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Source: International Journal of Molecular Medicine
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Total 2185 results found since Jan 2013.
Retracted Inhibition airway remodeling and transforming growth factor ‑β1/Smad signaling pathway by astragalus extract in asthmatic mice
Int J Mol Med. 2023 Oct;52(4):87. doi: 10.3892/ijmm.2023.5290. Epub 2023 Aug 18.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the P‑smad2 western blotting data shown in Fig. 7 were strikingly similar to data appearing in different form (namely, the bands appeared in the reverse orientation) in Fig. 4A in another article [Lv Z‑D, Na D, Liu F‑N, Du Z‑M, Sun Z, Li Z, Ma X‑Y, Wang Z‑N and Xu H‑M: Induction of gastric cancer cell adhesion through transforming growth factor‑beta1‑mediated peritoneal fibrosis. J Exp Clin Cancer Res 29: 139, 201...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Zheng-Hai Qu Zhao-Chuan Yang Lei Chen Zhi-Dong Lv Ming-Ji Yi Ni Ran Source Type: research
Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review)
Int J Mol Med. 2023 Oct;52(4):88. doi: 10.3892/ijmm.2023.5291. Epub 2023 Aug 18.ABSTRACTFerroptosis is a novel form of regulated cellular necrosis that plays a critical role in promoting cancer progression and developing drug resistance. The main characteristic of ferroptosis is iron‑dependent lipid peroxidation caused by excess intracellular levels of reactive oxygen species. CUGBP ELAV‑like family number 2 (CELF2) is an RNA‑binding protein that is downregulated in various types of cancer and is associated with poor patient prognoses. CELF2 can directly bind mRNA to a variety of ferroptosis control factors; however,...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Jiahao Li Lei Xian Zifeng Zhu Yang Wang Wenlei Zhang Ruipeng Zheng Wang Xue Jiarui Li Source Type: research
Corrigendum Carvacrol may alleviate vascular inflammation in diabetic db/db mice
Int J Mol Med. 2023 Oct;52(4):90. doi: 10.3892/ijmm.2023.5293. Epub 2023 Aug 18.ABSTRACTFollowing the publication of the above article, the authors contacted the Editorial Office to explain that they made a couple of inadvertent errors in the assembly of the data panels showing the results of immunohistochemical experiments in Fig. 5K on p. 983 (the 'TLR4' experiments); essentially, the data panels selected for the '10 mg/mg Carvacrol' and '5 mg/kg Carvacrol' experiments were copied across from those shown for the 'NF‑κB' experiments in the row above (Fig. 5I). The revised version of Fig. 5, showing the correct data for...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Wei Zhao Chunyan Deng Qizhen Han Hansong Xu Yonghua Chen Source Type: research
< em > Toxoplasma gondii < /em > excretory/secretory proteins promotes osteogenic differentiation of bone marrow mesenchymal stem cells via aerobic glycolysis mediated by Wnt/ β‑catenin signaling pathway
In conclusion, the present study uncovered the potential mechanism by which TgESPs regulate BMSCs, which will provide a theoretical reference for the study of the function of TgESPs in the future.PMID:37594122 | DOI:10.3892/ijmm.2023.5294
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Weiqiang Zhan Juanhua Quan Zhuming Chen Tianfeng Liu Mingzhu Deng Ziquan Zhao Xuyang Wu Zhuolan Zhong Feifei Gao Jiaqi Chu Source Type: research
Predictive value of the sFlt ‑1/PlGF ratio in women with suspected preeclampsia: An update (Review)
Int J Mol Med. 2023 Oct;52(4):89. doi: 10.3892/ijmm.2023.5292. Epub 2023 Aug 18.ABSTRACTPreeclampsia (PE) is a major complication of pregnancy with an incidence rate of 2‑8% and is a leading cause of maternal mortality and morbidity. The various consequences of severe preeclampsia for the fetus, neonate and child include intrauterine growth retardation (IUGR), fetal hypoxia, oligohydramnios, intrauterine fetal demise, increased perinatal mortality and morbidity, neurodevelopmental disorders and even irreversible brain damage (cerebral palsy). A number of studies have demonstrated that differences in maternal serum concen...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Alexandros Velegrakis Elisavet Kouvidi Persefoni Fragkiadaki Stavros Sifakis Source Type: research
Retracted Inhibition airway remodeling and transforming growth factor ‑β1/Smad signaling pathway by astragalus extract in asthmatic mice
Int J Mol Med. 2023 Oct;52(4):87. doi: 10.3892/ijmm.2023.5290. Epub 2023 Aug 18.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the P‑smad2 western blotting data shown in Fig. 7 were strikingly similar to data appearing in different form (namely, the bands appeared in the reverse orientation) in Fig. 4A in another article [Lv Z‑D, Na D, Liu F‑N, Du Z‑M, Sun Z, Li Z, Ma X‑Y, Wang Z‑N and Xu H‑M: Induction of gastric cancer cell adhesion through transforming growth factor‑beta1‑mediated peritoneal fibrosis. J Exp Clin Cancer Res 29: 139, 201...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Zheng-Hai Qu Zhao-Chuan Yang Lei Chen Zhi-Dong Lv Ming-Ji Yi Ni Ran Source Type: research
Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review)
Int J Mol Med. 2023 Oct;52(4):88. doi: 10.3892/ijmm.2023.5291. Epub 2023 Aug 18.ABSTRACTFerroptosis is a novel form of regulated cellular necrosis that plays a critical role in promoting cancer progression and developing drug resistance. The main characteristic of ferroptosis is iron‑dependent lipid peroxidation caused by excess intracellular levels of reactive oxygen species. CUGBP ELAV‑like family number 2 (CELF2) is an RNA‑binding protein that is downregulated in various types of cancer and is associated with poor patient prognoses. CELF2 can directly bind mRNA to a variety of ferroptosis control factors; however,...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Jiahao Li Lei Xian Zifeng Zhu Yang Wang Wenlei Zhang Ruipeng Zheng Wang Xue Jiarui Li Source Type: research
Corrigendum Carvacrol may alleviate vascular inflammation in diabetic db/db mice
Int J Mol Med. 2023 Oct;52(4):90. doi: 10.3892/ijmm.2023.5293. Epub 2023 Aug 18.ABSTRACTFollowing the publication of the above article, the authors contacted the Editorial Office to explain that they made a couple of inadvertent errors in the assembly of the data panels showing the results of immunohistochemical experiments in Fig. 5K on p. 983 (the 'TLR4' experiments); essentially, the data panels selected for the '10 mg/mg Carvacrol' and '5 mg/kg Carvacrol' experiments were copied across from those shown for the 'NF‑κB' experiments in the row above (Fig. 5I). The revised version of Fig. 5, showing the correct data for...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Wei Zhao Chunyan Deng Qizhen Han Hansong Xu Yonghua Chen Source Type: research
< em > Toxoplasma gondii < /em > excretory/secretory proteins promotes osteogenic differentiation of bone marrow mesenchymal stem cells via aerobic glycolysis mediated by Wnt/ β‑catenin signaling pathway
In conclusion, the present study uncovered the potential mechanism by which TgESPs regulate BMSCs, which will provide a theoretical reference for the study of the function of TgESPs in the future.PMID:37594122 | DOI:10.3892/ijmm.2023.5294
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Weiqiang Zhan Juanhua Quan Zhuming Chen Tianfeng Liu Mingzhu Deng Ziquan Zhao Xuyang Wu Zhuolan Zhong Feifei Gao Jiaqi Chu Source Type: research
Predictive value of the sFlt ‑1/PlGF ratio in women with suspected preeclampsia: An update (Review)
Int J Mol Med. 2023 Oct;52(4):89. doi: 10.3892/ijmm.2023.5292. Epub 2023 Aug 18.ABSTRACTPreeclampsia (PE) is a major complication of pregnancy with an incidence rate of 2‑8% and is a leading cause of maternal mortality and morbidity. The various consequences of severe preeclampsia for the fetus, neonate and child include intrauterine growth retardation (IUGR), fetal hypoxia, oligohydramnios, intrauterine fetal demise, increased perinatal mortality and morbidity, neurodevelopmental disorders and even irreversible brain damage (cerebral palsy). A number of studies have demonstrated that differences in maternal serum concen...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Alexandros Velegrakis Elisavet Kouvidi Persefoni Fragkiadaki Stavros Sifakis Source Type: research
Retracted Inhibition airway remodeling and transforming growth factor ‑β1/Smad signaling pathway by astragalus extract in asthmatic mice
Int J Mol Med. 2023 Oct;52(4):87. doi: 10.3892/ijmm.2023.5290. Epub 2023 Aug 18.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the P‑smad2 western blotting data shown in Fig. 7 were strikingly similar to data appearing in different form (namely, the bands appeared in the reverse orientation) in Fig. 4A in another article [Lv Z‑D, Na D, Liu F‑N, Du Z‑M, Sun Z, Li Z, Ma X‑Y, Wang Z‑N and Xu H‑M: Induction of gastric cancer cell adhesion through transforming growth factor‑beta1‑mediated peritoneal fibrosis. J Exp Clin Cancer Res 29: 139, 201...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Zheng-Hai Qu Zhao-Chuan Yang Lei Chen Zhi-Dong Lv Ming-Ji Yi Ni Ran Source Type: research
Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review)
Int J Mol Med. 2023 Oct;52(4):88. doi: 10.3892/ijmm.2023.5291. Epub 2023 Aug 18.ABSTRACTFerroptosis is a novel form of regulated cellular necrosis that plays a critical role in promoting cancer progression and developing drug resistance. The main characteristic of ferroptosis is iron‑dependent lipid peroxidation caused by excess intracellular levels of reactive oxygen species. CUGBP ELAV‑like family number 2 (CELF2) is an RNA‑binding protein that is downregulated in various types of cancer and is associated with poor patient prognoses. CELF2 can directly bind mRNA to a variety of ferroptosis control factors; however,...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Jiahao Li Lei Xian Zifeng Zhu Yang Wang Wenlei Zhang Ruipeng Zheng Wang Xue Jiarui Li Source Type: research
Corrigendum Carvacrol may alleviate vascular inflammation in diabetic db/db mice
Int J Mol Med. 2023 Oct;52(4):90. doi: 10.3892/ijmm.2023.5293. Epub 2023 Aug 18.ABSTRACTFollowing the publication of the above article, the authors contacted the Editorial Office to explain that they made a couple of inadvertent errors in the assembly of the data panels showing the results of immunohistochemical experiments in Fig. 5K on p. 983 (the 'TLR4' experiments); essentially, the data panels selected for the '10 mg/mg Carvacrol' and '5 mg/kg Carvacrol' experiments were copied across from those shown for the 'NF‑κB' experiments in the row above (Fig. 5I). The revised version of Fig. 5, showing the correct data for...
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Wei Zhao Chunyan Deng Qizhen Han Hansong Xu Yonghua Chen Source Type: research
< em > Toxoplasma gondii < /em > excretory/secretory proteins promotes osteogenic differentiation of bone marrow mesenchymal stem cells via aerobic glycolysis mediated by Wnt/ β‑catenin signaling pathway
In conclusion, the present study uncovered the potential mechanism by which TgESPs regulate BMSCs, which will provide a theoretical reference for the study of the function of TgESPs in the future.PMID:37594122 | DOI:10.3892/ijmm.2023.5294
Source: International Journal of Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Weiqiang Zhan Juanhua Quan Zhuming Chen Tianfeng Liu Mingzhu Deng Ziquan Zhao Xuyang Wu Zhuolan Zhong Feifei Gao Jiaqi Chu Source Type: research
