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Coronary Artery Bypass Grafting Versus Drug-Eluting Stents Implantation for Prior Myocardial Infarction
Patients with prior myocardial infarction (MI) have a high risk of recurrence. Little is known about the effectiveness of coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) with drug-eluting stents (DES) in patients with a prior MI and left main or multivessel coronary artery disease (CAD). We compared long-term outcomes of these two strategies in 672 patients with prior MI and left main or multivessel CAD, who underwent CABG (n=349) or PCI with DES (n=323). A pooled database from the BEST, PRECOMBAT, and SYNTAX trials was analyzed, and the primary outcome was a composite of death from a...
Source: The American Journal of Cardiology - April 19, 2016 Category: Cardiology Authors: Mineok Chang, Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Yaping Zeng, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W. Serruys, Seung-Jung Park Source Type: research

Usefulness of the CHA2DS2-VASC Score to Predict Adverse Outcomes in Patients Having Percutaneous Coronary Intervention
The application of the CHA2DS2-VASC score as a novel risk stratification tool for predicting outcome in clinical applications other than atrial fibrillation and stroke prevention has been previously examined. However, its usefulness in a population of patients with coronary artery disease after percutaneous coronary intervention (PCI) has not been explored. We investigated 12,785 consecutive patients who underwent PCI in a tertiary medical center from April 2004 to August 2014 (mean follow-up 6.5 years) and computed the CHA2DS2-VASC score on their index PCI.
Source: The American Journal of Cardiology - February 16, 2016 Category: Cardiology Authors: Katia Orvin, Tamir Bental, Abid Assali, Eli Israel Lev, Hana Vaknin-Assa, Ran Kornowski Tags: Coronary Artery Disease Source Type: research

Usefulness of the CHA2DS2VASC Score to Predict Adverse Outcomes in Patients having Percutaneous Coronary Intervention
The application of the CHA2DS2-VASC score as a novel risk stratification tool for predicting outcome in clinical applications other than atrial fibrillation (AF) and stroke prevention has been previously examined. However its usefulness in a population of patients with coronary artery disease following percutaneous coronary intervention (PCI) has not been explored. We investigated 12,785 consecutive patients who underwent PCI in a tertiary medical center between 4/2004 and 8/2014 (mean follow up 6.5 years) and computed the CHA2DS2-VASC score on their index PCI.
Source: The American Journal of Cardiology - February 16, 2016 Category: Cardiology Authors: Katia Orvin, Tamir Bental, Abid Assali, Eli Israel Lev, Hana Vaknin-Assa, Ran Kornowski Source Type: research

Usefulness of the CHADSVAS Score to Predict Adverse Outcomes in Patients having Percutaneous Coronary Intervention
The application of the CHA2DS2-VASC score as a novel risk stratification tool for predicting outcome in clinical applications other than atrial fibrillation (AF) and stroke prevention has been previously examined. However its usefulness in a population of patients with coronary artery disease following percutaneous coronary intervention (PCI) has not been explored. We investigated 12,785 consecutive patients who underwent PCI in a tertiary medical center between 4/2004 and 8/2014 (mean follow up 6.5 years) and computed the CHA2DS2-VASC score on their index PCI.
Source: The American Journal of Cardiology - February 16, 2016 Category: Cardiology Authors: Katia Orvin, Tamir Bental, Abid Assali, Eli Israel Lev, Hana Vaknin-Assa, Ran Kornowski Source Type: research

Predictive Value of Combining the Ankle-Brachial Index and SYNTAX Score for the Prediction of Outcome after Percutaneous Coronary Intervention (From the SHINANO Registry)
The SYNTAX score is effective in predicting clinical outcome after percutaneous coronary intervention (PCI). However, its prediction ability is low because it reflects only the coronary characterization. We assessed the predictive value of combining the ankle-brachial index (ABI) and SYNTAX score to predict clinical outcomes after PCI. The ABI-SYNTAX score was calculated for 1197 patients recruited from the SHINANO registry, a prospective, observational, multi-center cohort study in Japan. The primary endpoints were major adverse cardiovascular and cerebrovascular events (MACE; all-cause death, myocardial infarction, and s...
Source: The American Journal of Cardiology - November 5, 2015 Category: Cardiology Authors: Yasushi Ueki, Takashi Miura, Yusuke Miyashita, Hirohiko Motoki, Kentaro Shimada, Masanori Kobayashi, Hiroyuki Nakajima, Hikaru Kimura, Hiroshi Akanuma, Eiichiro Mawatari, Toshio Sato, Shoji Hotta, Yuichi Kamiyoshi, Takuya Maruyama, Noboru Watanabe, Takayu Source Type: research

Balancing the Risk of Bleeding and Stroke in Patients with Atrial Fibrillation after Percutaneous Coronary Intervention (from the AVIATOR-registry)
We describe patterns and determinants of antithrombotic prescriptions in this population. The AVIATOR (Antithrombotic strategy Variability In ATrial fibrillation and Obstructive coronary disease Revascularized with PCI) Registry was an international observational study of 859 consecutive patients with AF undergoing PCI between 2009 and 2011.
Source: The American Journal of Cardiology - April 7, 2015 Category: Cardiology Authors: Marco G. Mennuni, Jonathan L. Halperin, Sameer Bansilal, Mikkel M. Schoos, Kleanthis N. Theodoropoulos, Omar A. Meelu, Samantha Sartori, Daniele Giacoppo, Chiara Bernelli, Pedro R. Moreno, Prakash Krishnan, Usman Baber, Carla Lucarelli, George D. Dangas, Source Type: research

Balancing the Risk of Bleeding and Stroke in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention (from the AVIATOR Registry)
We describe patterns and determinants of antithrombotic prescriptions in this population. The Antithrombotic Strategy Variability in Atrial Fibrillation and Obstructive Coronary Disease Revascularized with PCI Registry was an international observational study of 859 consecutive patients with AF who underwent PCI from 2009 to 2011.
Source: The American Journal of Cardiology - April 7, 2015 Category: Cardiology Authors: Marco G. Mennuni, Jonathan L. Halperin, Sameer Bansilal, Mikkel M. Schoos, Kleanthis N. Theodoropoulos, Omar A. Meelu, Samantha Sartori, Daniele Giacoppo, Chiara Bernelli, Pedro R. Moreno, Prakash Krishnan, Usman Baber, Carla Lucarelli, George D. Dangas, Tags: Coronary Artery Disease Source Type: research

Comparison of Five-Year Outcome of Percutaneous Coronary Intervention With Coronary Artery Bypass Grafting in Triple-Vessel Coronary Artery Disease (from the Coronary Revascularization Demonstrating Outcome Study in Kyoto PCI/CABG Registry Cohort-2)
Studies evaluating long-term (≥5 years) outcomes of percutaneous coronary intervention (PCI) using drug-eluting stents compared with coronary artery bypass grafting (CABG) in patients with triple-vessel coronary artery disease (TVD) are still limited. We identified 2,978 patients with TVD (PCI: n = 1,824, CABG: n = 1,154) of 15,939 patients with first coronary revascularization enrolled in the Coronary Revascularization Demonstrating Outcome Study in Kyoto PCI/CABG Registry Cohort-2. The primary outcome measure in the present analysis was a composite of death, myocardial infarction (MI), and stroke.
Source: The American Journal of Cardiology - April 6, 2015 Category: Cardiology Authors: Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Junichi Tazaki, Ryuzo Sakata, Hitoshi Okabayashi, Michiya Hanyu, Mitsuomi Shimamoto, Noboru Nishiwaki, Tatsuhiko Komiya, Takeshi Kimura, the CREDO-Kyoto PCI/ CABG Registry Cohort-2 Inve Tags: Coronary Artery Disease Source Type: research

Comparison of Five-year Outcome of Percutaneous Coronary Intervention to Coronary Artery Bypass Grafting in Triple Vessel Coronary Artery Disease (From CREDO-Kyoto PCI/CABG Registry Cohort-2)
Studies evaluating long-term (>=5-year) outcomes of percutaneous coronary intervention (PCI) using drug-eluting stents compared with coronary artery bypass grafting (CABG) in patients with triple vessel coronary artery disease (TVD) are still limited. We identified 2978 patients with TVD (PCI: N=1824, CABG: N=1154) among 15939 patients with first coronary revascularization enrolled in the CREDO-Kyoto PCI/CABG registry cohort-2. The primary outcome measure in the current analysis was a composite of death, myocardial infarction (MI), and stroke.
Source: The American Journal of Cardiology - April 6, 2015 Category: Cardiology Authors: Hiroki Shiomi, Takeshi Morimoto, Yutaka Furukawa, Yoshihisa Nakagawa, Junichi Tazaki, Ryuzo Sakata, Hitoshi Okabayashi, Michiya Hanyu, Mitsuomi Shimamoto, Noboru Nishiwaki, Tatsuhiko Komiya, Takeshi Kimura, CREDO-Kyoto PCI/ CABG registry cohort-2 investig Source Type: research

Meta-analysis Of Randomized Controlled Trials and Adjusted Observational Results Of Use Of Clopidogrel, Aspirin and Oral Anti-coagulants In Patients Undergoing Percutaneous Coronary Intervention
The optimal antiaggregant therapy after coronary stenting in patients receiving oral anticoagulation (OAC) is currently debated. Medline and Cochrane Library were searched for studies reporting outcomes of patients undergoing PCI and who were on triple therapy (TT)or dual antiplatelet therapy (DAPT) with aspirin and clopidogrel or dual therapy(DT) with OAC and clopidogrel. Major bleeding was the primary end point, while all-cause death, myocardial infarction (MI), stent thrombosis and stroke were secondary ones.
Source: The American Journal of Cardiology - February 11, 2015 Category: Cardiology Authors: Fabrizio D’Ascenzo, Salma Taha, Claudio Moretti, Pierluigi Omedè, Walter Grossomarra, Jonas Persson, Morten Lamberts, Willem Dewilde, Andrea Rubboli, Sergio Fernández, Enrico Cerrato, Ilaria Meynet, Flavia Ballocca, Umberto Barbero, Giorgio Quadri, Fr Source Type: research

Usefulness and Safety of Vorapaxar in Patients With Non–ST-Segment Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention (from the TRACER Trial)
In conclusion, among patients with PCI, the effect of vorapaxar is consistent with the overall TRACER results. Patients who received a BMS underwent shorter courses of clopidogrel therapy and displayed trends toward greater ischemic benefit from vorapaxar and lesser bleeding risk, compared with patients who received a DES.
Source: The American Journal of Cardiology - June 20, 2014 Category: Cardiology Authors: Marco Valgimigli, Pierluigi Tricoci, Zhen Huang, Philip E. Aylward, Paul W. Armstrong, Frans Van de Werf, Sergio Leonardi, Harvey D. White, Petr Widimsky, Robert A. Harrington, Angel Cequier, Edmond Chen, Yuliya Lokhnygina, Lars Wallentin, John Strony, Ke Tags: Coronary Artery Disease Source Type: research

Comparison of 30-Day and 5-Year Outcomes of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients Aged ≤50 Years (the Coronary aRtery diseAse in younG adultS Study)
Data on the outcome of young patients after coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) are scarce. Data on 2,209 consecutive patients aged ≤50 years who underwent CABG or PCI were retrospectively collected from 15 European institutions. PCI and CABG had similar 30-day mortality rates (0.8% vs 1.4%, p = 0.27), late survival (at 5 years, 97.8% vs 94.9%, p = 0.082), and freedom from stroke (at 5 years, 98.0% and 98.0%, p = 0.731). PCI was associated with significantly lower freedom from major adverse cardiac and cerebrovascular events (at 5 years, 73.9% vs 85.0%, p
Source: The American Journal of Cardiology - May 5, 2014 Category: Cardiology Authors: Fausto Biancari, Tomas Gudbjartsson, Jouni Heikkinen, Vesa Anttila, Timo Mäkikallio, Anders Jeppsson, Linda Thimour-Bergström, Carmelo Mignosa, Antonino S. Rubino, Kari Kuttila, Jarmo Gunn, Jan-Ola Wistbacka, Kari Teittinen, Kari Korpilahti, Francesco O Tags: Coronary Artery Disease Source Type: research

Comparison of Hybrid Coronary Revascularization Versus Coronary Artery Bypass Grafting in Patients ≥65 Years With Multivessel Coronary Artery Disease
In this study, patients aged ≥65 years were included who underwent HCR at an academic center from October 2003 to September 2013. These patients were matched 1:4 to similar patients treated with coronary artery bypass grafting (CABG) using a propensity-score matching algorithm. Conditional logistic regression and Cox regression stratified on matched pairs were performed to evaluate the association between HCR and CABG, and 30-day major adverse cardiovascular and cerebrovascular events (a composite of mortality, myocardial infarction, and stroke), periprocedural complications, and 3-year all-cause mortality. Of 715 patien...
Source: The American Journal of Cardiology - May 5, 2014 Category: Cardiology Authors: Ralf E. Harskamp, John D. Puskas, Jan G. Tijssen, Patrick F. Walker, Henry A. Liberman, Renato D. Lopes, Thomas A. Vassiliades, Eric D. Peterson, Michael E. Halkos Tags: Coronary Artery Disease Source Type: research

Anticoagulant and Antiplatelet Therapy in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention
The prevalence, intensity, safety, and efficacy of oral anticoagulation (OAC) in addition to dual antiplatelet therapy (DAPT) in “real-world” patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) have not yet been fully evaluated. In the Coronary REvascularization Demonstrating Outcome Study in Kyoto registry cohort-2, a total of 1,057 patients with AF (8.3%) were identified among 12,716 patients undergoing first PCI. Cumulative 5-year incidence of stroke was higher in patients with AF than in no-AF patients (12.8% vs 5.8%, p
Source: The American Journal of Cardiology - April 25, 2014 Category: Cardiology Authors: Koji Goto, Kentaro Nakai, Satoshi Shizuta, Takeshi Morimoto, Hiroki Shiomi, Masahiro Natsuaki, Mitsuhiko Yahata, Chihiro Ota, Koh Ono, Takeru Makiyama, Yoshihisa Nakagawa, Yutaka Furukawa, Kazushige Kadota, Yoshiki Takatsu, Takashi Tamura, Akinori Takizaw Tags: Arrhythmias and Conduction Disturbances Source Type: research

Performance of Bleeding Risk-Prediction Scores in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention
In conclusion, the performance of ATRIA, HAS-BLED, mOBRI, and REACH scores in predicting bleeding complications in this high-risk patient subset was useless.
Source: The American Journal of Cardiology - April 3, 2014 Category: Cardiology Authors: Tuomas Kiviniemi, Marja Puurunen, Axel Schlitt, Andrea Rubboli, Pasi Karjalainen, Saila Vikman, Matti Niemelä, Heli Lahtela, Gregory Y.H. Lip, K.E. Juhani Airaksinen Tags: Coronary Artery Disease Source Type: research

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