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Source: American Journal of Physiology. Heart and Circulatory Physiology

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Total 253 results found since Jan 2013.

Physical and Physiologic Effects of Dobutamine Stress Echocardiography in Low-Gradient Aortic Stenosis
CONCLUSION: During DSE, aortic valve area increases with increase aortic valve gradient. Higher calcium score is associated with lower baseline aortic valve area, but the area valve area still increases with dobutamine even in presence of high calcium score.PMID:34860593 | DOI:10.1152/ajpheart.00183.2021
Source: American Journal of Physiology. Heart and Circulatory Physiology - December 3, 2021 Category: Physiology Authors: Kimi Sato Tom Kai Ming Wang Milind Y Desai Samir R Kapadia Amar Krishnaswamy L Leonardo Rodriguez Richard A Grimm Brian P Griffin Zoran B Popovic Source Type: research

Resistance but not endurance exercise training induces changes in cerebrovascular function in healthy young subjects
CONCLUSIONS: Our findings, which were consistent across multiple domains of cerebrovascular function, suggest that episodic increases in arterial pressure associated with resistance training may increase cerebrovascular resistance. The implications of long-term resistance training on brain health require future study, especially in populations with pre-existing cerebral hypoperfusion and/or hypotension.PMID:34559581 | DOI:10.1152/ajpheart.00230.2021
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 24, 2021 Category: Physiology Authors: Hannah J Thomas Channa E Marsh Louise H Naylor Philip N Ainslie Kurt J Smith Howard H Carter Daniel J Green Source Type: research

Experimental high thoracic spinal cord injury impairs the cardiac and cerebrovascular response to orthostatic challenge in rats
CONCLUSION: Using a preclinical SCI model of OH, we demonstrate that complete high thoracic SCI impairs the cardiac response to OH and disrupts dynamic cerebral autoregulation.PMID:34448635 | DOI:10.1152/ajpheart.00239.2021
Source: American Journal of Physiology. Heart and Circulatory Physiology - August 27, 2021 Category: Physiology Authors: Brian D Hayes Mary Pauline Mona Fossey Malihe-Sadat Poormasjedi-Meibod Erin Erskine Jan Elaine Soriano Berkeley Scott Ryan Rosentreter David J Granville Aaron A Phillips Christopher R West Source Type: research

Metalloproteinases and Their Inhibitors Are Associated with Pulmonary Arterial Stiffness and Ventricular Function in Pediatric Pulmonary Hypertension
Am J Physiol Heart Circ Physiol. 2021 Jun 4. doi: 10.1152/ajpheart.00750.2020. Online ahead of print.ABSTRACTDisturbed balance between matrix metalloproteinases (MMPs) and their respective tissue inhibitors (TIMPs) is a well-recognized pathophysiologic component of pulmonary arterial hypertension (PAH). Both classes of proteases have been associated with clinical outcomes as well as with specific pathologic features of ventricular dysfunction and pulmonary arterial remodeling. The purpose of this study was to evaluate the circulating levels of MMPs and TIMPs in children with PAH undergoing the same day cardiac MRI and righ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - June 4, 2021 Category: Physiology Authors: Michal Schafer D Dunbar Ivy Kathleen Nguyen Katie L Boncella Benjamin S Frank Gareth J Morgan Kathleen Miller-Reed Uyen Truong Kelley L Colvin Michael E Yeager Source Type: research