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Source: Neurosurgical Focus

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Total 545 results found since Jan 2013.

Automated prediction of final infarct volume in patients with large-vessel occlusion acute ischemic stroke
CONCLUSIONS: In a cohort of patients with LVO AIS in whom reperfusion was achieved, determinations of infarct core at presentation by NCHCT-ASPECTS and a machine learning model analyzing CTA source images were equivalent to CTP in predicting FIV. These findings have suggested that the information to accurately predict infarct core in patients with LVO AIS was present in conventional imaging modalities (NCHCT and CTA) and accessible by machine learning methods.PMID:34198252 | DOI:10.3171/2021.4.FOCUS21134
Source: Neurosurgical Focus - July 1, 2021 Category: Neurosurgery Authors: Rania Abdelkhaleq Youngran Kim Swapnil Khose Peter Kan Sergio Salazar-Marioni Luca Giancardo Sunil A Sheth Source Type: research

Editorial: Workforce needs for endovascular acute ischemic stroke therapy: myth or reality?
Abstract The acute ischemic strokes amenable to intraarterial therapy probably number no more than 20,000 per year in the United States. The future demand for intraarterial reperfusion techniques may change, but the fraction of patients who require intraarterial thrombolysis is currently rather low, and the number of neurointerventionists is adequate. Each hospital caring for patients with acute stroke will need to determine its own demand for intraarterial therapy and employ an adequate supply of qualified neurointerventionists available to meet demand. Comprehensive stroke centers are now being designated and ho...
Source: Neurosurgical Focus - January 1, 2014 Category: Neurosurgery Authors: Cloft H Tags: Neurosurg Focus Source Type: research

Antithrombotic selection and risk factor management in ischemic stroke and transient ischemic attack.
Abstract In addition to appropriate antithrombotic therapy, the identification and treatment of modifiable ischemic stroke risk factors can reduce the likelihood of recurrent stroke. Neurosurgeons should be knowledgeable of the specific risk factors and general recommendations for ischemic stroke, as they may play a significant role in the management options for patients with intracranial and extracranial atherosclerotic disease. The authors of this article review the indications for and selection of antithrombotics in patients with cerebral ischemia. In addition, the identification and secondary prevention of sel...
Source: Neurosurgical Focus - January 1, 2014 Category: Neurosurgery Authors: Katz BS, Flemming KD Tags: Neurosurg Focus Source Type: research

Vessel wall signal enhancement on 3-T MRI in acute stroke patients after stent retriever thrombectomy.
CONCLUSIONS The study findings suggest that VW injury incurred during stent retriever thrombectomy can be reliably detected utilizing contrast-enhanced 3-T VW-MRI. The results further demonstrate that endothelial injury is associated with oversizing of stent retrievers relative to the treated vessel. Further studies are needed to evaluate the clinical significance of endothelial injury and to characterize the differential effects of various devices. PMID: 28366071 [PubMed - in process]
Source: Neurosurgical Focus - April 1, 2017 Category: Neurosurgery Authors: Abraham P, Scott Pannell J, Santiago-Dieppa DR, Cheung V, Steinberg J, Wali A, Gupta M, Rennert RC, Lee RR, Khalessi AA Tags: Neurosurg Focus Source Type: research

Experimental neuroprotection in ischemic stroke: a concise review.
Abstract Acute ischemic stroke (AIS) is a leading cause of disability and death worldwide. To date, intravenous tissue plasminogen activator and mechanical thrombectomy have been standards of care for AIS. There have been many advances in diagnostic imaging and endovascular devices for AIS; however, most neuroprotective therapies seem to remain largely in the preclinical phase. While many neuroprotective therapies have been identified in experimental models, none are currently used routinely to treat stroke patients. This review seeks to summarize clinical studies pertaining to neuroprotection, as well as the diff...
Source: Neurosurgical Focus - April 1, 2017 Category: Neurosurgery Authors: Rajah GB, Ding Y Tags: Neurosurg Focus Source Type: research

Revascularization of tandem occlusions in acute ischemic stroke: review of the literature and illustrative case.
CONCLUSIONS In stroke patients with tandem occlusions, distal to proximal revascularization represents a reasonable treatment approach and may offer the advantage of decreased time to reperfusion, which is associated with better functional outcome. Further studies are warranted to determine the best techniques in endovascular therapy to use in this subset of patients in order to improve clinical outcome. PMID: 28366063 [PubMed - in process]
Source: Neurosurgical Focus - April 1, 2017 Category: Neurosurgery Authors: Mbabuike N, Gassie K, Brown B, Miller DA, Tawk RG Tags: Neurosurg Focus Source Type: research

The role of imaging in acute ischemic stroke.
The objectives of imaging include prompt accurate diagnosis, treatment triage, prognosis prediction, and secondary preventative precautions. While capitalizing on the latest treatment options and expanding upon the "time is brain" doctrine, the ultimate goal of imaging is to maximize the number of treated patients and improve the outcome of one the most costly and morbid disease. A broad overview of comprehensive multimodal stroke imaging is presented here to affirm its utilization. PMID: 24380480 [PubMed - in process]
Source: Neurosurgical Focus - January 1, 2014 Category: Neurosurgery Authors: Tong E, Hou Q, Fiebach JB, Wintermark M Tags: Neurosurg Focus Source Type: research