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Specialty: Biomedical Engineering
Source: Annals of Biomedical Engineering

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Total 84 results found since Jan 2013.

Surgical Robotics for Intracerebral Hemorrhage Treatment: State of the Art and Future Directions
Ann Biomed Eng. 2023 Jul 5. doi: 10.1007/s10439-023-03295-x. Online ahead of print.ABSTRACTIntracerebral hemorrhage (ICH) is a stroke subtype with high mortality and disability, and there are no proven medical treatments that can improve the functional outcome of ICH patients. Robot-assisted neurosurgery is a significant advancement in the development of minimally invasive surgery for ICH. This review encompasses the latest advances and future directions of surgical robots for ICH. First, three robotic systems for neurosurgery applied to ICH are illustrated. Second, the key technologies of robot-assisted surgery for ICH ar...
Source: Annals of Biomedical Engineering - July 5, 2023 Category: Biomedical Engineering Authors: Zhuojin Wu Danyang Chen Chao Pan Ge Zhang Shiling Chen Jian Shi Cai Meng Xingwei Zhao Bo Tao Diansheng Chen Wenjie Liu Han Ding Zhouping Tang Source Type: research

Hip and Knee Joint Kinematics Predict Quadriceps Hyperreflexia in People with Post-stroke Stiff-Knee Gait
In this study, we explore a clinically accessible biomechanical predictor set that can accurately predict rectus femoris (RF) reaction after knee flexion assistance in pre-swing by a powered orthosis. We examined a total of 14 gait parameters based on gait kinematic, kinetic, and simulated muscle-tendon states from 8 post-stroke individuals with Stiff-Knee gait (SKG) wearing a knee exoskeleton robot. We independently performed both parametric and non-parametric variable selection approaches using machine learning regression techniques. Both models revealed the same four kinematic variables relevant to knee and hip joint mo...
Source: Annals of Biomedical Engineering - May 3, 2023 Category: Biomedical Engineering Authors: Jeonghwan Lee Tunc Akbas James Sulzer Source Type: research

Automatic Segmentation of the Left Atrium from Computed Tomography Angiography Images
Ann Biomed Eng. 2023 Mar 8. doi: 10.1007/s10439-023-03170-9. Online ahead of print.ABSTRACTThe left atrial appendage (LAA) causes 91% of thrombi in atrial fibrillation patients, a potential harbinger of stroke. Leveraging computed tomography angiography (CTA) images, radiologists interpret the left atrium (LA) and LAA geometries to stratify stroke risk. Nevertheless, accurate LA segmentation remains a time-consuming task with high inter-observer variability. Binary masks of the LA and their corresponding CTA images were used to train and test a 3D U-Net to automate LA segmentation. One model was trained using the entire un...
Source: Annals of Biomedical Engineering - March 8, 2023 Category: Biomedical Engineering Authors: Amaan Kazi Sage Betko Anish Salvi Prahlad G Menon Source Type: research

Fluid Mechanical Effects of Fetal Aortic Valvuloplasty for Cases of Critical Aortic Stenosis with Evolving Hypoplastic Left Heart Syndrome
Ann Biomed Eng. 2023 Feb 13. doi: 10.1007/s10439-023-03152-x. Online ahead of print.ABSTRACTFetuses with critical aortic stenosis (FAS) are at high risk of progression to HLHS by the time of birth (and are thus termed "evolving HLHS"). An in-utero catheter-based intervention, fetal aortic valvuloplasty (FAV), has shown promise as an intervention strategy to circumvent the progression, but its impact on the heart's biomechanics is not well understood. We performed patient-specific computational fluid dynamic (CFD) simulations based on 4D fetal echocardiography to assess the changes in the fluid mechanical environment in the...
Source: Annals of Biomedical Engineering - February 13, 2023 Category: Biomedical Engineering Authors: Hong Shen Wong Binghuan Li Andreas Tulzer Gerald Tulzer Choon Hwai Yap Source Type: research

Quantitative Assessment of Aortic Hemodynamics for Varying Left Ventricular Assist Device Outflow Graft Angles and Flow Pulsation
Ann Biomed Eng. 2023 Jan 27. doi: 10.1007/s10439-022-03127-4. Online ahead of print.ABSTRACTLeft ventricular assist devices (LVADs) comprise a primary treatment choice for advanced heart failure patients. Treatment with LVAD is commonly associated with complications like stroke and gastro-intestinal (GI) bleeding, which adversely impacts treatment outcomes, and causes fatalities. The etiology and mechanisms of these complications can be linked to the fact that LVAD outflow jet leads to an altered state of hemodynamics in the aorta as compared to baseline flow driven by aortic jet during ventricular systole. Here, we presen...
Source: Annals of Biomedical Engineering - January 27, 2023 Category: Biomedical Engineering Authors: Akshita Sahni Erin E McIntyre Jay D Pal Debanjan Mukherjee Source Type: research

Effects of Bilateral Assistance for Hemiparetic Gait Post-Stroke Using a Powered Hip Exoskeleton
In this study, we investigated the effect of different hip exoskeleton assistance strategies on gait function and gait biomechanics of individuals post-stroke. We found that, compared to walking without a device, powered assistance from hip exoskeletons improved stroke participants' self-selected overground walking speed by 17.6 ± 2.5% and 11.1 ± 2.7% with a bilateral and unilateral assistance strategy, respectively (p < 0.05). Furthermore, both bilateral and unilateral assistance strategies significantly increased the paretic and non-paretic step length (p < 0.05). Our findings suggest that powered assistance from...
Source: Annals of Biomedical Engineering - August 13, 2022 Category: Biomedical Engineering Authors: Yi-Tsen Pan Inseung Kang James Joh Patrick Kim Kinsey R Herrin Trisha M Kesar Gregory S Sawicki Aaron J Young Source Type: research