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Source: Neurochemical Research
Therapy: Vagus Nerve Stimulation Therapy
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Total 1 results found since Jan 2013.
L-PGDS Mediates Vagus Nerve Stimulation-Induced Neuroprotection in a Rat Model of Ischemic Stroke by Suppressing the Apoptotic Response.
This study investigated the role of L-PGDS in cerebral I/R and whether this process was involved in the mechanism of VNS-mediated neuroprotection. Male Sprague-Dawley rats were pretreated with a lentiviral vector (LV) through intracerebroventricular injection, followed by middle cerebral artery occlusion (MCAO) and VNS treatment. The expression of L-PGDS in the peri-infarct cortex was examined. The localization of L-PGDS was determined using double immunofluorescence staining. Neurologic scores, infarct volume and neuronal apoptosis were evaluated at 24 h after reperfusion. The expression of apoptosis-related molecules wa...
Source: Neurochemical Research - November 28, 2016 Category: Neuroscience Authors: Zhang L, Ma J, Jin X, Jia G, Jiang Y, Li C Tags: Neurochem Res Source Type: research
