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Source: International Journal of Cardiology
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Total 880 results found since Jan 2013.
Tissue plasminogen activator deficiency preserves neurological function and protects against murine acute ischemic stroke
We tested the hypothesis that tissue plasminogen activator (tPA) deficiency protected against acute ischemic stroke (AIS)-induced brain injury.
Source: International Journal of Cardiology - November 23, 2015 Category: Cardiology Authors: Hon-Kan Yip, Chun-Man Yuen, Kuan-Hung Chen, Han-Tan Chai, Sheng-Ying Chung, Meng-Shen Tong, Sheng-Yi Chen, Gour-Shenq Kao, Chih-Hung Chen, Yi-Ling Chen, Tien-Hung Huang, Cheuk-Kwan Sun, Mel S. Lee Source Type: research
Effects of functional genetic variants in PPARδ encoding peroxisome proliferator-activated receptor delta on the risk of ischemic stroke in Chinese Han population
Ischemic stroke (IS), a common neurological disease with a variety of causes which is manifested as atherosclerosis or gradual cholesterol deposition, has become a leading cause of death and a major cause of permanent disability in many developed and developing countries. Chronic low-grade inflammation and activation of the innate immune system are closely involved in the pathogenesis of IS [1–2]. Mounting evidences from in vivo and ex vivo studies showed that inflammatory cytokines markers play a vital role in the development of IS [3].
Source: International Journal of Cardiology - January 11, 2016 Category: Cardiology Authors: Yeqing Tong, Xibao Huang, Zhihong Wang, ShengHong Han, Xuhuan Guan, Liangqiang Lin, Xiaoxia Li, Shuangyi Hou, Lei Wang, Bi Cai, Jiafa Liu, Jin-quan Cheng, Zuxun Lu Tags: Correspondence Source Type: research
Diabetes mellitus and risk of ischemic stroke in patients with heart failure and no atrial fibrillation
The risk of ischemic stroke, systemic thromboembolism, and all-cause death among heart failure patients previously diagnosed with diabetes mellitus is poorly described. We evaluated the risk of these endpoints among heart failure patients without diagnosed atrial fibrillation according to the presence of diabetes mellitus.
Source: International Journal of Cardiology - February 2, 2016 Category: Cardiology Authors: Line Melgaard, Anders Gorst-Rasmussen, Peter Søgaard, Lars Hvilsted Rasmussen, Gregory Y.H. Lip, Torben Bjerregaard Larsen Source Type: research
Role of functional polymorphisms of the IL-10 gene promoter in the risk of ischemic stroke in Chinese Uyghur population: One case-control study
Ischemic stroke (IS), a common multifactor neurological disease with a variety of etiologies affected by a number of genetic mutations and environmental factors, is manifested by atherosclerosis or gradual cholesterol deposition. Chronic low-grade inflammation and activation of the innate immune system are closely involved in the pathogenesis of IS [1–2]. Cross-sectional studies have provided support for the hypothesis that chronic subclinical inflammation may be associated with atherosclerosis and precede the progression of clinically overt IS [3–4].
Source: International Journal of Cardiology - March 1, 2016 Category: Cardiology Authors: Yeqing Tong, Li Cai, Yan-wei Zhang, Liangqiang Lin, Shaochu Liu, Shuangyi Hou, Yang Wu, Shenhong Han, Qing Lu, Jiafa Liu Tags: Letter to the Editor Source Type: research
Prevalence of atrial septal pouch and risk of ischemic stroke
It has been postulated that atrial septal pouch (ASP) may favor the stasis of blood and predispose to thromboembolic complications. We sought to evaluate the prevalence of ASP, and its association with ischemic stroke.
Source: International Journal of Cardiology - March 23, 2016 Category: Cardiology Authors: Jing Ping Sun, Fanxia Meng, Xing Sheng Yang, Alex Pui-wai Lee, Ming Chen, Bo Zhang, Cheuk-man Yu Source Type: research
Association between once- and twice-daily direct oral anticoagulant adherence in nonvalvular atrial fibrillation patients and rates of ischemic stroke
A high degree of adherence to direct oral anticoagulants (DOACs) is essential for reducing the risk of ischemic stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF). This is due to the rapid decline in anticoagulation activity when doses are omitted [1].
Source: International Journal of Cardiology - April 3, 2016 Category: Cardiology Authors: Mark J. Alberts, W. Frank Peacock, Larry E. Fields, Thomas J. Bunz, Elaine Nguyen, Dejan Milentijevic, Jeff R. Schein, Craig I. Coleman Tags: Correspondence Source Type: research
Details on methods and further thoughts on P-wave indices in stroke
We thank Dr. Chhabra for showing interest in our research. Earlier, Dr. Chhabra's group have found an association between interatrial block and embolic stroke, as well as with mesenteric ischemia [1,2]. In their studies, the method of measuring P-waves was manual and of high accuracy, using a magnifying graticule [1,2,5]. They did, however, only consider the longest P-wave duration in any single lead, not all leads simultaneously. In our study, we relied on measurements performed by the ECG device, which is considering all 12 leads simultaneously [3,4].
Source: International Journal of Cardiology - April 12, 2016 Category: Cardiology Authors: Jani Pirinen, Jukka Putaala, Mika Lehto Tags: Correspondence Source Type: research
Angiotensin receptor blockers (ARB) outperform angiotensin-converting enzyme (ACE) inhibitors on ischemic stroke prevention in patients with hypertension and diabetes — A real-world population study in Taiwan
Combination therapy with angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) has been stressed for its comprehensive blocking of the renin-angiotensin-aldosterone system, but the evidence for their respective safety and efficacy, in particular with stroke prevention, is still insufficient in population-based follow-up studies in the real world.
Source: International Journal of Cardiology - April 13, 2016 Category: Cardiology Authors: Pei-Ying Pai, Chih-Hsin Muo, Fung-Chang Sung, Hung-Chi Ho, Yuan-Teh Lee Source Type: research
Stroke incidence in patients with cardiac implantable electronic devices remotely controlled with automatic alerts of atrial fibrillation. A sub-analysis of the HomeGuide Study
Remote Monitoring (RM) of cardiac implantable electronic devices (CIEDs) is recommended in management of Atrial Fibrillation (AF), which is a recognized risk factor for thromboembolism. We tried to elucidate whether stroke incidence observed in a large, remotely monitored population was consistent with the CHA2DS2VASc risk profile.
Source: International Journal of Cardiology - June 13, 2016 Category: Cardiology Authors: Renato Pietro Ricci, Diego Vaccari, Loredana Morichelli, Gabriele Zanotto, Leonardo Calò, Antonio D'Onofrio, Antonio Curnis, Ennio C.L. Pisanò, René Nangah, Marco Brieda, Vittorio Calzolari, Donato Melissano, Nicola Rovai, Alessio Gargaro Source Type: research
Hemorrhagic Transformation of Acute Ischemic Stroke is limited in Hypertensive Patients with Cardiac Hypertrophy
It has been clearly demonstrated that hypertension and one of its main evoked effects, cardiac hypertrophy, are independent risk factors for ischemic stroke. However, the ischemic brain lesions can further be affected by a second wave of injury characterized by hemorrhagic transformation (HT) of the primary ischemic lesion, which significantly aggravates the clinical outcome. So far, the risk factors that could affect such a transition in hypertensive patients are still unclear.
Source: International Journal of Cardiology - June 21, 2016 Category: Cardiology Authors: Alessandro Landolfi, Giulio Selvetella, Daniela Cugino, Giovanni Grillea, Angelo Maffei, Antonella Notte, Giuseppe Lembo, Daniela Carnevale Source Type: research
Inadequate stroke prevention in Korean atrial fibrillation patients in the post-warfarin era
This study aimed to investigate the utilization of anticoagulants since the introduction of DOACs in South Korea.
Source: International Journal of Cardiology - June 24, 2016 Category: Cardiology Authors: Eun Joo Choi, Iyn-Hyang Lee, Nam Kyung Je Source Type: research
Cardiology residents' anticoagulation preferences for stroke prophylaxis in atrial fibrillation patients
Atrial fibrillation (AF) is the most common arrhythmia and carries an increased risk of stroke and mortality [1]. To improve survival and reduce morbidity, there are several international guidelines detailing tools to identify patients requiring treatment and direct best practices for medical, interventional and surgical therapies. Some of the more commonly used guidelines include the European Society of Cardiology's (ESC) 2012 update [2]; the American Heart Association (AHA), American College of Cardiology (ACC) and Heart Rhythm Society's (HRS) 2014 guideline [3]; and the Canadian Cardiovascular Society's (CCS) 2014 guidelines [1].
Source: International Journal of Cardiology - July 29, 2016 Category: Cardiology Authors: Jessica Patzer, Zardasht Oqab, William F. McIntyre, Wilma M. Hopman, Adrian Baranchuk Tags: Correspondence Source Type: research
Evolution of acute ischemic stroke therapy from lysis to thrombectomy: Similar or different to acute myocardial infarction?
Acute ischemic stroke remains a major global cause of death, permanent disability, and dementia. For nearly two decades, intravenous tissue plasminogen activator (tPA) has been the only recommended therapy, albeit administered within the recommended time window (i.e.,
Source: International Journal of Cardiology - July 31, 2016 Category: Cardiology Authors: Islam Y. Elgendy, Ahmed N. Mahmoud, Hend Mansoor, Mohammad K. Mojadidi, Anthony A. Bavry Source Type: research
Hypertension in pregnancy and risk of coronary heart disease and stroke: a prospective study in a large UK cohort
We examined the prospective relation between a history of hypertension during pregnancy and coronary heart disease (CHD) and stroke in middle-aged UK women.Methods: In 1996 –2001, 1.1 million parous women (mean age=56years) without vascular disease at baseline reported their history of hypertension during pregnancy and other factors.
Source: International Journal of Cardiology - July 31, 2016 Category: Cardiology Authors: Dexter Canoy, Benjamin J. Cairns, Angela Balkwill, F. Lucy Wright, Asma Khalil, Valerie Beral, Jane Green, Gillian Reeves, Million Women Study Collaborators Source Type: research
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on prevention of stroke:which one is better?
This study is very interesting. In this letter, we would like to discuss some views about choosing renin-angiotensin-aldosterone system (RAAS) inhibitors in clinical practice.
Source: International Journal of Cardiology - August 7, 2016 Category: Cardiology Authors: Lin Xiao, Haichun Ouyang, Qiwen Su, Yuli Huang Tags: Letter to the editor Source Type: research
