the dependence of the stroke benefits on the baseline LDL-C levels. The relevance of LDL-C reduction from baseline in the era of pleiotropic benefits needs further exploration, especially, while comparing the primary stroke cohort with the secondary stroke prevention cohort.
Source: Journal of Clinical Lipidology - July 1, 2023 Category: Lipidology Authors: Samit Ghosal, Krishna G Seshadri Tags: Lipid Management in Special Populations Source Type: research

Low LDL-C and risk of hemorrhagic stroke in Chinese adults
It is well-established that higher LDL and total cholesterol are associated with increased risk of atherosclerotic cardiovascular disease (ASCVD), that is, coronary heart disease (CHD) and ischemic stroke events, and that cholesterol-lowering by statins and other therapies reduce ASCVD risk. However, the picture is less clear for the 10% to 20% of strokes that are hemorrhagic rather than ischemic. A meta-analysis of observational studies shows that lower levels of LDL-C and total cholesterol are associated with higher risk of hemorrhagic strokes (HS), and with intracranial hemorrhage (ICH), a subset of HS.
Source: Journal of Clinical Lipidology - September 1, 2018 Category: Lipidology Authors: Rachel H. Mackey Tags: Editorial Source Type: research

Improvement in Cognitive Function and Reducing the Risk of Developing Cardiovascular Events/ Stroke in Homocysteinemia
A patient presenting with recurrent stroke and angina was diagnosed with homocysteinemia. Elevated homocysteine levels increase the risk of atherosclerosis and venous thrombosis, which can lead to strokes, and cardiovascular events, while significantly impacting an individual's brain function, including the onset of depression/psychosis.
Source: Journal of Clinical Lipidology - July 1, 2023 Category: Lipidology Authors: Kirollos Gabrah, Mirra Srinivasan, Hadia Arzoun, Siji Thomas, Barry Tedder Tags: Genetic Disorders Source Type: research

Impact of Obesity and Healthy Eating Index on Coronary Heart Disease, Stroke, and Cardiovascular Disease Mortality in United States Adults*
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Source: Journal of Clinical Lipidology - May 1, 2013 Category: Lipidology Authors: Rohini J. Patel, Geeta Sikand, Christopher Patao, Nathan Wong Tags: Abstracts Source Type: research

Lipid Abnormalities in Foreign and US-Born Patients in a Medical Group
This study was funded by the HealthPartners Research Foundation (a partnership grant to TEK); The Heart Disease and Stroke Prevention Unit at the Minnesota Department of Health from a Capacity Building - Cooperative Agreement grant from the Centers for Disease Control and Prevention CDC) 5U50DP000721-04; and NIH training grant T32 HL69764 (supporting CJB).
Source: Journal of Clinical Lipidology - May 1, 2013 Category: Lipidology Authors: Jawali Jaranilla, Teri Defor, Gabriella Vasquez Benitez, Thomas Kottke Tags: Abstracts Source Type: research

From the Editor: What is obesity?
The concern about the prevalence of obesity in the population of the United States (now around the world) has grown as our epidemiologic colleagues have pointed out the associated disease states such as dyslipidemia, high blood pressure, diabetes, myocardial infarction, and stroke. We now recognize it to be a disease entity unto itself with causative elements in both genetic and environmental realms. There seems to be general agreement that this disease is linked to an increase in adipose tissue generally but with issues of enhanced effect when the excess fat cells are located within the abdominal cavity or when there is a...
Source: Journal of Clinical Lipidology - June 5, 2013 Category: Lipidology Authors: W. Virgil Brown Tags: Foreword Source Type: research

Comparison of Lipid Profiles and BMI by Age Groups in Acute Ischemic Stroke*
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Source: Journal of Clinical Lipidology - May 1, 2014 Category: Lipidology Authors: Demetrios Doukas, Mauro Montevecchi, Michael Schneck, John Barron, Binh An Phan Tags: Abstracts Source Type: research

Real-World Costs for First and Recurrent Events of Myocardial Infarction and Stroke in the Elderly Medicare Population
Dr. Becker has received a grant from Amgen Inc.
Source: Journal of Clinical Lipidology - May 1, 2015 Category: Lipidology Authors: David Becker, Pradeep Sharma, Meredith Kilgore, Nicole Yurgin Source Type: research

Ischemic Stroke in a Young Adult with Extremely Elevated Lipoprotein(a): a Case Report and Review of Literature
Source: Journal of Clinical Lipidology - July 8, 2016 Category: Lipidology Authors: Dharshan Lakshminarayan, Tarec K. Elajami, Suresh Devabhaktuni, Francine K. Welty Source Type: research

Intensive Lifestyle Interventions Decrease Stroke Risk Factors In 18 Days In Patients With Carotid Stenosis
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Source: Journal of Clinical Lipidology - May 1, 2017 Category: Lipidology Authors: Francisco Ramirez, Neil Nedley Source Type: research

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