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Current Perspectives regarding Stem Cell-based Therapy for Ischemic Stroke.
Abstract Stroke is a leading cause of death and disability worldwide. Conventional treatment has a limitation of very narrow therapeutic time window and its devastating nature necessitate a novel regenerative approach. Transplanted stem cells resulted in functional recovery through multiple mechanisms including neuroprotection, neurogenesis, angiogenesis, immunomodulation, and anti-inflammatory effects. Despite the promising features shown in experimental studies, results from clinical trials are inconclusive from the perspective of efficacy. The present review presents a synopsis of stem cell research on ischemic...
Source: Current Pharmaceutical Design - June 3, 2018 Category: Drugs & Pharmacology Authors: Park YS, Lee JW, Kwon HB, Kwak KA Tags: Curr Pharm Des Source Type: research