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Computer Aided Reverse Vaccinology: A Game-changer Approach for Vaccine Development
Comb Chem High Throughput Screen. 2022 Sep 30. doi: 10.2174/1386207325666220930124013. Online ahead of print.ABSTRACTOne of the most dynamic approaches in biotechnology is reverse vaccinology, which plays a huge role in today's developing vaccines. It has the capability of exploring and identifying the most potent vaccine candidate in a limited period of time. The first successful novel approach of reverse vaccinology was observed in Neisseria meningitidis serogroup B, which has revolutionised the whole field of computational biology. In this review, we have summarized the application of reverse vaccinology for different i...
Source: Combinatorial Chemistry and High Throughput Screening - October 6, 2022 Category: Chemistry Authors: Poornima Srivastava Chakresh Kumar Jain Source Type: research

Neglected Tropical Diseases (NTDs) and COVID-19 pandemic in Africa: Special focus on control strategies
Comb Chem High Throughput Screen. 2022 Apr 27. doi: 10.2174/1386207325666220427123349. Online ahead of print.ABSTRACTNeglected Tropical Diseases (NTDs) are a group of twenty (20) chronic, communicable, infectious diseases endemic to the tropics and sub-tropics climate countries which are intimately associated with poverty, poor sanitation, limited clean water, and healthcare delivery; and dwellers live in proximity to pathogens and diseases vectors. The pathogens are protozoans, bacteria, helminths, fungi, and viruses. NTDs currently affects about one billion people globally, out of which 500 million are Africans living in...
Source: Combinatorial Chemistry and High Throughput Screening - May 1, 2022 Category: Chemistry Authors: Abdullahi Tunde Aborode Emmanuel Adebowale Fajemisin Emmanuel Ademola Aiyenuro Muhammad Alakitan Matthew Olaide Ariwoola Jegede Oluwatoyin Imisioluwa Raheemt Rafiu Athanasios Alexiou Source Type: research