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Source: Cerebrovascular Diseases
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Total 653 results found since Jan 2013.
Post-Stroke Fatigue May Be Associated with the Promoter Region of a < b > < i > Monoamine Oxidase A < /i > < /b > Gene Polymorphism
Background: Post-stroke fatigue (PSF) is a common sequela of stroke. Despite reports of serotonergic involvement in the etiology of PSF, the potential contribution of serotonergic genes in the development of PSF needs to be investigated.Methods: A total of 373 patients, who experienced ischemic stroke for PSF, were evaluated 3 months after the stroke. PSF was assessed using the Fatigue Severity Scale. The genomic DNA collected and stored in a -70 °C freezer was genotyped for 6 polymorphisms in genes associated with serotonin synthesis (tryptophan hydroxylase 1 (TPH1) A218C, TPH2 rs10879355, and TPH2 rs4641528), transport ...
Source: Cerebrovascular Diseases - November 18, 2016 Category: Neurology Source Type: research
Post-Stroke Fatigue May Be Associated with the Promoter Region of a Monoamine Oxidase A Gene Polymorphism
Background: Post-stroke fatigue (PSF) is a common sequela of stroke. Despite reports of serotonergic involvement in the etiology of PSF, the potential contribution of serotonergic genes in the development of PSF needs to be investigated.Methods: A total of 373 patients, who experienced ischemic stroke for PSF, were evaluated 3 months after the stroke. PSF was assessed using the Fatigue Severity Scale. The genomic DNA collected and stored in a -70 °C freezer was genotyped for 6 polymorphisms in genes associated with serotonin synthesis (tryptophan hydroxylase 1 (TPH1) A218C, TPH2 rs10879355, and TPH2 rs4641528), transport ...
Source: Cerebrovascular Diseases - November 21, 2016 Category: Neurology Source Type: research
Factors Related to Cardioembolism as Major Predictors of Poor Survival after First-Ever Middle Cerebral Artery Stroke Treated with Thrombolysis
Background and Purpose: Prognostic factors related to mortality rates after stroke have been reported; however, most studies included different treatments and did not focus solely on ischemic stroke. The study aimed to report the short- and long-term survival and predictors of death in patients with first-ever ischemic stroke in the middle cerebral artery (MCA) territory, submitted to intravenous thrombolysis (IVT).Methods: A prospective observational cohort study of patients with first-ever ischemic stroke in the MCA territory treated with IVT from March 2010 to February 2015 was conducted, and patients were followed up u...
Source: Cerebrovascular Diseases - February 16, 2017 Category: Neurology Source Type: research
Distal Middle Cerebral Artery Branch Recanalization Does Not Affect Final Lesion Volume in Ischemic Stroke
Conclusions: The high rate of spontaneous recanalization and good functional outcome in patients with distal MCA pathology might obscure a potential benefit from recanalization in this population.Cerebrovasc Dis 2017;43:200-205
Source: Cerebrovascular Diseases - February 16, 2017 Category: Neurology Source Type: research
High Prestroke Physical Activity Is Associated with Reduced Infarct Growth in Acute Ischemic Stroke Patients Treated with Intravenous tPA and Randomized to Remote Ischemic Perconditioning
Conclusion: In AIS patients treated with RIPerC, as add-on to intravenous thrombolysis, the level of PA the week before the stroke was associated with decreased 24-h infarct growth and final infarct size. These results are highly encouraging and stress the need for further exploration of the potentially protective effects of both PA and remote ischemic conditioning.Cerebrovasc Dis 2017;44:88-95
Source: Cerebrovascular Diseases - May 29, 2017 Category: Neurology Source Type: research
Serum 1,5-Anhydroglucitol: Risk Factor of Acute Ischemic Stroke and Transient Ischemic Attack in Well-Controlled Diabetes
Conclusions: Low serum 1,5-AG levels could be a possible marker for AIS/TIA risk in patients with well-controlled DM.Cerebrovasc Dis 2017;44:325 –329
Source: Cerebrovascular Diseases - October 26, 2017 Category: Neurology Source Type: research
Lipid-Lowering Pretreatment and Outcome Following Intravenous Thrombolysis for Acute Ischaemic Stroke: A Post Hoc Analysis of the Enhanced Control of Hypertension and Thrombolysis Stroke Study Trial
Conclusions: Lipid-lowering pretreatment is not associated with adverse outcome in AIS patients treated with intravenous alteplase, whether assessed by 90-day death and disability or death alone.Cerebrovasc Dis 2018;45:213 –220
Source: Cerebrovascular Diseases - April 27, 2018 Category: Neurology Source Type: research
The Impact of Pregnancy on Hemorrhagic Stroke in Young Women
Conclusions: Women with pregnancy-associated HS had fewer cerebrovascular risk factors, lower odds of having underlying vascular lesions, and higher proportion of migraine and RCVS compared with similar-aged non-pregnant women. Pregnancy-associated HS appears to represent a unique pathophysiological process, requiring targeted study.Cerebrovasc Dis 2018;46:10 –15
Source: Cerebrovascular Diseases - July 6, 2018 Category: Neurology Source Type: research
Order of Treatment Matters in Ischemic Stroke: Mechanical Thrombectomy First, Then Carotid Artery Stenting for Tandem Lesions of the Anterior Circulation
Conclusion: Mechanical thrombectomy prior to acute CAS in TO is a predictive factor for favorable clinical outcome at 90 days.Cerebrovasc Dis 2018;46:59 –65
Source: Cerebrovascular Diseases - August 9, 2018 Category: Neurology Source Type: research
Insulin Resistance Index from Oral Glucose Tolerance Test Predicts Ischemic Stroke Outcomes in Non-Diabetic Patients with Different Estimated Glomerular Filtration Rate Strata
Conclusions: An OGTT-derived estimate of insulin resistance with the composite ISI, but not HOMA-IR, was independently associated with increased risks of 1-year mortality and poor functional outcome in non-diabetic ischemic stroke patients with different eGFR strata.Cerebrovasc Dis 2018;46:140 –149
Source: Cerebrovascular Diseases - September 20, 2018 Category: Neurology Source Type: research
Transcranial Magnetic Stimulation as an Intervention Tool to Recover from Language, Swallowing and Attentional Deficits after Stroke: A Systematic Review
Background: Following a stroke event, patients often are severely affected by disabilities that hinder their quality-of-life. There are currently several rehabilitative options and strategies, and it is crucial to find the most effective interventions. The applicability of transcranial magnetic stimulation (TMS) to the recovery of nonmotor functions such as communication skills, swallowing ability and spatial attention after stroke remains important clinical questions.Summary: We searched PubMed and ISI Web of Science for articles that used repetitive TMS protocols to rehabilitate post-stroke deficits. We analysed qualitat...
Source: Cerebrovascular Diseases - October 19, 2018 Category: Neurology Source Type: research
A Systematic Review and Meta-Analysis of Molecular Biomarkers Associated with Early Neurological Deterioration Following Acute Stroke
Background: Early neurological deterioration (END) following acute stroke is associated with poorer long-term outcomes. Identification of patients at risk could assist early monitoring and treatment decisions. This review summarised the evidence describing non-radiological biomarkers for END.Summary: Electronic searches from January 1990 to March 2017 identified studies reporting a blood/cerebrospinal fluid (CSF)/urine biomarker measurement within 24 h of acute stroke and at least 2 serial assessments of clinical neurological status (#x3c; 24 h and #x3c; 7 days). Out of 12,895 citations, 82 studies were included, mostly fo...
Source: Cerebrovascular Diseases - December 5, 2018 Category: Neurology Source Type: research
The Relationship between Blood Pressure Variability, Recanalization Degree, and Clinical Outcome in Large Vessel Occlusive Stroke after an Intra-Arterial Thrombectomy
Conclusions: Short-term BPV over 24 and 48 h after IAT in acute ischemic stroke patients was related to recanalization degree, and END occurrence, and may be an independent predictor of clinical outcome.Cerebrovasc Dis 2018;46:279 –286
Source: Cerebrovascular Diseases - January 15, 2019 Category: Neurology Source Type: research
Sex-Related Differences in Management and Outcome of Acute Ischemic Stroke in Eligible Patients to Thrombolysis
Conclusions: We provided an exhaustive overview and real-life professional practices conditions in thrombolyzed AIS. Despite a later prehospital management in neurovascular units and more severe strokes at admission, women and men had both similar outcomes at hospital discharge and in 3-month survival, but women were associated to worst functional outcome at 3 months.Cerebrovasc Dis
Source: Cerebrovascular Diseases - May 23, 2019 Category: Neurology Source Type: research
Intravenous Thrombolysis Guided by Perfusion CT with Alteplase in & #x3e;4.5 Hours from Stroke Onset
Conclusions: IVT in patients with WUS, SUKO, or stroke beyond #x3e;4.5 h from LSN, with salvageable brain tissue on CTP, seems to be safe and has similar functional outcomes at 90 days to the standard therapeutic window, even when combined with MT.Cerebrovasc Dis
Source: Cerebrovascular Diseases - July 2, 2020 Category: Neurology Source Type: research
