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Source: International Journal of Medical Microbiology
Vaccination: Malaria Vaccine
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Total 15 results found since Jan 2013.
Plasmodium falciparum rhoptry neck protein 4 has conserved regions mediating interactions with receptors on human erythrocytes and hepatocyte membrane
Int J Med Microbiol. 2023 Apr 3;313(3):151579. doi: 10.1016/j.ijmm.2023.151579. Online ahead of print.ABSTRACTPlasmodium falciparum-related malaria represents a serious worldwide public health problem due to its high mortality rates. P. falciparum expresses rhoptry neck protein 4 (PfRON4) in merozoite and sporozoite rhoptries, it participates in tight junction-TJ formation via the AMA-1/RON complex and is refractory to complete genetic deletion. Despite this, which PfRON4 key regions interact with host cells remain unknown; such information would be useful for combating falciparum malaria. Thirty-two RON4 conserved region-...
Source: International Journal of Medical Microbiology - April 8, 2023 Category: Microbiology Authors: Fredy A Pulido-Quevedo Gabriela Ar évalo-Pinzón Jeimmy J Casta ñeda-Ramírez Adriana Barreto-Santamar ía Manuel E Patarroyo Manuel A Patarroyo Source Type: research
