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Source: IEE Transactions on Neural Systems and Rehabilitation Engineering
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Total 279 results found since Jan 2013.
Exoskeleton-Assisted Sit-to-Stand Training Improves Lower-Limb Function Through Modifications of Muscle Synergies in Subacute Stroke Survivors
Abnormal muscle synergies during sit-to-stand (STS) transitions have been observed post-stroke, which are associated with deteriorated lower-limb function and mobility. Although exoskeletons have been used in restoring lower-limb function, their effects on muscle synergies and lower-limb motor recovery remain unclear. Here, we characterized normal muscle synergy patterns during STS activity in ten healthy adults as a reference, comparing with pathological muscle synergy patterns in ten participants with subacute stroke. Moreover, we assessed the effects of a 3-week exoskeleton-assisted STS training intervention on muscle s...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - August 4, 2023 Category: Neuroscience Source Type: research
Reorganization of Motor Execution Networks During Sub-Acute Phase After Stroke
In this study, functional magnetic resonance imaging data were collected from twelve stroke patients during blocked finger-tapping task at four post-stroke time points (less than 10 days, around 2 weeks, 1 month and 3 months), respectively. The dynamic changes and prognostic value of the network parameters (i.e., topological parameters, functional connectivity and nodal parameters) in task-state motor execution networks were thoroughly evaluated. We found that the topological configuration (clustering coefficient and characteristic path length) of task-state motor execution networks underwent significant shift during strok...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - July 1, 2015 Category: Neuroscience Source Type: research
A Boosting-Based Spatial-Spectral Model for Stroke Patients’ EEG Analysis in Rehabilitation Training
Studies have shown that a motor imagery electro encephalogram (EEG)-based brain-computer interface (BCI) system can be used as a rehabilitation tool for stroke patients. Efficient classification of EEG from stroke patients is fundamental in the BCI-based stroke rehabilitation systems. One of the most successful algorithms for EEG classification is the common spatial patterns (CSP). However, studies have reported that the performance of CSP heavily relies on its operational frequency band and channels configuration. To the best of our knowledge, there is no agreed upon clinical conclusion about motor imagery patterns of str...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - January 1, 2016 Category: Neuroscience Source Type: research
Effects of Transcranial Direct Current Stimulation (tDCS) Combined With Wrist Robot-Assisted Rehabilitation on Motor Recovery in Subacute Stroke Patients: A Randomized Controlled Trial
Both transcranial direct current stimulation (tDCS) and wrist robot-assisted training have demonstrated to be promising approaches for stroke rehabilitation. However, the effects of the combination of the two treatments in subacute stroke patients are not clear yet. To investigate the effectiveness of combining tDCS and wrist robot-assisted rehabilitation in subacute stroke patients in comparison with the wrist robotic training only, a single-blind, randomized, sham-controlled trial was performed with 40 subacute stroke patients (25 ± 7 days from stroke onset time). Patients were randomly assigned to experimental gr...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - June 30, 2019 Category: Neuroscience Source Type: research
Quantifying Altered Neural Connectivity of the Stretch Reflex in Chronic Hemiparetic Stroke
This study provides new evidence of changes in neural connectivity and long-latency time lag in the stretch reflex response post-stroke. The results suggest the contribution of indirect motor pathways to synergy-related spasticity.
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - May 31, 2020 Category: Neuroscience Source Type: research
Effects of Transcranial Direct Current Stimulation on EEG Power and Brain Functional Network in Stroke Patients
Transcranial direct current stimulation (tDCS) has become a new method of rehabilitation treatment for stroke and is gradually gaining acceptance. However, the neurophysiological mechanisms of tDCS in the treatment of stroke still need to be further explored. In our research, we aimed to investigate the effects of tDCS on neural oscillation power and brain functional network (BFN) connectivity in stroke patients based on electroencephalogram (EEG). Fifteen patients with ischemic stroke attended two experimental sessions in a randomized crossover trial and received real and sham tDCS. Resting-state EEG signals were acquired...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - February 3, 2023 Category: Neuroscience Source Type: research
Effect of Early and Late Rehabilitation Onset in a Chronic Rat Model of Ischemic Stroke— Assessment of Motor Cortex Signaling and Gait Functionality Over Time
The aim of the present study was to investigate the effects of ischemic stroke and onset of subsequent rehabilitation of gait function in rats. Nine male Sprague-Dawley rats were instrumented with a 16-channel intracortical (IC) electrode array. An ischemic stroke was induced within the hindlimb area of the left motor cortex. The rehabilitation consisted of a repetitive training paradigm over 28 days, initiated on day one (“Early-onset”, 5 rats) and on day seven, (“Late-onset”, 4 rats). Data were obtained from IC microstimulation tests, treadmill walking tests, and beam walking tests. Results re...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - November 1, 2013 Category: Neuroscience Source Type: research
Assist-as-Needed Robot-Aided Gait Training Improves Walking Function in Individuals Following Stroke
A novel robot-aided assist-as-needed gait training paradigm has been developed recently. This paradigm encourages subjects' active participation during training. Previous pilot studies demonstrated that assist-as-needed robot-aided gait training (RAGT) improves treadmill walking performance post-stroke. However, it is not known if there is an over-ground transfer of the training effects from RAGT on treadmill or long-term retention of the effects. The purpose of the current study was to examine the effects of assist-as-needed RAGT on over-ground walking pattern post-stroke. Nine stroke subjects received RAGT with vi...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - November 1, 2015 Category: Neuroscience Source Type: research
Data Glove System Embedded With Inertial Measurement Units for Hand Function Evaluation in Stroke Patients
This paper proposes a data glove system integrated with six-axis inertial measurement unit sensors for evaluating the hand function of patients who have suffered a stroke. The modular design of this data glove facilitates its use for stroke patients. The proposed system can use the hand’s accelerations, angular velocities, and joint angles as calculated by a quaternion algorithm, to help physicians gain new insights into rehabilitation treatments. A clinical experiment was performed on 15 healthy subjects and 15 stroke patients whose Brunnstrom stages (BSs) ranged from 4 to 6. In this experiment, the participants we...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - November 1, 2017 Category: Neuroscience Source Type: research
Synergy-Based FES for Post-Stroke Rehabilitation of Upper-Limb Motor Functions
Functional electrical stimulation (FES) is capable of activating muscles that are under-recruited in neurological diseases, such as stroke. Therefore, FES provides a promising technology for assisting upper-limb motor functions in rehabilitation following stroke. However, the full benefits of FES may be limited due to lack of a systematic approach to formulate the pattern of stimulation. Our preliminary work demonstrated that it is feasible to use muscle synergy to guide the generation of FES patterns.In this paper, we present a methodology of formulating FES patterns based on muscle synergies of a normal subject using a p...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - February 1, 2019 Category: Neuroscience Source Type: research
The Step Response in Isometric Grip Force Tracking: A Model to Characterize Aging- and Stroke-Induced Changes
This paper aimed to construct a model to represent dynamic motor behavior to quantitatively investigate aging- and stroke-induced changes and, thus, to explore the underlying mechanisms of grip control. Grip force tracking tasks were conducted by stroke patients, age-matched healthy controls, and healthy young adults at 25%, 50%, and 75% maximum voluntary contractions (MVC), respectively. Sensorimotor control of the tracking task was modeled as the step response of a second-order system. The results revealed that aging had no significant effect on the parameters of the model, whereas significant differ...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 31, 2019 Category: Neuroscience Source Type: research
Robot-Assisted Reaching Performance of Chronic Stroke and Healthy Individuals in a Virtual Versus a Physical Environment: A Pilot Study
The aim of the current study was to examine the role of environment, whether virtual or physical, on robot-assisted reaching movements in chronic stroke and healthy individuals, within a single session. Twenty-three subjects participated in the current study divided into three groups: nine chronic stroke individuals able to perform a reaching task with no need for the robot assistance, nine chronic stroke individuals who needed robot assistance to complete the reaching task, and five healthy individuals. The task was to reach six target buttons in two identical physical and virtual environments. The outcomes consisted of s...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - May 31, 2019 Category: Neuroscience Source Type: research
Kinematic Validity of Reaching in a 2D Virtual Environment for Arm Rehabilitation After Stroke
Increasing evidence supports the use of virtual reality for stroke rehabilitation. However, movement performance and quality may be diminished by the attributes of the virtual environment (VE), which may be detrimental to motor relearning. Our aim was to determine whether reach-to-grasp movements made in a low-cost 2DVE were kinematically similar to those made in a comparable physical environment (PE) in healthy subjects and subjects with stroke. Subjects (healthy = 15, stroke = 22) made unilateral and bilateral reach-to-grasp movements in a 2DVE and a similar PE. Arm and trunk kinematics were recorded with a...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - February 29, 2020 Category: Neuroscience Source Type: research
Real-Time Avatar-Based Feedback to Enhance the Symmetry of Spatiotemporal Parameters After Stroke: Instantaneous Effects of Different Avatar Views
Gait asymmetry, one of the hallmarks of post stroke locomotion, often persists despite gait rehabilitation interventions, impacting negatively on functional mobility. Real-time feedback and biological cues have been studied extensively in recent years, but their applicability to post-stroke gait symmetry remain questionable. This proof-of-concept study examined the feasibility and instantaneous effects of real-time visual feedback provided in the form of an avatar in twelve participants with stroke on gait symmetry and other gait-related outcomes. The visual avatar was presented via three different views from the back, fro...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 31, 2020 Category: Neuroscience Source Type: research
Deep Cerebellar Low-Intensity Focused Ultrasound Stimulation Restores Interhemispheric Balance after Ischemic Stroke in Mice
Ischemic damage after stroke disrupts the complex balance of inhibitory and excitatory activity within cortical network causing brain functional asymmetry. Cerebellar deep nuclei with its extensive projections to cortical regions could be a prospective target for stimulation to restore inter-hemispheric balance and enhance neural plasticity after stroke. In our study, we repeatedly stimulated the lateral cerebellar nucleus (LCN) by low-intensity focused ultrasound (LIFU) for 3 days to enhance rehabilitation after middle cerebral artery occlusion (MCAO) in a mouse stroke model. The neural activity of the mice sensorimotor c...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - August 31, 2020 Category: Neuroscience Source Type: research
