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Source: European Neurology

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Total 178 results found since Jan 2013.

Post Stroke Dysglycemia and Acute Infarct Volume Growth: A Study Using Continuous Glucose Monitoring
Background: The aim of the present study was to clarify the effect of glucose profiles after stroke, which was assessed by a continuous glucose monitoring (CGM) device.Methods: Acute ischemic stroke patients within 24 h of onset were prospectively studied. CGM was performed for 72 h after admission. CGM parameters were evaluated as follows: (1) mean glucose level, (2) area under the curve (AUC) for glucose level>140 mg/dl and (3) SD of the glucose level. Infarct volume was measured at admission and 24 and 72 h after admission using diffusion-weighted imaging. CGM data and infarct volume growth were compared at 24 and 72 h....
Source: European Neurology - September 19, 2016 Category: Neurology Source Type: research

Potentially Serious Drug-Drug Interactions in Older Patients Hospitalized for Acute Ischemic and Hemorrhagic Stroke
Background: Polypharmacy is very common in older persons and it is associated with inappropriate prescribing and potential drug-drug interactions (DDIs). Aims of this study were to identify prevalence of DDIs in older persons with acute stroke and to evaluate the association between stroke and DDIs.Methods: One hundred forty-six patients admitted with diagnosis of acute stroke were enrolled. The therapeutic regimen of patients was analyzed at admission to identify the number of DDIs, prevalence and sorts of serious DDIs according to subtype of acute stroke (ischemic or hemorrhagic) and to its recurrence.Results: Five hundr...
Source: European Neurology - September 9, 2016 Category: Neurology Source Type: research

The Effect of Passive Movement for Paretic Ankle-Foot and Brain Activity in Post-Stroke Patients
Conclusion: Manual therapy with CPM device therapy improved the ankle PROM, equinovalgus and severity of spasticity. The ankle PM increased ipsi- and contralateral cortical activation.Eur Neurol 2016;76:132-142
Source: European Neurology - August 30, 2016 Category: Neurology Source Type: research

Associations between Thyroid Stimulating Hormone Levels and Both Severity and Early Outcome of Patients with Ischemic Stroke
We aimed to investigate associations between serum thyroid stimulating hormone (TSH) levels and both severity and outcome after ischemic stroke (IS). A total of 731 patients consecutive IS patients were enrolled (mean age 69.4 ± 15.4, 61.6% men), and serum TSH levels were measured at admission and analyzed according to the tertiles of their distribution (1.6 mUI/l). Associations between TSH and both severity at admission (National Institutes of Health Stroke Scale (NIHSS) scores
Source: European Neurology - August 26, 2016 Category: Neurology Source Type: research

Severe White Matter Hyperintensity Is Associated with Early Neurological Deterioration in Patients with Isolated Pontine Infarction
Conclusions: Both severe PVWMH and SCWMH were useful to predict END in patients with isolated pontine infarction.Eur Neurol 2016;76:117-122
Source: European Neurology - August 17, 2016 Category: Neurology Source Type: research

Predictive Factors for Excellent or Extremely Poor Functional Outcome in Initial Atrial Fibrillation-Related Cardioembolic Stroke
Conclusions: Predictive factors exist to delineate excellent and extremely poor functional outcomes after a first-time stroke associated with AF.Eur Neurol 2016;76:105-111
Source: European Neurology - August 10, 2016 Category: Neurology Source Type: research

Spinal Cord Infarction in Clinical Neurology: A Review of Characteristics and Long-Term Prognosis in Comparison to Cerebral Infarction
Spinal cord stroke is rare accounting for 0.3-1% of all strokes and is classified into upper (cervical) and lower (thoracolumbar) strokes. Patients present with severe deficits but later often show good functional improvement. On admission, younger age, male gender, hypertension, diabetes mellitus and elevated blood glucose indicate more severe spinal cord strokes. Treatment of these risk factors is essential in the acute phase. Biphasic spinal cord strokes are seen in one-fifth of the patients. These present with acute or transient sensory spinal cord deficits often preceded by radiating pain between the shoulders, and sh...
Source: European Neurology - August 3, 2016 Category: Neurology Source Type: research

Silent Coronary Artery Disease in Symptomatic Candidates for Carotid Revascularization Intervention
Conclusions: About 60% of stroke patients with extracranial CAS have an incident CAD. Hypertension, hyperlipidemia, and the atherosclerotic changes of combined extracranial carotid and intracranial arteries may increase the risk of asymptomatic CAD in symptomatic candidates for carotid revascularization intervention.Eur Neurol 2016;76:69-74
Source: European Neurology - July 7, 2016 Category: Neurology Source Type: research

Decompressive Hemicraniectomy in Malignant Middle Cerebral Artery Infarction: The ‘Real World' Beyond Studies
Conclusions: DHC is a life-saving technique in patients with MMI, but complications are frequent, were underestimated in randomized clinical trials and may worsen the functional outcome.Eur Neurol 2016;76:48-56
Source: European Neurology - July 6, 2016 Category: Neurology Source Type: research

Clinical and Neuroimaging Features of Acute Ischemic Stroke in Cancer Patients
Background: The occurrence of acute ischemic stroke in cancer patients is not unusual. In clinical practice, acute ischemic stroke with cancer usually cannot be diagnosed promptly due to lack of specific markers. But for cancer patients, advanced prevention, accurate diagnosis and proper treatment of acute ischemic stroke are very important. The aim of the present study was to investigate the clinical and neuroimaging features of acute ischemic stroke in patients with cancer. Methods: We conducted a retrospective review of all cancer-associated acute ischemic stroke patients (n = 46) admitted to the Affiliated Hospital of ...
Source: European Neurology - June 14, 2016 Category: Neurology Source Type: research

Susceptibility Vessel Sign in Isolated Brainstem Infarction with Large Artery Occlusion
Conclusions: SVS reflects pathology of deoxidized red cells composition in patients with isolated brainstem infarction. This finding may be useful to explore the different stroke mechanisms and therapy strategies.Eur Neurol 2016;75:251-256
Source: European Neurology - May 12, 2016 Category: Neurology Source Type: research

Autonomic Cardiac Response to Static and Dynamic Muscle Contractions in Post-Stroke and Healthy Subjects
Conclusion: Patients post stroke in the subacute phase have alterations in cardiac rhythm regulation both at rest and during muscle effort. The extent of the cardiac autonomic response to muscle contraction is associated with contraction type and time post event. Simple measurement of HRV in different conditions enables monitoring of recovery of autonomic nervous system cardiac control.Eur Neurol 2016;75:207-212
Source: European Neurology - April 22, 2016 Category: Neurology Source Type: research

Determinants of Basal Collaterals in Moyamoya Disease: Clinical and Genetic Factors
Conclusion: Although prominent BCs are required for diagnosis of MMD, BCs are decreased with aging, suggesting that angiogenic capacity is altered in adult onset MMD compared to childhood MMD.Eur Neurol 2016;75:178-185
Source: European Neurology - April 5, 2016 Category: Neurology Source Type: research

Is It Acute Stroke or Not - A Prospective Observational Study from a Multidisciplinary Emergency Department
Background: Acute stroke is a medical emergency with various clinical presentations. Since the introduction of systemic thrombolytic treatment, stroke diagnosis has been made quickly and with great caution, and the trend of rapid presentation at hospitals has increased. Methods: In our multidisciplinary Emergency Department, we prospectively collected and analysed data of consecutive patients presenting with suspected acute stroke (SAS) or transient ischemic attack (TIA). Results: Four hundred ten patients (200 men, mean age 68 ± 16, range 17-93 years) with SAS were admitted of which 105 were prehospitally announced as wi...
Source: European Neurology - April 1, 2016 Category: Neurology Source Type: research

Is It Acute Stroke or Not? - A Prospective Observational Study from a Multidisciplinary Emergency Department
Background: Acute stroke is a medical emergency with various clinical presentations. Since the introduction of systemic thrombolytic treatment, stroke diagnosis has been made quickly and with great caution, and the trend of rapid presentation at hospitals has increased. Methods: In our multidisciplinary Emergency Department, we prospectively collected and analysed data of consecutive patients presenting with suspected acute stroke (SAS) or transient ischemic attack (TIA). Results: Four hundred ten patients (200 men, mean age 68 ± 16, range 17-93 years) with SAS were admitted of which 105 were prehospitally announced as wi...
Source: European Neurology - March 31, 2016 Category: Neurology Source Type: research