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Advanced imaging in acute ischemic stroke.
Abstract The evaluation and management of acute ischemic stroke has primarily relied on the use of conventional CT and MRI techniques as well as lumen imaging sequences such as CT angiography (CTA) and MR angiography (MRA). Several newer or less-established imaging modalities, including vessel wall MRI, transcranial Doppler ultrasonography, and 4D CTA and MRA, are being developed to complement conventional CT and MRI techniques. Vessel wall MRI provides high-resolution analysis of both extracranial and intracranial vasculature to help identify previously occult lesions or characteristics of lesions that may porten...
Source: Neurosurgical Focus - April 1, 2017 Category: Neurosurgery Authors: Kilburg C, Scott McNally J, de Havenon A, Taussky P, Kalani MY, Park MS Tags: Neurosurg Focus Source Type: research

Magnetic resonance-guided, high-intensity focused ultrasound sonolysis: potential applications for stroke.
Abstract Stroke is one of the leading causes of death worldwide and a significant source of long-term morbidity. Unfortunately, a substantial number of stroke patients either are ineligible or do not significantly benefit from contemporary medical and interventional therapies. To address this void, investigators recently made technological advances to render transcranial MR-guided, high-intensity focused ultrasound (MRg-HIFU) sonolysis a potential therapeutic option for both acute ischemic stroke (AIS)-as an alternative for patients with emergent large-vessel occlusion (ELVO) who are ineligible for endovascular me...
Source: Neurosurgical Focus - February 1, 2018 Category: Neurosurgery Authors: Ilyas A, Chen CJ, Ding D, Romeo A, Buell TJ, Wang TR, Kalani MYS, Park MS Tags: Neurosurg Focus Source Type: research

Automated prediction of final infarct volume in patients with large-vessel occlusion acute ischemic stroke
CONCLUSIONS: In a cohort of patients with LVO AIS in whom reperfusion was achieved, determinations of infarct core at presentation by NCHCT-ASPECTS and a machine learning model analyzing CTA source images were equivalent to CTP in predicting FIV. These findings have suggested that the information to accurately predict infarct core in patients with LVO AIS was present in conventional imaging modalities (NCHCT and CTA) and accessible by machine learning methods.PMID:34198252 | DOI:10.3171/2021.4.FOCUS21134
Source: Neurosurgical Focus - July 1, 2021 Category: Neurosurgery Authors: Rania Abdelkhaleq Youngran Kim Swapnil Khose Peter Kan Sergio Salazar-Marioni Luca Giancardo Sunil A Sheth Source Type: research

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