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Specialty: Neurology
Source: Cerebrovascular Diseases
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Total 653 results found since Jan 2013.
Clinical Relevance of Computed Tomography Perfusion-Estimated Infarct Volume in Acute Ischemic Stroke Patients within the 6-h Therapeutic Time Window
Conclusion: Larger initial infarct volumes are significantly associated with worse clinical outcomes in patients who underwent EVT because of early time window stroke. Furthermore, our study of 6-h data demonstrated that an initial infarction of more than a certain volume might be an independent risk factor for sICH development and poor outcomes even in patients with successful recanalization. However, we still observed benefits of EVT in patients with large ischemic cores. The CTP-estimated infarct volume might be an important prognostic factor after EVT rather than a biomarker predicting treatment effectiveness.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 21, 2022 Category: Neurology Source Type: research
Repetitive Transcranial Magnetic Stimulation of the Contralesional Dorsal Premotor Cortex for Upper Extremity Motor Improvement in Severe Stroke: Study Protocol for a Pilot Randomized Clinical Trial
Up to 50% of stroke survivors have persistent, severe upper extremity paresis even after receiving rehabilitation. Repetitive transcranial magnetic stimulation (rTMS) can augment the effects of rehabilitation by modulating corticomotor excitability, but the conventional approach of facilitating excitability of the ipsilesional primary motor cortex (iM1) fails to produce motor improvement in stroke survivors with severe loss of ipsilesional substrate. Instead, the undamaged, contralesional dorsal premotor cortex (cPMd) may be a more suitable target. CPMd can offer alternate, bi-hemispheric and ipsilateral connections in sup...
Source: Cerebrovascular Diseases - January 20, 2022 Category: Neurology Source Type: research
Effects of Dose Titration on Dipyridamole-Induced Headache: A Randomized, Double-Blind Clinical Trial
Conclusion: The titration strategy was effective in lowering the incidence of cumulative dipyridamole-induced headache.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 14, 2022 Category: Neurology Source Type: research
Rural-Urban Differences in Diagnosed Cervical Artery Dissection in New York State
Conclusions: CeAD diagnosis correlates with population density as defined by rural-urban status. Our results could be due to underdiagnosis in rural areas or overdiagnosis with increasing urbanicity.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 14, 2022 Category: Neurology Source Type: research
Neuroimaging Prediction of Hemorrhagic Transformation for Acute Ischemic Stroke
Background: Hemorrhagic transformation (HT) is a common complication of acute ischemic stroke, often resulting from reperfusion therapy. Early prediction of HT can enable stroke neurologists to undertake measures to avoid clinical deterioration and make optimal treatment strategies. Moreover, the trend of extending the time window for reperfusion therapy (both for intravenous thrombolysis and endovascular treatment) further requires more precise detection of HT tendency.Summary: In this review, we summarized and discussed the neuroimaging markers of HT prediction of acute ischemic stroke patients, mainly focusing on neuroi...
Source: Cerebrovascular Diseases - January 13, 2022 Category: Neurology Source Type: research
Do Concentration or Activity of Selenoproteins Change in Acute Stroke Patients? A Systematic Review and Meta-Analyses
Conclusions: Our results suggest a reduction of the blood GPx activity in acute ischaemic stroke patients, a lack of evidence regarding a role for GPx in haemorrhagic stroke patients, and insufficient evidence for other selenoproteins.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 4, 2022 Category: Neurology Source Type: research
ASPECTS-Based Attenuation Changes on CT Angiography as an Imaging Biomarker to Predict Hemorrhagic Transformation in Acute Ischemic Stroke
Conclusion: CTASI-ASPECTS-HU is a reliable radiological predictor of HT and PH in patients with AIS. Its predictive efficacy is moderately improved when combined with NIHSS score.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 4, 2022 Category: Neurology Source Type: research
Normobaric Oxygen Therapy in Acute Stroke: A Systematic Review and Meta-Analysis
Conclusion: Studies of NBO have shown no significant effect on early neurological recovery, functional outcome, or mortality in acute stroke. Oxygen has been predominantly low-flow and commenced in the sub-acute phase.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 4, 2022 Category: Neurology Source Type: research
People with Stroke Are Most Sedentary in the Afternoon and Evening
Conclusion: People living at home after stroke are highly sedentary, particularly in the afternoons and evenings, and this pattern does not change during the first year after stroke. Clinicians should encourage people with stroke to find meaningful tasks to do during the day to reduce their sitting time. Researchers developing interventions to encourage people to sit less should include particular focus on the afternoon and evening time periods.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 4, 2022 Category: Neurology Source Type: research
Risk Factors for General Anesthesia Conversion in Anterior Circulation Stroke Patients Undergoing Endovascular Treatment
Conclusion: In our study, tandem occlusion, longer endovascular procedures, SOFA, and number of pharmacological agents used predicted the risk of emergent conversion to GA in stroke patients undergoing endovascular treatment. Prospective studies investigating optimal CS strategies are deemed necessary.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 29, 2021 Category: Neurology Source Type: research
Exercise-Based Cardiac Rehabilitation Associates with Lower Major Adverse Cardiovascular Events in People with Stroke
Conclusion: Exercise-based cardiac rehabilitation prescribed for people following a stroke associated with significantly lower odds of major adverse cardiovascular events at 2 years, compared to usual care.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 20, 2021 Category: Neurology Source Type: research
Underdosed Direct Oral Anticoagulants in Atrial Fibrillation Patients Reduce Stroke Severity and Improve Outcome
Conclusions: In patients with atrial fibrillation, recommended doses and underdoses of DOACs reduced stroke severity on admission and were associated with good 3-month outcomes.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 20, 2021 Category: Neurology Source Type: research
Are Differences in Dysphagia Assessment, Oral Care Provision, or Nasogastric Tube Insertion Associated with Stroke-Associated Pneumonia? A Nationwide Survey Linked to National Stroke Registry Data
Conclusion: Variation exists in dysphagia screening and management, but there was no evidence of an association between clinical practice patterns and incidence of SAP. Further research with larger sample sizes is needed to examine association with SAP.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 16, 2021 Category: Neurology Source Type: research
Association between Apolipoprotein E Polymorphism and Clinical Outcome after Ischemic Stroke, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage
Conclusions: In conclusion, the present study demonstratedAPOEε4 carriers show worse functional outcomes after ICH, but not after IS or SAH. More large-scale studies were critical to explore the association betweenAPOE polymorphism and clinical outcome after IS, ICH, and SAH.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 15, 2021 Category: Neurology Source Type: research
Association of Multiple Passes during Mechanical Thrombectomy with Incomplete Reperfusion and Lesion Growth
Conclusions: Our findings suggest that incomplete reperfusion on post-EVT MRI is present even in some patients with successful recanalization at the time of EVT and is associated with multiple-pass thrombectomy, lesion growth, and worse outcome. Future studies are needed to investigate whether patients with residual hypoperfusion may benefit from immediate adjunctive therapy to limit lesion growth and improve clinical outcome.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 13, 2021 Category: Neurology Source Type: research
