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Specialty: Geriatrics
Source: Experimental Gerontology

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Total 63 results found since Jan 2013.

Renal function in familial longevity: The Leiden Longevity Study.
Abstract Studying renal function in subjects with a familial propensity for longevity may provide insight in (un)known mechanisms that determine the age-related decline in renal function of normal subjects. In the Leiden Longevity Study, middle-aged offspring of non-agenarian siblings and their partners as environmentally matched controls were included. Information was collected on lifestyle, medical history, medication use, and a non-fasting blood sample was drawn. Renal function (estimated glomerular filtration rate, eGFR) was assessed with the Chronic Kidney Disease epidemiology collaboration (CKD-EPI) formula....
Source: Experimental Gerontology - January 2, 2014 Category: Geriatrics Authors: de Goeij MC, Halbesma N, Dekker FW, Wijsman CA, van Heemst D, Maier AB, Mooijaart SP, Slagboom PE, Westendorp RG, de Craen AJ Tags: Exp Gerontol Source Type: research

Proteomic Analysis of Mature Adipocytes from Obese Patients in Relation to Aging.
In conclusion, proteomic analysis of subcutaneous adipose tissue reveals differences in the abundance of proteins in adipocytes isolated from young vs. old individuals. These differentially abundant proteins are involved in the regulation of apoptosis, cellular senescence and inflammatory response. All these are common pathologic events in both obesity and aging. PMID: 23886751 [PubMed - as supplied by publisher]
Source: Experimental Gerontology - July 22, 2013 Category: Geriatrics Authors: Alfadda AA, Benabdelkamel H, Masood A, Moustafa A, Sallam R, Bassas A, Duncan M Tags: Exp Gerontol Source Type: research

IL-6 is a predictive biomarker for stroke associated infection and future mortality in the elderly after an ischemic stroke.
CONCLUSIONS: These data suggest that IL-6 may be a key biomarker for predicting stroke associated infection and mortality in the first two years post stroke. PMID: 23872300 [PubMed - as supplied by publisher]
Source: Experimental Gerontology - July 16, 2013 Category: Geriatrics Authors: Kwan J, Horsfield G, Bryant T, Gawne-Cain M, Durward G, Byrne CD, Englyst NA Tags: Exp Gerontol Source Type: research