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Source: Neural Plasticity

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Total 410 results found since Jan 2013.

Rodent Models of Developmental Ischemic Stroke for Translational Research: Strengths and Weaknesses.
Abstract Cerebral ischemia can occur at any stage in life, but clinical consequences greatly differ depending on the developmental stage of the affected brain structures. Timing of the lesion occurrence seems to be critical, as it strongly interferes with neuronal circuit development and determines the way spontaneous plasticity takes place. Translational stroke research requires the use of animal models as they represent a reliable tool to understand the pathogenic mechanisms underlying the generation, progression, and pathological consequences of a stroke. Moreover, in vivo experiments are instrumental to invest...
Source: Neural Plasticity - May 18, 2019 Category: Neurology Authors: Gennaro M, Mattiello A, Pizzorusso T Tags: Neural Plast Source Type: research

Hypertension and Its Impact on Stroke Recovery: From a Vascular to a Parenchymal Overview.
Abstract Hypertension is the first modifiable vascular risk factor accounting for 10.4 million deaths worldwide; it is strongly and independently associated with the risk of stroke and is related to worse prognosis. In addition, hypertension seems to be a key player in the implementation of vascular cognitive impairment. Long-term hypertension, complicated or not by the occurrence of ischemic stroke, is often reviewed on its vascular side, and parenchymal consequences are put aside. Here, we sought to review the impact of isolated hypertension or hypertension associated to stroke on brain atrophy, neuron connectiv...
Source: Neural Plasticity - November 19, 2019 Category: Neurology Authors: Maïer B, Kubis N Tags: Neural Plast Source Type: research

Does Measurement of Corticospinal Tract Involvement Add Value to Clinical Behavioral Biomarkers in Predicting Motor Recovery after Stroke?
Conclusions: Motor recovery of the upper and lower extremities after stroke could be predicted using the initial FMA score. CST injury was significant for the prediction of motor recovery of the upper extremity in patients with severe initial motor deficits (FMA-UE < 35); however, its portion of prediction of motor recovery was low. The prediction of poststroke motor recovery using the initial motor deficit was not improved by the addition of CST injury measurements. PMID: 33354207 [PubMed - in process]
Source: Neural Plasticity - December 30, 2020 Category: Neurology Authors: Lim JY, Oh MK, Park J, Paik NJ Tags: Neural Plast Source Type: research

Effect of Cognitive Function on Balance and Posture Control after Stroke.
Abstract Hemiplegic gait is the most common sequela of stroke. Patients with hemiplegic gait are at a risk of falling because of poor balance. The theory of cognitive-motor networks paved the way for a new field of research. However, the mechanism of the relationship of cognition with gait or posture control networks is unclear because of the dynamic characteristics of walking and changing postures. To explore differences in the balance function and fall risk between patients with and without cognitive impairment after stroke, we utilized the Berg balance scale, Timed "Up and Go" test, and 10 m walking test. Pat...
Source: Neural Plasticity - February 14, 2021 Category: Neurology Authors: Yu HX, Wang ZX, Liu CB, Dai P, Lan Y, Xu GQ Tags: Neural Plast Source Type: research

Effect of Acupuncture on Neuroplasticity of Stroke Patients with Motor Dysfunction: A Meta-Analysis of fMRI Studies
CONCLUSION: Acupuncture plays a role in promoting neuroplasticity in subcortical regions that are commonly affected by stroke and cortical motor areas that may compensate for motor deficits, which may provide a possible mechanism underlying the therapeutic effect of acupuncture.PMID:34188677 | PMC:PMC8192216 | DOI:10.1155/2021/8841720
Source: Neural Plasticity - June 30, 2021 Category: Neurology Authors: Qiuyi Lv Guixing Xu Yuxin Pan Tongtong Liu Xiaodong Liu Linqing Miao Xing Chen Lan Jiang Jie Chen Yingjia He Rong Zhang Yihuai Zou Source Type: research

Neuroplasticity of Acupuncture for Stroke: An Evidence-Based Review of MRI
Neural Plast. 2021 Aug 19;2021:2662585. doi: 10.1155/2021/2662585. eCollection 2021.ABSTRACTAcupuncture is widely recognized as a potentially effective treatment for stroke rehabilitation. Researchers in this area are actively investigating its therapeutic mechanisms. Magnetic resonance imaging (MRI), as a noninvasive, high anatomical resolution technique, has been employed to investigate neuroplasticity on acupuncture in stroke patients from a system level. However, there is no review on the mechanism of acupuncture treatment for stroke based on MRI. Therefore, we aim to summarize the current evidence about this aspect an...
Source: Neural Plasticity - August 30, 2021 Category: Neurology Authors: Jinhuan Zhang Chunjian Lu Xiaoxiong Wu Dehui Nie Haibo Yu Source Type: research

Deep Sequencing of the Rat MCAO Cortexes Reveals Crucial circRNAs Involved in Early Stroke Events and Their Regulatory Networks
Neural Plast. 2021 Nov 24;2021:9942537. doi: 10.1155/2021/9942537. eCollection 2021.ABSTRACTCircular RNAs (circRNAs) are highly enriched in the central nervous system and significantly involved in a range of brain-related physiological and pathological processes. Ischemic stroke is a complex disorder caused by multiple factors; however, whether brain-derived circRNAs participate in the complex regulatory networks involved in stroke pathogenesis remains unknown. Here, we successfully constructed a cerebral ischemia-injury model of middle cerebral artery occlusion (MCAO) in male Sprague-Dawley rats. Preliminary qualitative a...
Source: Neural Plasticity - December 6, 2021 Category: Neurology Authors: Chengtan Wang Yuying Yang Mengsi Xu Fuxiu Mao Peng Yang Shan Yuan Rui Gao Shangquan Gan Source Type: research

Effectiveness of a Novel Contralaterally Controlled Neuromuscular Electrical Stimulation for Restoring Lower Limb Motor Performance and Activities of Daily Living in Stroke Survivors: A Randomized Controlled Trial
CONCLUSION: CCNMES improved motor function and ADL ability to a greater extent than the conventional NMES in subacute stroke patients.PMID:35069728 | PMC:PMC8767388 | DOI:10.1155/2022/5771634
Source: Neural Plasticity - January 24, 2022 Category: Neurology Authors: Ying Shen Lan Chen Li Zhang Shugang Hu Bin Su Huaide Qiu Xingjun Xu Guilan Huang Zhifei Yin Jinyu Yang Chuan Guo Tong Wang Source Type: research