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Source: Annual Review of Nutrition
Vaccination: Influenza Vaccine
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Obesity Dysregulates the Immune Response to Influenza Infection and Vaccination Through Metabolic and Inflammatory Mechanisms
Annu Rev Nutr. 2022 Aug 22;42:67-89. doi: 10.1146/annurev-nutr-062320-115937.ABSTRACTThe COVID-19 pandemic demonstrates that obesity alone, independent of comorbidities, is a significant risk factor for severe outcomes from infection. This susceptibility mirrors a similar pattern with influenza infection; that is, obesity is a unique risk factor for increased morbidity and mortality. Therefore, it is critical to understand how obesity contributes to a reduced ability to respond to respiratory viral infections. Herein, we discuss human and animal studies with influenza infection and vaccination that show obesity impairs imm...
Source: Annual Review of Nutrition - August 22, 2022 Category: Nutrition Authors: Saame Raza Shaikh Nancie J MacIver Melinda A Beck Source Type: research
