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Source: Acta Neurobiologiae Experimentalis
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Total 638 results found since Jan 2013.
Anodal transcranial direct current stimulation with monopolar pulses improves limb use after stroke by enhancing inter-hemispheric coherence.
Abstract
Post-stroke neurological deficits, such as sensorimotor impairments, are often permanent and a leading cause of disability. Stroke is also associated with changes in neuronal synchrony among different brain areas. Multiple studies demonstrated that non-invasive brain stimulation, such as transcranial direct current stimulation (tDCS), enhances the efficacy of existing rehabilitative therapies. We hypothesized that the therapeutic effects of tDCS could be due to its influence on neuronal synchrony. To study this, we recorded local field potentials in rats treated with anodal tDCS (a-tDCS) after unilateral ...
Source: Acta Neurobiologiae Experimentalis - October 8, 2019 Category: Neurology Authors: Schjetnan AG, Gidyk DC, Metz GA, Luczak A Tags: Acta Neurobiol Exp (Wars) Source Type: research
LACC1 contributes to inflammation and cognitive disorder after stroke via the AMPK/NLRP3 pathway
Acta Neurobiol Exp (Wars). 2022;82(2):207-212. doi: 10.55782/ane-2022-019.ABSTRACTThe current study aimed to investigate the effects of LACC1 on cognitive disorder due to stroke, as well as its underlying mechanism. LACC1 promoted inflammation and aggravated cognitive impairment in a mouse model of stroke. In an in vitro model of stroke, inhibition of LACC1 reduced inflammation and ROS‑induced oxidative stress by activating AMP‑activated protein kinase (AMPK) expression and suppressing NLPR3 expression. Furthermore, our studies revealed that inhibition of AMPK activity reduced the effects of si‑LACC1 on cognitive dis...
Source: Acta Neurobiologiae Experimentalis - July 14, 2022 Category: Neurology Authors: Junping Jiao Shujuan Tian Junqiang Bao Zhiwei Wang Xiongwei Xie Guofeng Yang Source Type: research
