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Source: The American Journal of Chinese Medicine
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Total 70 results found since Jan 2013.
Effects and Mechanistic Role of Mulberry Leaves in Treating Diabetes and its Complications
Am J Chin Med. 2023 Aug 30:1-39. doi: 10.1142/S0192415X23500775. Online ahead of print.ABSTRACTDiabetes mellitus (DM) has become a surge burden worldwide owing to its high prevalence and range of associated complications such as coronary artery disease, blindness, stroke, and renal failure. Accordingly, the treatment and management of DM have become a research hotspot. Mulberry leaves (Morus alba L.) have been used in Traditional Chinese Medicine for a long time, with the first record of its use published in Shennong Bencao Jing (Shennong's Classic of Materia Medica). Mulberry leaves (MLs) are considered highly valuable me...
Source: The American Journal of Chinese Medicine - August 30, 2023 Category: Complementary Medicine Authors: Yanjiao Zhang Runyu Miao Kaile Ma Yuxin Zhang Xinyi Fang Jiahua Wei Ruiyang Yin Jingxue Zhao Jiaxing Tian Source Type: research
Metabolomics Analysis of Electroacupuncture Pretreatment Induced Neuroprotection on Mice with Ischemic Stroke
In conclusion, our study revealed that EA pretreatment may attenuate the ischemic brain injury by inhibiting glycolysis and increasing the levels of some neuroprotective metabolites.PMID:37335209 | DOI:10.1142/S0192415X23500520
Source: The American Journal of Chinese Medicine - June 19, 2023 Category: Complementary Medicine Authors: Su-Hao Yang Xin-Xiao Zhang Zhan-Qiong Zhong Xia-Xia Luo Yu-Fei Wang Xing-Ping Xiao Ze-Qin Huang Si-Yi Yu Jia-Yi Sun Mei-Jun Liu Xiao-Yi Xiong Source Type: research
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury
In conclusion, baicalin could reduce BMECs apoptosis, protect tight junctions, and resist immune cell infiltration, thereby alleviating ischemic stroke. Our findings potentially provide a novel treatment strategy for ischemic stroke.PMID:36661075 | DOI:10.1142/S0192415X23500180
Source: The American Journal of Chinese Medicine - January 20, 2023 Category: Complementary Medicine Authors: Zhiyuan Hao Zheyu Zhang Yuhang Zhao Dongsheng Wang Source Type: research
Ginsenoside Rd Inhibited Ferroptosis to Alleviate CCl < sub > 4 < /sub > -Induced Acute Liver Injury in Mice via cGAS/STING Pathway
In conclusion, our results suggested that ginsenoside Rd inhibited ferroptosis via the cGAS/STING pathway, thereby protecting mice from CCl4-induced ALI. These results suggested ginsenoside Rd may be used as a potential intervention treatment against CCl4-induced ALI.PMID:36437551 | DOI:10.1142/S0192415X23500064
Source: The American Journal of Chinese Medicine - November 28, 2022 Category: Complementary Medicine Authors: Yuangeng Li Ping Yu Wenwen Fu Shuo Wang Wenjun Zhao Yue Ma Yi Wu Heming Cui Xiaofeng Yu Li Fu Huali Xu Dayun Sui Source Type: research
Tanshinone IIA Microemulsion Protects against Cerebral Ischemia Reperfusion Injury via Regulating H3K18ac and H4K8ac < em > In Vivo < /em > and < em > In Vitro < /em >
In this study, we developed microemulsion loaded with TanIIA (TanIIA ME) to break through these limitations, and explored the neuroprotective effect of TanIIA ME against CIRI and the epigenetic regulation mechanism of this neuroprotection. In vivo, middle cerebral artery occlusion (MCAO) models were treated with TanIIA ME and TanIIA solution or sodium valproate as a control. The effect of TanIIA ME on HDAC activity was determined by ELISA assay. In addition, we used primary hippocampal neurons to establish oxygen-glucose deprivation and reoxygenation (OGD/R) models. Lactate dehydrogenase (LDH) assay and terminal deoxynucle...
Source: The American Journal of Chinese Medicine - October 3, 2022 Category: Complementary Medicine Authors: Hui Ma Zeng-Chun Hu Yu Long Li-Chun Cheng Chen-Yang Zhao Ming-Kun Shao Source Type: research
