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Source: American Journal of Physiology. Heart and Circulatory Physiology

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Total 253 results found since Jan 2013.

Long-term circadian disruption shortens lifespan and dampens blood pressure diurnal rhythms in stroke-prone spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00055.2023. Online ahead of print.ABSTRACTEnvironmental cues such as light and timing of food intake influence molecular clocks that produce circadian rhythmicity of many biological functions. The master circadian clock is entrained by light input and synchronizes to peripheral clocks in every organ. Careers that require rotating shift work schedules predispose workers to a constant desynchronization of biological clocks and are associated with increased risk of cardiovascular disease. We utilized a stroke-prone spontaneously hypertensive rat model exposed...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Anne M Ramsey Adam Stowie Atlantis Hill Ivory Ellis Megan Rhoads David M Pollock Alec J Davidson Source Type: research

Influence of accelerated arterial ageing in growth restricted cohorts on adult-onset cardiovascular diseases
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00134.2023. Online ahead of print.ABSTRACTEpidemiologists have long documented higher risk of adult-onset cardiovascular diseases (CVD) such as stroke, hypertension and coronary artery disease) and mortality from circulatory causes in low birth weight cohorts (poor in utero substrate supply). Utero-placental insufficiency and in utero hypoxemic state induced alterations in arterial structure and compliance are important initiating factors for adult-onset hypertension. The mechanistic links between fetal growth restriction and CVD include decreased arterial...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Arvind Sehgal Beth J Allison F àtima Crispi Samuel Menahem Source Type: research

Long-term circadian disruption shortens lifespan and dampens blood pressure diurnal rhythms in stroke-prone spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00055.2023. Online ahead of print.ABSTRACTEnvironmental cues such as light and timing of food intake influence molecular clocks that produce circadian rhythmicity of many biological functions. The master circadian clock is entrained by light input and synchronizes to peripheral clocks in every organ. Careers that require rotating shift work schedules predispose workers to a constant desynchronization of biological clocks and are associated with increased risk of cardiovascular disease. We utilized a stroke-prone spontaneously hypertensive rat model exposed...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Anne M Ramsey Adam Stowie Atlantis Hill Ivory Ellis Megan Rhoads David M Pollock Alec J Davidson Source Type: research

Influence of accelerated arterial ageing in growth restricted cohorts on adult-onset cardiovascular diseases
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00134.2023. Online ahead of print.ABSTRACTEpidemiologists have long documented higher risk of adult-onset cardiovascular diseases (CVD) such as stroke, hypertension and coronary artery disease) and mortality from circulatory causes in low birth weight cohorts (poor in utero substrate supply). Utero-placental insufficiency and in utero hypoxemic state induced alterations in arterial structure and compliance are important initiating factors for adult-onset hypertension. The mechanistic links between fetal growth restriction and CVD include decreased arterial...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Arvind Sehgal Beth J Allison F àtima Crispi Samuel Menahem Source Type: research

Long-term circadian disruption shortens lifespan and dampens blood pressure diurnal rhythms in stroke-prone spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00055.2023. Online ahead of print.ABSTRACTEnvironmental cues such as light and timing of food intake influence molecular clocks that produce circadian rhythmicity of many biological functions. The master circadian clock is entrained by light input and synchronizes to peripheral clocks in every organ. Careers that require rotating shift work schedules predispose workers to a constant desynchronization of biological clocks and are associated with increased risk of cardiovascular disease. We utilized a stroke-prone spontaneously hypertensive rat model exposed...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Anne M Ramsey Adam Stowie Atlantis Hill Ivory Ellis Megan Rhoads David M Pollock Alec J Davidson Source Type: research

Influence of accelerated arterial ageing in growth restricted cohorts on adult-onset cardiovascular diseases
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00134.2023. Online ahead of print.ABSTRACTEpidemiologists have long documented higher risk of adult-onset cardiovascular diseases (CVD) such as stroke, hypertension and coronary artery disease) and mortality from circulatory causes in low birth weight cohorts (poor in utero substrate supply). Utero-placental insufficiency and in utero hypoxemic state induced alterations in arterial structure and compliance are important initiating factors for adult-onset hypertension. The mechanistic links between fetal growth restriction and CVD include decreased arterial...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Arvind Sehgal Beth J Allison F àtima Crispi Samuel Menahem Source Type: research

Long-term circadian disruption shortens lifespan and dampens blood pressure diurnal rhythms in stroke-prone spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00055.2023. Online ahead of print.ABSTRACTEnvironmental cues such as light and timing of food intake influence molecular clocks that produce circadian rhythmicity of many biological functions. The master circadian clock is entrained by light input and synchronizes to peripheral clocks in every organ. Careers that require rotating shift work schedules predispose workers to a constant desynchronization of biological clocks and are associated with increased risk of cardiovascular disease. We utilized a stroke-prone spontaneously hypertensive rat model exposed...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Anne M Ramsey Adam Stowie Atlantis Hill Ivory Ellis Megan Rhoads David M Pollock Alec J Davidson Source Type: research

Influence of accelerated arterial ageing in growth restricted cohorts on adult-onset cardiovascular diseases
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00134.2023. Online ahead of print.ABSTRACTEpidemiologists have long documented higher risk of adult-onset cardiovascular diseases (CVD) such as stroke, hypertension and coronary artery disease) and mortality from circulatory causes in low birth weight cohorts (poor in utero substrate supply). Utero-placental insufficiency and in utero hypoxemic state induced alterations in arterial structure and compliance are important initiating factors for adult-onset hypertension. The mechanistic links between fetal growth restriction and CVD include decreased arterial...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Arvind Sehgal Beth J Allison F àtima Crispi Samuel Menahem Source Type: research

Long-term circadian disruption shortens lifespan and dampens blood pressure diurnal rhythms in stroke-prone spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00055.2023. Online ahead of print.ABSTRACTEnvironmental cues such as light and timing of food intake influence molecular clocks that produce circadian rhythmicity of many biological functions. The master circadian clock is entrained by light input and synchronizes to peripheral clocks in every organ. Careers that require rotating shift work schedules predispose workers to a constant desynchronization of biological clocks and are associated with increased risk of cardiovascular disease. We utilized a stroke-prone spontaneously hypertensive rat model exposed...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Anne M Ramsey Adam Stowie Atlantis Hill Ivory Ellis Megan Rhoads David M Pollock Alec J Davidson Source Type: research

Influence of accelerated arterial ageing in growth restricted cohorts on adult-onset cardiovascular diseases
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00134.2023. Online ahead of print.ABSTRACTEpidemiologists have long documented higher risk of adult-onset cardiovascular diseases (CVD) such as stroke, hypertension and coronary artery disease) and mortality from circulatory causes in low birth weight cohorts (poor in utero substrate supply). Utero-placental insufficiency and in utero hypoxemic state induced alterations in arterial structure and compliance are important initiating factors for adult-onset hypertension. The mechanistic links between fetal growth restriction and CVD include decreased arterial...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Arvind Sehgal Beth J Allison F àtima Crispi Samuel Menahem Source Type: research

Long-term circadian disruption shortens lifespan and dampens blood pressure diurnal rhythms in stroke-prone spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00055.2023. Online ahead of print.ABSTRACTEnvironmental cues such as light and timing of food intake influence molecular clocks that produce circadian rhythmicity of many biological functions. The master circadian clock is entrained by light input and synchronizes to peripheral clocks in every organ. Careers that require rotating shift work schedules predispose workers to a constant desynchronization of biological clocks and are associated with increased risk of cardiovascular disease. We utilized a stroke-prone spontaneously hypertensive rat model exposed...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Anne M Ramsey Adam Stowie Atlantis Hill Ivory Ellis Megan Rhoads David M Pollock Alec J Davidson Source Type: research

Influence of accelerated arterial ageing in growth restricted cohorts on adult-onset cardiovascular diseases
Am J Physiol Heart Circ Physiol. 2023 May 19. doi: 10.1152/ajpheart.00134.2023. Online ahead of print.ABSTRACTEpidemiologists have long documented higher risk of adult-onset cardiovascular diseases (CVD) such as stroke, hypertension and coronary artery disease) and mortality from circulatory causes in low birth weight cohorts (poor in utero substrate supply). Utero-placental insufficiency and in utero hypoxemic state induced alterations in arterial structure and compliance are important initiating factors for adult-onset hypertension. The mechanistic links between fetal growth restriction and CVD include decreased arterial...
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 19, 2023 Category: Physiology Authors: Arvind Sehgal Beth J Allison F àtima Crispi Samuel Menahem Source Type: research

Sex Differences in Cardiovascular Disease and Dysregulation in Down Syndrome
Am J Physiol Heart Circ Physiol. 2023 Feb 17. doi: 10.1152/ajpheart.00544.2022. Online ahead of print.ABSTRACTThis scoping review and retrospective medical record review is focused on potential sex differences in cardiovascular diseases in patients with Down syndrome. We limited our review to peer-reviewed, primary articles in the English language, in the PubMed and Web of Science databases from 1965-2021. Four categorical domains were identified and searched using additional keywords: 1) congenital heart disease, 2) baseline physiology and risk factors, 3) heart disease and hypertension, and 4) stroke and cerebrovascular ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - February 17, 2023 Category: Physiology Authors: Melissa L Bates Anastasiia Vasileva Laura D M Flores Yana Pryakhina Michelle Buckman Michael H Tomasson Lara R DeRuisseau Source Type: research