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Is the contralesional hemisphere a suitable target for noninvasive brain stimulation after stroke?
Stroke is the leading cause of adult disability and there are no treatments that can repair neural damage that results from stroke. Functional recovery for many patients is modest and therefore adjuvants to traditional therapies are urgently required. This talk will revisit the use of non-invasive brain stimulation (NIBS) as a potential adjuvant for stroke rehabilitation, which is well documented in clinical neurophysiological research, but not routinely used in clinical practice. One tenet is that functional restoration may be enhanced using techniques that increase excitability in the hemisphere in which the lesion has o...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 29, 2015 Category: Neurology Authors: Winston D. Byblow, Cathy M. Stinear Source Type: research

Proportional upper limb recovery after stroke is predicated upon corticospinal tract integrity
For most patients after stroke, upper limb impairment resolves by approximately 70% of the maximum amount possible i.e., the proportional recovery rule (PRR; Prabhakaran et al., Neurorehabil Neural Repair 2008 22: 64-71). This presentation will demonstrate how the PRR relies on corticospinal system integrity as determined with transcranial magnetic stimulation and diffusion-weighted MRI. Data were obtained from 48 patients previously enrolled in an upper limb rehabilitation interventional trial.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 29, 2015 Category: Neurology Authors: Winston D. Byblow, Cathy M. Stinear Source Type: research