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Specialty: Neurology
Source: Cerebrovascular Diseases

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Total 653 results found since Jan 2013.

Efficacy and Safety of Vagus Nerve Stimulation in Stroke Rehabilitation: A Systematic Review and Meta-Analysis
Conclusion: VNS may be an effective and safe adjunct to standard rehabilitation for post-stroke recovery; however, its clinical significance and long-term efficacy and safety remain unclear.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 27, 2022 Category: Neurology Source Type: research

circCELF1 Induces the Apoptosis and Autophagy of Astrocytes in Ischemic Stroke via Upregulating NFAT5
Conclusion: circCELF1 recruits DDX54 to upregulate NFAT5, by which astrocyte apoptosis and autophagy are stimulated.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 19, 2022 Category: Neurology Source Type: research

Atrial Tachyarrhythmias and Stroke: Temporal Relationship and Stroke Subtypes
Conclusions: CE strokes were associated with a significantly higher proportion of preceding AT/AF compared with non-CE strokes. These findings support a potential temporal relationship between AT/AF and CE stroke and demonstrate that stroke subtyping can better characterize the relationship between AF and ischemic stroke. However, this study ’s findings are limited by its sample size and small number of informative cases.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 9, 2022 Category: Neurology Source Type: research

Meta-Analysis of the Use of Head Impulse Test and Head Impulse Test with Direction Changing Nystagmus and Test of Skew Deviation in the Diagnosis of Peripheral Vertigo and Stroke
Conclusion: The HIT and HINTS exams appear to be moderately good discriminators of central and PV. However, in most papers, the tests were administered by neurologists and were evaluated beyond 24 h, which may limit utility in the ED setting.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 9, 2022 Category: Neurology Source Type: research

Capsular Warning Syndrome: Features, Risk Profile, and Prognosis in a Large Prospective TIA Cohort
Conclusions: CWS is associated with higher stroke risk and better functional prognosis than L- and NL-TIAs. CWS risk profile is consistent with severe small vessel disease, and ND hypertension could represent a major risk factor. DAPT and IVT seem effective and safe in preventing and treating stroke following CWS.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 9, 2022 Category: Neurology Source Type: research

Mortality in a Multiethnic Population Attending a One-Stop TIA Clinic
This study identified possible risk factors associated with a higher mortality in TIA clinic attendees, who may benefit from specific intervention. Future research should explore the underlying causes and the effect of specific targeted management strategies.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 1, 2022 Category: Neurology Source Type: research

Cost-Effectiveness of Low-Dose Compared to Standard-Dose Alteplase for Acute Ischemic Stroke in China: A Within-Trial Economic Evaluation of the ENCHANTED Study
Conclusions: This health economic evaluation alongside the ENCHANTED indicates that the use of low-dose alteplase does not save overall healthcare costs nor lead to a gain in QALYs in the management of Chinese patients with AIS compared to the use of standard dose. There is little justification on economic grounds to shift from standard-of-care thrombolysis in AIS.Cerebrovasc Dis
Source: Cerebrovascular Diseases - August 31, 2022 Category: Neurology Source Type: research

Preventing Recurrent Cardioembolic Stroke: Right Approach, Right Patient (PRECISE) Study Protocol
Cardiac rhythm monitoring is performed to search for atrial fibrillation (AF) after ischaemic stroke or transient ischaemic attack (TIA). Prolonged cardiac rhythm monitoring increases AF detection but is challenging to implement in many healthcare settings and is not needed for all people after ischaemic stroke/TIA. We aimed to develop and validate a model that includes clinical, electrocardiogram (ECG), blood-based, and genetic biomarkers to identify people with a low probability of AF detection after ischaemic stroke or TIA. We will recruit 675 consenting participants who are aged over 18 years, who were admitted with is...
Source: Cerebrovascular Diseases - August 29, 2022 Category: Neurology Source Type: research

Consistencies and Differences in Intermediate Physiological Phenotypes of Vascular Ageing between Ischaemic Stroke Aetiologies
Conclusions: Intermediate cardiovascular phenotypes of vascular ageing had similar demographic associations between stroke aetiologies, but these were particularly strong in patients with small vessel stroke under the age of 65, implying a potential role of these phenotypes in increasing stroke risk in this patient group.Cerebrovasc Dis
Source: Cerebrovascular Diseases - August 23, 2022 Category: Neurology Source Type: research

Control of Diabetes Mellitus and Long-Term Prognosis in Stroke Patients: The Shiga Stroke and Heart Attack Registry
Conclusions: The findings suggest that first-ever stroke patients with diabetes exhibited a higher risk of all-cause mortality than those without diabetes, particularly in the overall stroke and ischemic stroke populations. Additionally, in stroke populations after 28 days of onset, high risk of long-term mortality was stated in stroke patients with poor HbA1c control.Cerebrovasc Dis
Source: Cerebrovascular Diseases - August 3, 2022 Category: Neurology Source Type: research

Total Hemoglobin Mass Correlates with Peak Oxygen Consumption in Patients with Chronic Stroke
Conclusion: Our results suggested that low [Hb] seems to contribute to V.O2peak in stroke patients. The significant correlation between tHb-mass and V.O2peak suggested that treatment to improve [Hb] can potentially improve V.O2peak in stroke patients.Cerebrovasc Dis
Source: Cerebrovascular Diseases - August 2, 2022 Category: Neurology Source Type: research

Association of High-Sensitivity Troponin I with Cardiac and Cerebrovascular Events in Patient after Ischemic Stroke
Conclusions: Elevated hs-TnI is independently associated with higher mortality and cardiac and cerebrovascular events in patients with ischemic stroke and may serve as a valuable prognostic factor in management after ischemic stroke.Cerebrovasc Dis
Source: Cerebrovascular Diseases - July 29, 2022 Category: Neurology Source Type: research

Association between Baseline NIHSS Limb Motor Score and Functional Recovery after Stroke: Analysis Based on a Multicountry Dataset
Conclusions: As an independent association between b-NIHSS-LMS and functional recovery after an acute ischaemic stroke of intermediate severity was established in this study, we suggest that the b-NIHSS-LMS can be used as a stratification factor in large clinical trials to define a target population with poststroke motor impairments.Cerebrovasc Dis
Source: Cerebrovascular Diseases - July 29, 2022 Category: Neurology Source Type: research

Significance of Low Signal in Intracranial Vertebral Artery Wall Observed on Susceptibility-Weighted Angiography
Conclusion: Low signals on susceptibility-weighted angiography were frequently observed in vertebral artery dissection and atherothrombosis, reflecting intramural hematoma in all of the former and predominantly calcification in the latter.Cerebrovasc Dis
Source: Cerebrovascular Diseases - July 6, 2022 Category: Neurology Source Type: research

Association between GNAQ Gene DNA Methylation and Vascular Recurrence in Patients with Acute Ischemic Stroke or Transient Ischemic Attack
Conclusions: Hypomethylation of CpG 32 –39 of GANQ gene was associated with a higher risk of ischemic events for clopidogrel-treated acute ischemic stroke or TIA patients. Further studies were warranted to explain the possible mechanism.Cerebrovasc Dis
Source: Cerebrovascular Diseases - June 28, 2022 Category: Neurology Source Type: research