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Source: Atherosclerosis
Infectious Disease: COVID-19
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Total 36 results found since Jan 2013.
Clinical Characteristics of Patients with Acute Ischemic Stroke Previously Vaccinated Against COVID-19
CONCLUSIONS: There are no significant differences in clinical characteristics of stroke in vaccinated compared to unvaccinated patients. We did not find a connection between vaccination and stroke.PMID:35447380 | PMC:PMC8977441 | DOI:10.1016/j.jstrokecerebrovasdis.2022.106483
Source: Atherosclerosis - April 21, 2022 Category: Cardiology Authors: Marija Stamenkovi ć Ljiljana Radmilo Mirjana Jovi ćević Tamara Rabi- Žikić Marija Žarkov Svetlana Ru žička-Kaloci Svetlana Simi ć Aleksandar Stamenkovi ć Jelena Dangi ć Goran Knezovi ć Željko Živanović Source Type: research
Characteristic of Acute Ischemic Stroke Patients Based on TOAST Classification During COVID-19 Pandemic Era: A Single Centre Study
CONCLUSION: Patients with and without COVID-19 show varied distributions of stroke subtypes according to the TOAST categorization. Hypercoagulation is a major risk factor for stroke of undetermined etiology in individuals with COVID-19 who suffer from acute ischemic stroke. Increased viral-mediated endothelial inflammation leading to aberrant coagulopathy may explain the correlation between COVID-19 and acute ischemic stroke.PMID:36824987 | PMC:PMC9942495 | DOI:10.2147/IJGM.S394017
Source: Atherosclerosis - February 24, 2023 Category: Cardiology Authors: Lisda Amalia Source Type: research
Immune Pathways in Etiology, Acute Phase, and Chronic Sequelae of Ischemic Stroke
Circ Res. 2022 Apr 15;130(8):1167-1186. doi: 10.1161/CIRCRESAHA.121.319994. Epub 2022 Apr 14.ABSTRACTInflammation and immune mechanisms are crucially involved in the pathophysiology of the development, acute damage cascades, and chronic course after ischemic stroke. Atherosclerosis is an inflammatory disease, and, in addition to classical risk factors, maladaptive immune mechanisms lead to an increased risk of stroke. Accordingly, individuals with signs of inflammation or corresponding biomarkers have an increased risk of stroke. Anti-inflammatory drugs, such as IL (interleukin)-1β blockers, methotrexate, or colchicine, r...
Source: Atherosclerosis - April 14, 2022 Category: Cardiology Authors: Matthias Endres Maria A Moro Christian H Nolte Claudia Dames Marion S Buckwalter Andreas Meisel Source Type: research
Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.PMID:36695182 | DOI:10.1161/CIR.0000000000001123
Source: Atherosclerosis - January 25, 2023 Category: Cardiology Authors: Connie W Tsao Aaron W Aday Zaid I Almarzooq Cheryl A M Anderson Pankaj Arora Christy L Avery Carissa M Baker-Smith Andrea Z Beaton Amelia K Boehme Alfred E Buxton Yvonne Commodore-Mensah Mitchell S V Elkind Kelly R Evenson Chete Eze-Nliam Setri Fugar Giul Source Type: research
Integrated head and neck imaging of symptomatic patients with stroke using simultaneous non-contrast cardiovascular magnetic resonance angiography and intraplaque hemorrhage imaging as compared with digital subtraction angiography
CONCLUSIONS: CMR SNAP is consistent with DSA in measuring vessel diameters and identifying atherosclerosis stenosis in each intracranial and carotid vessel segment. SNAP is also a potential alternative to HR-VWI in identifying stenosis and IPH.PMID:35307027 | DOI:10.1186/s12968-022-00849-1
Source: Atherosclerosis - March 21, 2022 Category: Cardiology Authors: Yuxi Jia Xiaoming Liu Lan Zhang Xiangchuang Kong Shuo Chen Lei Zhang Jiazheng Wang Shenglei Shu Jia Liu Xiaona Fu Dingxi Liu Jing Wang Heshui Shi Source Type: research
COVID-19 induced ischemic stroke and mechanisms of viral entry in brain and clot formation: a systematic review and current update
Conclusion: Data available in the literature is not adequate to come to a conclusion. Therefore, there is a need to carry out further studies to delineate the possible association between SCV-2 induced IS.PMID:35412938 | DOI:10.1080/00207454.2022.2056460
Source: Atherosclerosis - April 12, 2022 Category: Cardiology Authors: Abhilash Ludhiadch Swaraj Ranjan Paul Rahul Khan Anjana Munshi Source Type: research
Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes
Int J Mol Sci. 2023 Aug 30;24(17):13452. doi: 10.3390/ijms241713452.ABSTRACTWe aimed to analyse whether patients with ischaemic stroke (IS) occurring within eight days after the onset of COVID-19 (IS-COV) are associated with a specific aetiology of IS. We used SUPERGNOVA to identify genome regions that correlate between the IS-COV cohort (73 IS-COV cases vs. 701 population controls) and different aetiological subtypes. Polygenic risk scores (PRSs) for each subtype were generated and tested in the IS-COV cohort using PRSice-2 and PLINK to find genetic associations. Both analyses used the IS-COV cohort and GWAS from MEGASTRO...
Source: Atherosclerosis - September 9, 2023 Category: Cardiology Authors: Laia Lluci à-Carol Elena Mui ño Natalia Cullell Jara C árcel-Márquez Miquel Lled ós Cristina Gallego-Fabrega Jes ús Martin-Campos Joan Mart í-Fàbregas Ana Aguilera-Sim ón Anna M Planas Marta L DeDiego Alicia de Felipe Mimbrera Jaime Masjuan Sebas Source Type: research
Carotid free-floating thrombus in COVID-19: a cerebrovascular disorder of cytokine storm-related immunothrombosis
CONCLUSIONS: COVID-19-induced immunothrombosis possibly played a significant pathogenic role in CFFT.PMID:36807242 | DOI:10.1007/s10072-023-06682-3
Source: Atherosclerosis - February 22, 2023 Category: Cardiology Authors: Umberto Pensato Stefano Forlivesi Mauro Gentile Michele Romoli Lorenzo Muccioli Francesca Ambrosi Maria Pia Foschini Carmine Gallo Maria Sandra Ballestrazzi Paolo Teutonico Gianluca Faggioli Mauro Gargiulo Simone Galluzzo Francesco Taglialatela Luigi Simo Source Type: research
Unexplained arterial thrombosis: approach to diagnosis and treatment
We present a structured approach to diagnosis with consideration of common causes, including atherosclerosis and embolism, as well as uncommon causes, including medications and substances, vascular and anatomic abnormalities, systemic disorders, and thrombophilias. We highlight areas of management that have evolved within the past 5 years, including the use of dual-pathway inhibition in atherosclerotic disease, antithrombotic therapy selection in embolic stroke of undetermined source and left ventricular thrombus, the role of closure of patent foramen ovale for secondary stroke prevention, and the thrombotic potential of c...
Source: Atherosclerosis - December 10, 2021 Category: Cardiology Authors: Jori E May Stephan Moll Source Type: research
Bioinformatics analysis of potential therapeutic targets for COVID-19 infection in patients with carotid atherosclerosis
CONCLUSIONS: With COVID-19 being a relatively new disease, associations have been proposed for its connections with several ailments and conditions, including IS and carotid atherosclerosis. More patient-based data-sets and studies are needed to fully explore and understand the relationship.PMID:35344771 | DOI:10.1016/j.jiph.2022.03.004
Source: Atherosclerosis - March 28, 2022 Category: Cardiology Authors: Liang Yanchao Zhang Sibin Ilgiz Gareev Xiang Huan Zhao Junfei Liu Chunyang Ozal Beylerli Albert Sufianov Yuan Chao Gai Yuyan Xu Xun Aamir Ahmad Liang Peng Yang Guang Source Type: research
Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: Atherosclerosis - October 6, 2022 Category: Cardiology Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research
Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation
Front Nutr. 2022 Nov 1;9:1007816. doi: 10.3389/fnut.2022.1007816. eCollection 2022.ABSTRACTMany local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation. The GSH tripeptide (γ- L-glutamyl-L-cysteinyl-glycine), the most abundant w...
Source: Atherosclerosis - November 17, 2022 Category: Cardiology Authors: Carlos A Labarrere Ghassan S Kassab Source Type: research
