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Management of Direct Oral Anticoagulants in the Perioperative Setting
AN INCREASING NUMBER of patients undergoing surgical procedures are treated chronically by oral anticoagulants (OAC). Vitamin K antagonists (VKAs) have been standard practice in chronic anticoagulant therapy for decades. Despite a proved efficacy, they have several disadvantages. Over the past 5 years, direct oral anticoagulants (DOAs) such as dabigatran, rivaroxaban, apixaban, and edoxaban have been approved for several indications for long-term anticoagulation. Consequently, with the aging population and the extension of the indication of anticoagulation for stroke prevention in nonvalvular atrial fibrillation (AF), ther...
Source: Journal of Cardiothoracic and Vascular Anesthesia - May 24, 2015 Category: Anesthesiology Authors: Olivier Untereiner, Pierre-François Seince, Vladimir Chterev, Isabelle Leblanc, Clarisse Berroëta, Patrick Bourel, Ivan Philip Tags: Review ArticlesGiovanni Landoni, MDSection Editors? > Source Type: research