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Source: Transplant Immunology
Procedure: Transplants
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Total 1498 results found since Jan 2013.
Durable complete response to early immunotherapy discontinuation in a kidney transplant recipient with advanced cutaneous squamous cell carcinoma: A case report and review of literature
CONCLUSION: Organ transplant recipients with complete response to immunotherapy for cutaneous squamous cell carcinoma may continue to respond despite early treatment cessation. This may reduce the risks of late immune-related adverse events and acute graft rejection.PMID:37734447 | DOI:10.1016/j.trim.2023.101932
Source: Transplant Immunology - September 21, 2023 Category: Transplant Surgery Authors: Ziyao Lu Mohammed Afzal Keisuke Shirai Source Type: research
Low-MFI (median fluorescence intensity) pre-transplant DSA (donor specific antibodies) leading to anamnestic antibody mediated rejection in live-related donor kidney transplantation
We present two cases of live-related donor kidney transplants (LDKTs) with low-MFI pre-transplant DSA values who experienced an early acute antibody-mediated rejection (ABMR) as a result of an anamnestic antibody response by DSA against HLA class II antibodies. These results were confirmed by retesting of both pre-transplant and post-transplant archived sera from patients as well as freshly obtained donor cells. Our examples indicate a possible ABMR in patients with low MFI pre-transplant DSA. Reclassification of low vs. high-risk may be appropriate for some patients with low-MFI DSA."PMID:37730185 | DOI:10.1016/j.trim.2023.101931
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Rajni Chauhan Aseem Kumar Tiwari Geet Aggarwal L Gowri Suresh Mohit Kumar Shyam Bihari Bansal Source Type: research
Bioequivalence evaluation and blood concentration estimation of generic and branded tacrolimus in healthy subjects under fasting: A randomized, four-periods, two-sequences, complete repeated, crossover study
CONCLUSION: Generic tacrolimus (Ruibeirong®) is bioequivalent to branded tacrolimus (Astagraf XL®) with tolerable safety, which AUC predictive equations work well and are interchangeable between the two products.PMID:37730184 | DOI:10.1016/j.trim.2023.101933
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Yulin Niu Gongbin Lan Jina Wang Tianzhong Yan Peng Jin Source Type: research
Association between blood transfusion after kidney transplantation and risk for the development of de novo HLA donor-specific antibodies and poor clinical outcomes: A single-center retrospective study
CONCLUSIONS: Our study showed that blood transfusion after transplantation is associated with the occurrence of de novo DSAs increasing an immunological risk for poor clinical outcomes for kidney transplantation recipients.PMID:37730183 | DOI:10.1016/j.trim.2023.101930
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Zhong-Yu Kang Chun Liu Wei Liu Daihong Li Source Type: research
Low-MFI (median fluorescence intensity) pre-transplant DSA (donor specific antibodies) leading to anamnestic antibody mediated rejection in live-related donor kidney transplantation
We present two cases of live-related donor kidney transplants (LDKTs) with low-MFI pre-transplant DSA values who experienced an early acute antibody-mediated rejection (ABMR) as a result of an anamnestic antibody response by DSA against HLA class II antibodies. These results were confirmed by retesting of both pre-transplant and post-transplant archived sera from patients as well as freshly obtained donor cells. Our examples indicate a possible ABMR in patients with low MFI pre-transplant DSA. Reclassification of low vs. high-risk may be appropriate for some patients with low-MFI DSA."PMID:37730185 | DOI:10.1016/j.trim.2023.101931
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Rajni Chauhan Aseem Kumar Tiwari Geet Aggarwal L Gowri Suresh Mohit Kumar Shyam Bihari Bansal Source Type: research
Bioequivalence evaluation and blood concentration estimation of generic and branded tacrolimus in healthy subjects under fasting: A randomized, four-periods, two-sequences, complete repeated, crossover study
CONCLUSION: Generic tacrolimus (Ruibeirong®) is bioequivalent to branded tacrolimus (Astagraf XL®) with tolerable safety, which AUC predictive equations work well and are interchangeable between the two products.PMID:37730184 | DOI:10.1016/j.trim.2023.101933
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Yulin Niu Gongbin Lan Jina Wang Tianzhong Yan Peng Jin Source Type: research
Association between blood transfusion after kidney transplantation and risk for the development of de novo HLA donor-specific antibodies and poor clinical outcomes: A single-center retrospective study
CONCLUSIONS: Our study showed that blood transfusion after transplantation is associated with the occurrence of de novo DSAs increasing an immunological risk for poor clinical outcomes for kidney transplantation recipients.PMID:37730183 | DOI:10.1016/j.trim.2023.101930
Source: Transplant Immunology - September 20, 2023 Category: Transplant Surgery Authors: Zhong-Yu Kang Chun Liu Wei Liu Daihong Li Source Type: research
Identification of biomarkers of renal ischemia-reperfusion injury by bioinformatics analysis and single-cell sequencing analysis combined with in vivo validation
CONCLUSION: cyp1a1 and pdk4 were identified to play important roles in renal IRI. This research provides a new perspective and basis for studying the pathogenesis of renal IRI and developing new treatments.PMID:37704087 | DOI:10.1016/j.trim.2023.101928
Source: Transplant Immunology - September 13, 2023 Category: Transplant Surgery Authors: Qin Zhu Shiqi Ren Zhaoyang Sun Jun Qin Xiaoming Sheng Source Type: research
TNF- α -308A/G SNP association with kidney allograft rejection in Algerian population: A retrospective case-control study
Transpl Immunol. 2023 Sep 6:101927. doi: 10.1016/j.trim.2023.101927. Online ahead of print.ABSTRACTNo consensus has been reached regarding the association between the -308A/G single nucleotide polymorphism (SNP) in the tumor necrosis factor-α gene (TNFA) and kidney allograft rejection (KAR). Our retrospective case-control study aimed to assess the association of the SNP with KAR in Algerian patients who underwent kidney transplantation. The study enrolled 313 Algerian patients: 58 kidney-transplant recipients without rejection events (PWoR); 58 kidney-transplant recipients with at least one rejection event, with or withou...
Source: Transplant Immunology - September 8, 2023 Category: Transplant Surgery Authors: Chebine Asmaa Raache Rachida Djendi Asma Kaci Louiza Chelghoum Souad Belkacemi Leila Benziane Ali Saidani Messaoud Khemri Dalila Me ҫabih Fethi Salhi Nawel Akachouche Malika Mechti Bachira Attal Nabila Touil-Boukoffa Chafia Amroun Ait Belkacem Habiba Source Type: research
The dynamic TR β/IGH CDR3 repertoire features in patients with liver transplantation
CONCLUSION: Based on the above results, we can better understand the dynamic changes of TCβ/IGH CDR3 repertoire in patients during liver transplantation.PMID:37683736 | DOI:10.1016/j.trim.2023.101929
Source: Transplant Immunology - September 8, 2023 Category: Transplant Surgery Authors: Junning Zhang Zhenyu Liu Guangyu Wang Xueli Yang Weiguo Sui Haonan Guo Xianliang Hou Source Type: research
TNF- α -308A/G SNP association with kidney allograft rejection in Algerian population: A retrospective case-control study
Transpl Immunol. 2023 Sep 6:101927. doi: 10.1016/j.trim.2023.101927. Online ahead of print.ABSTRACTNo consensus has been reached regarding the association between the -308A/G single nucleotide polymorphism (SNP) in the tumor necrosis factor-α gene (TNFA) and kidney allograft rejection (KAR). Our retrospective case-control study aimed to assess the association of the SNP with KAR in Algerian patients who underwent kidney transplantation. The study enrolled 313 Algerian patients: 58 kidney-transplant recipients without rejection events (PWoR); 58 kidney-transplant recipients with at least one rejection event, with or withou...
Source: Transplant Immunology - September 8, 2023 Category: Transplant Surgery Authors: Chebine Asmaa Raache Rachida Djendi Asma Kaci Louiza Chelghoum Souad Belkacemi Leila Benziane Ali Saidani Messaoud Khemri Dalila Me ҫabih Fethi Salhi Nawel Akachouche Malika Mechti Bachira Attal Nabila Touil-Boukoffa Chafia Amroun Ait Belkacem Habiba Source Type: research
