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Source: Cerebrovascular Diseases

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Total 653 results found since Jan 2013.

Independent Predictive Value of Elevated YKL-40 in Ischemic Stroke Prognosis: Findings from a Nationwide Stroke Registry
Conclusions: The elevated YKL-40 at admission can potentially help predict death, functional prognosis after ischemic stroke, which may help further studies to explore the potential physiological and pathological mechanism including the effects of vulnerable plaque and collateral circulation.Cerebrovasc Dis
Source: Cerebrovascular Diseases - January 30, 2023 Category: Neurology Source Type: research

Increased Serum EphrinA1 Is Associated With Parenchymal Hematoma (PH) After Ischemic Stroke
Conclusion Higher serum EphrinA1 is independently associated with higher risk of PH after ischemic stroke. Future studies with larger sa mple size are needed to validate our findings and elucidate the potential role of EphrinA1 in PH.
Source: Cerebrovascular Diseases - April 27, 2023 Category: Neurology Source Type: research

Prevalence of Potential Retrograde Embolization Pathways in the Proximal Descending Aorta in Stroke Patients and Controls
Background: Retrograde diastolic blood flow in the proximal descending aorta (DAo) connecting complex plaques (≥4 mm thick) with brain-supplying supra-aortic arteries may constitute a source of stroke. Yet, data only from high-risk populations (cryptogenic stroke patients with aortic atheroma ≥3 mm) regarding the prevalence of this potential stroke mechanism are available. We aimed to quantify the frequency of this mechanism in unselected patients with cryptogenic stroke after routine diagnostics and controls without a history of stroke. Methods: 88 patients (67 stroke patients, 21 cardiac controls) were prospectively ...
Source: Cerebrovascular Diseases - December 4, 2014 Category: Neurology Source Type: research

Is Prehospital Treatment of Acute Stroke too Expensive? An Economic Evaluation Based on the First Trial
Conclusion: This study indicates that based on a one-year benefit-cost analysis that prehospital treatment of acute stroke is highly cost-effective across a wide range of possible scenarios. It is the highest when the staff size of the Mobile Stroke Unit can be reduced, for example, by the use of telemedical support from hospital experts. Although efficiency is positively related to population density, benefit-cost ratios can be greater than 1 even in rural settings.Cerebrovasc Dis 2014;38:457-463
Source: Cerebrovascular Diseases - December 19, 2014 Category: Neurology Source Type: research

Is Prehospital Treatment of Acute Stroke too Expensive An Economic Evaluation Based on the First Trial
Conclusion: This study indicates that based on a one-year benefit-cost analysis that prehospital treatment of acute stroke is highly cost-effective across a wide range of possible scenarios. It is the highest when the staff size of the Mobile Stroke Unit can be reduced, for example, by the use of telemedical support from hospital experts. Although efficiency is positively related to population density, benefit-cost ratios can be greater than 1 even in rural settings.Cerebrovasc Dis 2014;38:457-463
Source: Cerebrovascular Diseases - December 23, 2014 Category: Neurology Source Type: research

Dynamic Cerebral Autoregulation Is Transiently Impaired for One Week after Large-Vessel Acute Ischemic Stroke
Background: Dynamic cerebral autoregulation (DCA) is the continuous counterregulation of cerebral blood flow to fluctuations in blood pressure. DCA can become impaired after acute stroke, but it remains unclear to what extent and over what interval this occurs. Methods: We included 28 patients (NIHSS = 12 ± 6.5, age = 68.4 ± 17.1, 16F) with acute large-vessel ischemic stroke in the middle cerebral artery territory and 29 healthy controls (mean age 54.9 ± 9, 16F). DCA was assessed by simultaneous measurement of blood pressure together with blood flow velocities using finger plethysmography/arterial catheter and transcran...
Source: Cerebrovascular Diseases - February 3, 2015 Category: Neurology Source Type: research

Post Stroke Pain: Identification, Assessment, and Therapy
Background: Pain is a common complication after stroke and is associated with the presence of depression, cognitive dysfunction, and impaired quality of life. It remains underdiagnosed and undertreated, despite evidence that effective treatment of pain may improve function and quality of life. Summary: We provide an overview of the means for clinical assessment and risk factors for the development of post-stroke pain, then review the newest available literature regarding the commonest post-stroke pain syndromes, including central post-stroke pain, complex regional pain syndrome, musculoskeletal pain including shoulder subl...
Source: Cerebrovascular Diseases - March 5, 2015 Category: Neurology Source Type: research

Serum Vitamin D Status as a Predictor of Prognosis in Patients with Acute Ischemic Stroke
Background: Low 25-hydroxyvitamin D (25(OH)D) concentrations have been shown to predict risk of cardiovascular disease and all-cause mortality. Although the prevalence of 25(OH)D deficiency is high in patients with acute stroke, the prognostic value of 25(OH)D in stroke has not been clearly established. The purpose of this study was to determine whether the baseline serum 25(OH)D level was associated with the functional outcome in patients with acute ischemic stroke. Methods: From June 2011 to January 2014, consecutive patients with acute ischemic stroke within 7 days of symptom onset were enrolled in this study from a pro...
Source: Cerebrovascular Diseases - July 11, 2015 Category: Neurology Source Type: research

Risk of Stroke-Associated Pneumonia and Oral Hygiene
Conclusion: In this large hospital-based cohort of patients admitted with acute stroke, systematic OHC use was associated with decreased odds of hospital-acquired pneumonia.Cerebrovasc Dis 2016;41:35-39
Source: Cerebrovascular Diseases - November 20, 2015 Category: Neurology Source Type: research

ApoE Polymorphisms and the Risk of Different Subtypes of Stroke in the Chinese Population: A Comprehensive Meta-Analysis
Background and Purpose: Numerous studies have evaluated the association between apolipoprotein E (ApoE) gene polymorphisms and the risk of different subtypes of stroke. However, the results remain uncertain, and few sources of data specific to the Chinese ethnic population contribute to these outstanding questions. Therefore, we performed a meta-analysis to derive a more comprehensive estimate of the association between ApoE polymorphisms and stroke risk in the Chinese population. Methods: Case-control studies in Chinese and English publications were identified by searching the PubMed, EMBASE, Web of Science, China Nation ...
Source: Cerebrovascular Diseases - January 12, 2016 Category: Neurology Source Type: research

Observational Study of Obstructive Sleep Apnea in Wake-Up Stroke: The SLEEP TIGHT Study
Conclusions: WUS may be associated with severe OSA with more oxygen desaturation in men but not in women. WUS may be associated with high DBP and increased LDL cholesterol.Cerebrovasc Dis 2016;41:233-241
Source: Cerebrovascular Diseases - January 27, 2016 Category: Neurology Source Type: research

Posterior versus Anterior Circulation Stroke in Young Adults: A Comparative Study of Stroke Aetiologies and Risk Factors in Stroke among Young Fabry Patients (sifap1)
Background: Although 20-30% of all strokes occur in the posterior circulation, few studies have explored the characteristics of patients with strokes in the posterior compared to the anterior circulation so far. Especially data on young patients is missing.Methods: In this secondary analysis of data of the prospective multi-centre European sifap1 study that investigated stroke and transient ischemic attack (TIA) patients aged 18-55 years, we compared vascular risk factors, stroke aetiology, presence of white matter hyperintensities (WMH) and cerebral microbleeds (CMB) between patients with ischaemic posterior circulation s...
Source: Cerebrovascular Diseases - January 13, 2017 Category: Neurology Source Type: research

The Prevalence of and Factors Related to Vascular Hyperintensity on T1-Weighted Imaging in Acute Ischemic Stroke
Conclusion: The T1-HVS was observed in 4.5% of acute ischemic stroke patients. T1-HVSs appeared in the subacute phase in arteries with persistent occlusion and remained for a few months.Cerebrovasc Dis 2017;44:203-209
Source: Cerebrovascular Diseases - August 15, 2017 Category: Neurology Source Type: research

Acute Kidney Injury Following Acute Ischemic Stroke and Intracerebral Hemorrhage: A Meta-Analysis of Prevalence Rate and Mortality Risk
Conclusions: This meta-analysis provides evidence that AKI is a common complication following both AIS and ICH and it is associated with increased mortality following AIS but not ICH. This highlights the need for early assessment of renal function in the acute phase of AIS, in particular, and avoidance of factors than may induce AKI in vulnerable patients.Cerebrovasc Dis 2017;45:1 –9
Source: Cerebrovascular Diseases - November 24, 2017 Category: Neurology Source Type: research