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Stem Cell-Based Tissue Replacement After Stroke: Factual Necessity or Notorious Fiction? Topical Reviews
Source: Stroke - July 27, 2015 Category: Neurology Authors: Janowski, M., Wagner, D.-C., Boltze, J. Tags: Cerebrovascular disease/stroke, Cell biology/structural biology, Acute Cerebral Infarction, Neuroprotectors, Other Stroke Treatment - Medical Topical Reviews Source Type: research

MicroRNA cluster miR-17-92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats Basic Sciences
Conclusions—Our data suggest that treatment of stroke with tailored exosomes enriched with the miR-17–92 cluster increases neural plasticity and functional recovery after stroke, possibly via targeting phosphatase and tensin homolog to activate the PI3K/protein kinase B/mechanistic target of rapamycin/glycogen synthase kinase 3β signaling pathway.
Source: Stroke - February 26, 2017 Category: Neurology Authors: Hongqi Xin, Mark Katakowski, Fengjie Wang, Jian-Yong Qian, Xian Shuang Liu, Meser M. Ali, Benjamin Buller, Zheng Gang Zhang, Michael Chopp Tags: Animal Models of Human Disease, Cell Signaling/Signal Transduction, Cell Therapy, Stem Cells, Translational Studies Original Contributions Source Type: research

Intra-arterial Cell Transplantation Provides Timing-Dependent Cell Distribution and Functional Recovery After Stroke Clinical Sciences
Conclusions— Our results indicate that intra-arterial cell transplantation provides timing-dependent cell distribution and poststroke functional recovery via a combination of neuroprotection, reactive astrocyte enhancement, and angiogenesis.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Ishizaka, S., Horie, N., Satoh, K., Fukuda, Y., Nishida, N., Nagata, I. Tags: Animal models of human disease Clinical Sciences Source Type: research

Stem Cells as an Emerging Paradigm in Stroke 3: Enhancing the Development of Clinical Trials Special Report
Source: Stroke - January 27, 2014 Category: Neurology Authors: Savitz, S. I., Cramer, S. C., Wechsler, L., on behalf of STEPS 3 Consortium, STEPS 3 Consortium:, Aronowski, Boltze, Borlongan, Case, Chase, Chopp, Carmichael, Cramer, Duncan, Finklestein, Fischkoff, Guzman, Hess, Huang, Hinson, Kautz, Kondziolka, Mays, M Tags: Other Ethics and Policy, Other Stroke Treatment - Medical Special Report Source Type: research

Letter by Clark Regarding Article, “Clinical Outcomes of Transplanted Modified Bone Marrow-Derived Mesenchymal Stem Cells in Stroke: A Phase 1/2a Study” Letter to the Editor
Source: Stroke - November 27, 2016 Category: Neurology Authors: Ian A. Clark Tags: Ischemic Stroke Letters to the Editor Source Type: research

Response by Steinberg et al to Letter Regarding Article, “Clinical Outcomes of Transplanted Modified Bone Marrow-Derived Mesenchymal Stem Cells in Stroke: A Phase 1/2A Study” Letter to the Editor
Source: Stroke - November 27, 2016 Category: Neurology Authors: Gary K. Steinberg, Douglas Kondziolka, Damien Bates, on behalf of the SB623 Stroke Phase 1/2A Study Group Tags: Stem Cells Letters to the Editor Source Type: research

Accelerating Cell Therapy for Stroke in Japan Special Reports
Source: Stroke - March 26, 2018 Category: Neurology Authors: Kiyohiro Houkin, Hideo Shichinohe, Koji Abe, Teruyo Arato, Mari Dezawa, Osamu Honmou, Nobutaka Horie, Yasuo Katayama, Kohsuke Kudo, Satoshi Kuroda, Tomohiro Matsuyama, Ichiro Miyai, Izumi Nagata, Kuniyasu Niizuma, Ken Sakushima, Masanori Sasaki, Norihiro Tags: Cell Therapy, Clinical Studies, Stem Cells, Translational Studies, Ischemic Stroke Special Report Source Type: research

Stem Cell-Based Immunomodulation After Stroke Topical Review
Source: Stroke - May 25, 2018 Category: Neurology Authors: Marieke C.S. Boshuizen, Gary K. Steinberg Tags: Inflammation, Stem Cells, Ischemic Stroke Topical Reviews Source Type: research

Mesenchymal Stem Cells Prevent Hydrocephalus After Severe Intraventricular Hemorrhage Basic Sciences
Conclusions— Intraventricular transplantation of umbilical cord blood-derived mesenchymal stem cells significantly attenuated the posthemorrhagic hydrocephalus and brain injury after IVH. This neuroprotective mechanism appears to be mediated by the anti-inflammatory effects of these cells.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Ahn, S. Y., Chang, Y. S., Sung, D. K., Sung, S. I., Yoo, H. S., Lee, J. H., Oh, W. I., Park, W. S. Tags: Animal models of human disease, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Basic Sciences Source Type: research

Are Stem Cells the Next Generation of Stroke Therapeutics? Focused Updates in Cerebrovascular Disease
Source: Stroke - April 23, 2018 Category: Neurology Authors: Sean I. Savitz Tags: Stem Cells Focused Updates in Cerebrovascular Disease Source Type: research

Customized Brain Cells for Stroke Patients Using Pluripotent Stem Cells Focused Updates in Cerebrovascular Disease
Source: Stroke - April 23, 2018 Category: Neurology Authors: Zaal Kokaia, Irene L. Llorente, S. Thomas Carmichael Tags: Basic Science Research, Cell Therapy, Ischemia, Stem Cells Focused Updates in Cerebrovascular Disease Source Type: research

Human Dental Pulp-Derived Stem Cells Protect Against Hypoxic-Ischemic Brain Injury in Neonatal Mice Brief Reports
Conclusions— SHED transplantation into the HI-injured brain resulted in remarkable neurological and pathophysiological recovery. Our findings indicate that paracrine factors derived from SHED support a neuroprotective microenvironment in the HI brain. SHED graft and SHED-conditioned medium may provide a novel neuroprotective therapy for HI.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Yamagata, M., Yamamoto, A., Kako, E., Kaneko, N., Matsubara, K., Sakai, K., Sawamoto, K., Ueda, M. Tags: Animal models of human disease, Apoptosis Brief Reports Source Type: research

Future of Animal Modeling for Poststroke Tissue Repair Focused Updates in Cerebrovascular Disease
Source: Stroke - April 23, 2018 Category: Neurology Authors: Michel M. Modo, Jukka Jolkkonen, Marietta Zille, Johannes Boltze Tags: Animal Models of Human Disease, Basic Science Research, Cell Therapy, Stem Cells, Translational Studies Focused Updates in Cerebrovascular Disease Source Type: research

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