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Specialty: Child Development
Source: Developmental Medicine and Child Neurology
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Total 57 results found since Jan 2013.
Are children with acute arterial ischaemic stroke eligible for hyperacute thrombolysis? A retrospective audit from a tertiary UK centre
AimThe aim of this study was to evaluate the number of children with acute arterial ischaemic stroke (AIS) who would have been eligible for hyperacute thrombolysis in the authors' unit (Great Ormond Street Hospital, London, UK) and to identify barriers to this treatment.
MethodWe compared the characteristics of children with a diagnosis of acute AIS, identified from neuroimaging databases, seen at our centre between January 2006 and December 2011. The criteria for hyperacute thrombolysis were predefined by us: age ≥8y; imaging‐confirmed diagnosis of acute AIS and arrival at our centre within 6 hours of symptom onset; ...
Source: Developmental Medicine and Child Neurology - September 18, 2014 Category: Child Development Authors: Clara Marecos, Roxana Gunny, Robert Robinson, Vijeya Ganesan Tags: Original Article Source Type: research
Association of transcallosal motor fibres with function of both hands after unilateral neonatal arterial ischemic stroke
The objective of this study was to investigate the involvement of the motor fibres of the corpus callosum after unilateral neonatal arterial ischemic stroke (NAIS) of the middle cerebral artery territory and the relationship to both ipsilesional and contralesional hand function.
MethodUsing high‐resolution structural magnetic resonance imaging (MRI), functional MRI, and magnetic resonance diffusion‐tractography, we compared the midsagittal area of the motor part of the corpus callosum (defined by the fibres connecting the precentral gyri) between 33 7‐year‐old children after unilateral NAIS and 31 typically develop...
Source: Developmental Medicine and Child Neurology - August 1, 2017 Category: Child Development Authors: Samuel Groeschel, Lucie Hertz ‐Pannier, Matthieu Delion, Sébastien Loustau, Béatrice Husson, Manoelle Kossorotoff, Cyrille Renaud, Sylvie Nguyen The Tich, Stéphane Chabrier, Mickael Dinomais, Tags: Original Article Source Type: research
A common data language for clinical research studies: the National Institute of Neurological Disorders and Stroke and American Academy for Cerebral Palsy and Developmental Medicine Cerebral Palsy Common Data Elements Version 1.0 recommendations
To increase the efficiency and effectiveness of clinical research studies, cerebral palsy (CP) specific Common Data Elements (CDEs) were developed through a partnership between the National Institute of Neurological Disorders and Stroke (NINDS) and the American Academy of Cerebral Palsy and Developmental Medicine (AACPDM). International experts reviewed existing NINDS CDEs and tools used in studies of children and young people with CP. CDEs were compiled, subjected to internal review, and posted online for external public comment in September 2016. Guided by the International Classification of Functioning, Disability and H...
Source: Developmental Medicine and Child Neurology - March 1, 2018 Category: Child Development Authors: Ver ónica Schiariti, Eileen Fowler, Joline E Brandenburg, Eric Levey, Sarah Mcintyre, Theresa Sukal‐Moulton, Sharon L Ramey, Jessica Rose, Susan Sienko, Elaine Stashinko, Laura Vogtle, Robin S Feldman, James I Koenig Tags: Review Source Type: research
Basilar artery strokes in children: good outcomes with conservative medical treatment
AimTo describe outcomes and outcome predictors in childhood basilar artery stroke (BAS).
MethodWe prospectively enrolled children with BAS with or without basilar artery occlusion (BAO) in the Toronto Children's Stroke Registry from 1992 to 2009. We assessed presenting features and outcomes including Pediatric Stroke Outcome Measure scores.
ResultsAmong 578 children with acute arterial ischemic stroke, 27 had BAS (4.6% including neonates, 6% excluding neonates). Twenty‐four (14 males, 10 females) children met study criteria (mean age at stroke was 8y 10mo; range 0–17y). Eleven children had BAO. Aspirin or anticoagulati...
Source: Developmental Medicine and Child Neurology - February 17, 2013 Category: Child Development Authors: Ana Marissa Lagman‐Bartolome, Ann‐Marie Pontigon, Mahendranath Moharir, Daune L. Macgregor, Rand Askalan, Ivanna Yau, Gabrielle Deveber Tags: Original Article Source Type: research
Cognitive functioning over 2 years after intracerebral hemorrhage in school ‐aged children
This study examined cognitive outcomes after spontaneous ICH in school‐aged children with serial assessments over 2 years after stroke.
MethodSeven children (age range 6–16y, median 13; six males, one female; 57% white, 43% black) presenting with spontaneous ICH (six arteriovenous malformations) were assessed at 3 months, 12 months, and 24 months after stroke. The Pediatric Stroke Outcome Measure (PSOM) quantified neurological outcome and Wechsler Intelligence Scales measured cognitive outcomes: verbal comprehension, perceptual reasoning, working memory, and processing speed.
ResultsPSOM scales showed improved neurolog...
Source: Developmental Medicine and Child Neurology - September 6, 2017 Category: Child Development Authors: Lexa K Murphy, Bruce E Compas, Melissa C Gindville, Kristen L Reeslund, Lori C Jordan Tags: Original Article Source Type: research
Predictive validity of developmental screening in young children with sickle cell disease: a longitudinal follow ‐up study
AimTo assess the predictive validity of developmental screenings in children with sickle cell disease (SCD) for academic outcomes and stroke risk.
MethodParent questionnaires and medical record data were collected for a cohort receiving developmental screenings between September 2004 and May 2008 as toddlers or early school age. Screening outcomes were dichotomized (positive, negative) by a priori criteria. Questionnaires assessed school and social functioning, services received, and quality of life. Medical record data assessed general SCD morbidity and stroke risk.
ResultsForty‐one toddlers (mean age 2y 5mo; 25 males, ...
Source: Developmental Medicine and Child Neurology - February 28, 2018 Category: Child Development Authors: Jeffrey Schatz, Alyssa M Schlenz, Kelsey E Smith, Carla W Roberts Tags: Original Article Source Type: research
Should paediatric stroke be treated as adult stroke?
This commentary is on the original article by Lagman‐Bartolome et al
Source: Developmental Medicine and Child Neurology - February 11, 2013 Category: Child Development Authors: Manoëlle Kossorotoff Tags: Commentary Source Type: research
Determination of interventions for upper extremity tactile impairment in children with cerebral palsy: a systematic review
This study reviewed interventions suitable for treating tactile dysfunction in children with cerebral palsy (CP).
MethodA systematic review was conducted of six databases, searched for population: (‘brain injury’ OR ‘cerebral palsy’ OR ‘stroke’ OR ‘cerebrovascular accident’) and intervention: (‘tactile’ OR ‘sensation’). Inclusion criteria were: (1) published after 1950 in English; (2) participants older than 4 years with brain injury; (3) upper limb intervention; and (4) examined tactile registration or perception.
ResultsOf 2938 studies identified, 30 met the inclusion criteria. Results from inclu...
Source: Developmental Medicine and Child Neurology - March 26, 2014 Category: Child Development Authors: Megan L Auld, Remo Russo, G Lorimer Moseley, Leanne M Johnston Tags: Review Source Type: research
Thrombolytics for acute stroke in children: eligibility, practice variability, and pediatric stroke centers
This commentary is on the original article by Marecos et al.
Source: Developmental Medicine and Child Neurology - October 13, 2014 Category: Child Development Authors: Lori C Jordan Tags: Commentary Source Type: research
A practical approach to acute hemiparesis in children
Acute hemiparesis in children is a common clinical syndrome presenting to a variety of care settings. The recognition and the differential diagnosis is challenging, particularly in young children. Arterial ischaemic stroke (AIS) is the primary diagnosis to be considered as this requires emergency investigations and management; however, there are several conditions collectively described as ‘stroke mimics’ that need consideration. Accurate diagnosis is essential for appropriate management. Clinical data combined with neuroimaging are important for accurate diagnosis and management. This review and the accompanying illus...
Source: Developmental Medicine and Child Neurology - April 1, 2015 Category: Child Development Authors: Sanjay Bhate, Vijeya Ganesan Tags: Invited Review Source Type: research
Reproducibility of two functional field exercise tests for children with cerebral palsy who self‐propel a manual wheelchair
AimThe aim of this study was to examine the test–retest reproducibility (reliability and agreement) of the 6‐minute push test (6MPT) and the one‐stroke push test (1SPT), and construct validity of the 6MPT in children with cerebral palsy (CP) who self‐propel a manual wheelchair.
MethodSeventy‐three children and adolescents with spastic CP (51 males, 22 females; mean age 11y 9mo, SD 3y 7mo, range 4–18y; three unilateral, 70 bilateral) using a manual wheelchair for at least part of the day were recruited from and tested in different rehabilitation settings in the Netherlands and Brazil. Participants were classifie...
Source: Developmental Medicine and Child Neurology - December 18, 2012 Category: Child Development Authors: Olaf Verschuren, Marjolijn Ketelaar, Janke De Groot, FÁbio Vila Nova, Tim Takken Tags: Original Article Source Type: research
How commonly do children with complex cerebral arteriopathy have renovascular disease?
AimTo describe the frequency of renovascular abnormalities and hypertension in an opportunistic cohort of children with complex cerebrovascular disease from a single tertiary/quaternary referral centre.
MethodThis was a retrospective case note and imaging review of children who had had cerebral and renal angiography, with a diagnosis of moyamoya or other occlusive cerebrovascular disease (OCVD). Hypertension was defined as at least three systolic blood pressure readings of the 95th centile or above.
ResultsOf 34 children (12 males, 22 females; median age 5y 11mo, range 2mo‐15y 3mo; 20 with moyamoya, 14 with OCVD), primar...
Source: Developmental Medicine and Child Neurology - December 18, 2012 Category: Child Development Authors: Alex Willsher, Derek J Roebuck, Joanne Ng, Vijeya Ganesan Tags: Original Article Source Type: research
The epidemiology of intermittent and chronic ataxia in children in Manitoba, Canada
AimTo determine the epidemiology of chronic ataxia in children in Manitoba, Canada.
MethodA retrospective study using multiple sources and disease codes identified children (age 0–16y) with chronic ataxia (>2mo duration or recurrent episodes of ataxia) seen at Winnipeg Children's Hospital from 1991 to 2008. Patients with isolated peripheral nerve diseases, vestibular disorders, or brain tumors were excluded.
ResultsWe identified 184 patients (males=females; mean age 15y, SD 7y 8mo) with chronic ataxia. Median age at the presenting symptom onset was 1 year 3 months and at ataxia onset 3 years 1 month. Median durati...
Source: Developmental Medicine and Child Neurology - February 7, 2013 Category: Child Development Authors: Michael S Salman, Esther J Lee, Anindita Tjahjadi, Bernard N Chodirker Tags: Original Article Source Type: research
Neonatal arterial ischemic stroke: it's not just about motor and cognitive outcome
This commentary is on the original article by van der Aa et al.
Source: Developmental Medicine and Child Neurology - January 22, 2013 Category: Child Development Authors: Mahendranath Moharir Tags: Commentary Source Type: research
Predicting developmental plasticity after perinatal stroke
This commentary is on the original article by van der Aa et al.
Source: Developmental Medicine and Child Neurology - May 16, 2013 Category: Child Development Authors: Adam Kirton Tags: Commentary Source Type: research
