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Source: Neural Plasticity
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Total 410 results found since Jan 2013.
Muscle Fiber Diameter and Density Alterations after Stroke Examined by Single-Fiber EMG
This study presents single-fiber electromyography (EMG) analysis for assessment of paretic muscle changes after stroke. Single-fiber action potentials (SFAPs) were recorded from the first dorsal interosseous (FDI) muscle bilaterally in 12 individuals with hemiparetic stroke. The SFAP parameters, including the negative peak duration and the peak-peak amplitude, were measured and further used to estimate muscle fiber diameter through a model based on the quadratic function. The SFAP parameters, fiber density, and muscle fiber diameter derived from the model were compared between the paretic and contralateral muscles. The res...
Source: Neural Plasticity - August 26, 2021 Category: Neurology Authors: Chengjun Huang Bo Yao Xiaoyan Li Sheng Li Ping Zhou Source Type: research
A New Classification System for Postinterventional Cerebral Hyperdensity: The Influence on Hemorrhagic Transformation and Clinical Prognosis in Acute Stroke
CONCLUSION: The relationship of PCHD and HT suggested PCHD was an early risk indicator for HT. The occurrence of PCHD-3 and PCHD-4 was a strong predictor for END. PCHD-1 is considered to be relatively benign in relation to the 3-month mRS.PMID:34858495 | PMC:PMC8632469 | DOI:10.1155/2021/6144304
Source: Neural Plasticity - December 3, 2021 Category: Neurology Authors: Yuan Shao Yuyun Xu Yumei Li Xuehua Wen Xiaodong He Source Type: research
Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice
CONCLUSION: r-hGH increases pro-BDNF within the peri-infarct area and regions that are known to experience secondary neurodegeneration after stroke. Upregulation of total-mTOR protein expression in the peri-infarct and thalamus suggests that this might be a pathway that is involved in the neurorestorative effects previously reported in these animals and warrants further investigation. These findings suggest region-specific mechanisms of action of GH treatment and provide further understanding for how GH treatment promotes neurorestorative effects after stroke.PMID:35465399 | PMC:PMC9033347 | DOI:10.1155/2022/9983042
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Sonia Sanchez-Bezanilla Daniel J Beard Rebecca J Hood N David Åberg Patricia Crock Frederick R Walker Michael Nilsson J örgen Isgaard Lin Kooi Ong Source Type: research
Cognitive Dysfunction following Cerebellar Stroke: Insights Gained from Neuropsychological and Neuroimaging Research
Neural Plast. 2022 Apr 15;2022:3148739. doi: 10.1155/2022/3148739. eCollection 2022.ABSTRACTAlthough the cerebellum has been consistently noted in the process of cognition, the pathophysiology of this link is still under exploration. Cerebellar stroke, in which the lesions are focal and limited, provides an appropriate clinical model disease for studying the role of the cerebellum in the cognitive process. This review article targeting the cerebellar stroke population (1) describes a cognitive impairment profile, (2) identifies the cerebellar structural alterations linked to cognition, and (3) reveals possible mechanisms o...
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Qi Liu Chang Liu Yu Chen Yumei Zhang Source Type: research
Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice
CONCLUSION: r-hGH increases pro-BDNF within the peri-infarct area and regions that are known to experience secondary neurodegeneration after stroke. Upregulation of total-mTOR protein expression in the peri-infarct and thalamus suggests that this might be a pathway that is involved in the neurorestorative effects previously reported in these animals and warrants further investigation. These findings suggest region-specific mechanisms of action of GH treatment and provide further understanding for how GH treatment promotes neurorestorative effects after stroke.PMID:35465399 | PMC:PMC9033347 | DOI:10.1155/2022/9983042
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Sonia Sanchez-Bezanilla Daniel J Beard Rebecca J Hood N David Åberg Patricia Crock Frederick R Walker Michael Nilsson J örgen Isgaard Lin Kooi Ong Source Type: research
Cognitive Dysfunction following Cerebellar Stroke: Insights Gained from Neuropsychological and Neuroimaging Research
Neural Plast. 2022 Apr 15;2022:3148739. doi: 10.1155/2022/3148739. eCollection 2022.ABSTRACTAlthough the cerebellum has been consistently noted in the process of cognition, the pathophysiology of this link is still under exploration. Cerebellar stroke, in which the lesions are focal and limited, provides an appropriate clinical model disease for studying the role of the cerebellum in the cognitive process. This review article targeting the cerebellar stroke population (1) describes a cognitive impairment profile, (2) identifies the cerebellar structural alterations linked to cognition, and (3) reveals possible mechanisms o...
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Qi Liu Chang Liu Yu Chen Yumei Zhang Source Type: research
Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice
CONCLUSION: r-hGH increases pro-BDNF within the peri-infarct area and regions that are known to experience secondary neurodegeneration after stroke. Upregulation of total-mTOR protein expression in the peri-infarct and thalamus suggests that this might be a pathway that is involved in the neurorestorative effects previously reported in these animals and warrants further investigation. These findings suggest region-specific mechanisms of action of GH treatment and provide further understanding for how GH treatment promotes neurorestorative effects after stroke.PMID:35465399 | PMC:PMC9033347 | DOI:10.1155/2022/9983042
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Sonia Sanchez-Bezanilla Daniel J Beard Rebecca J Hood N David Åberg Patricia Crock Frederick R Walker Michael Nilsson J örgen Isgaard Lin Kooi Ong Source Type: research
Cognitive Dysfunction following Cerebellar Stroke: Insights Gained from Neuropsychological and Neuroimaging Research
Neural Plast. 2022 Apr 15;2022:3148739. doi: 10.1155/2022/3148739. eCollection 2022.ABSTRACTAlthough the cerebellum has been consistently noted in the process of cognition, the pathophysiology of this link is still under exploration. Cerebellar stroke, in which the lesions are focal and limited, provides an appropriate clinical model disease for studying the role of the cerebellum in the cognitive process. This review article targeting the cerebellar stroke population (1) describes a cognitive impairment profile, (2) identifies the cerebellar structural alterations linked to cognition, and (3) reveals possible mechanisms o...
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Qi Liu Chang Liu Yu Chen Yumei Zhang Source Type: research
Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice
CONCLUSION: r-hGH increases pro-BDNF within the peri-infarct area and regions that are known to experience secondary neurodegeneration after stroke. Upregulation of total-mTOR protein expression in the peri-infarct and thalamus suggests that this might be a pathway that is involved in the neurorestorative effects previously reported in these animals and warrants further investigation. These findings suggest region-specific mechanisms of action of GH treatment and provide further understanding for how GH treatment promotes neurorestorative effects after stroke.PMID:35465399 | PMC:PMC9033347 | DOI:10.1155/2022/9983042
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Sonia Sanchez-Bezanilla Daniel J Beard Rebecca J Hood N David Åberg Patricia Crock Frederick R Walker Michael Nilsson J örgen Isgaard Lin Kooi Ong Source Type: research
Cognitive Dysfunction following Cerebellar Stroke: Insights Gained from Neuropsychological and Neuroimaging Research
Neural Plast. 2022 Apr 15;2022:3148739. doi: 10.1155/2022/3148739. eCollection 2022.ABSTRACTAlthough the cerebellum has been consistently noted in the process of cognition, the pathophysiology of this link is still under exploration. Cerebellar stroke, in which the lesions are focal and limited, provides an appropriate clinical model disease for studying the role of the cerebellum in the cognitive process. This review article targeting the cerebellar stroke population (1) describes a cognitive impairment profile, (2) identifies the cerebellar structural alterations linked to cognition, and (3) reveals possible mechanisms o...
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Qi Liu Chang Liu Yu Chen Yumei Zhang Source Type: research
Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice
CONCLUSION: r-hGH increases pro-BDNF within the peri-infarct area and regions that are known to experience secondary neurodegeneration after stroke. Upregulation of total-mTOR protein expression in the peri-infarct and thalamus suggests that this might be a pathway that is involved in the neurorestorative effects previously reported in these animals and warrants further investigation. These findings suggest region-specific mechanisms of action of GH treatment and provide further understanding for how GH treatment promotes neurorestorative effects after stroke.PMID:35465399 | PMC:PMC9033347 | DOI:10.1155/2022/9983042
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Sonia Sanchez-Bezanilla Daniel J Beard Rebecca J Hood N David Åberg Patricia Crock Frederick R Walker Michael Nilsson J örgen Isgaard Lin Kooi Ong Source Type: research
Cognitive Dysfunction following Cerebellar Stroke: Insights Gained from Neuropsychological and Neuroimaging Research
Neural Plast. 2022 Apr 15;2022:3148739. doi: 10.1155/2022/3148739. eCollection 2022.ABSTRACTAlthough the cerebellum has been consistently noted in the process of cognition, the pathophysiology of this link is still under exploration. Cerebellar stroke, in which the lesions are focal and limited, provides an appropriate clinical model disease for studying the role of the cerebellum in the cognitive process. This review article targeting the cerebellar stroke population (1) describes a cognitive impairment profile, (2) identifies the cerebellar structural alterations linked to cognition, and (3) reveals possible mechanisms o...
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Qi Liu Chang Liu Yu Chen Yumei Zhang Source Type: research
Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice
CONCLUSION: r-hGH increases pro-BDNF within the peri-infarct area and regions that are known to experience secondary neurodegeneration after stroke. Upregulation of total-mTOR protein expression in the peri-infarct and thalamus suggests that this might be a pathway that is involved in the neurorestorative effects previously reported in these animals and warrants further investigation. These findings suggest region-specific mechanisms of action of GH treatment and provide further understanding for how GH treatment promotes neurorestorative effects after stroke.PMID:35465399 | PMC:PMC9033347 | DOI:10.1155/2022/9983042
Source: Neural Plasticity - April 25, 2022 Category: Neurology Authors: Sonia Sanchez-Bezanilla Daniel J Beard Rebecca J Hood N David Åberg Patricia Crock Frederick R Walker Michael Nilsson J örgen Isgaard Lin Kooi Ong Source Type: research
