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126 * extra-anatomic revascularisation for distal occlusion of the left or right common carotid artery in acute type a aortic dissection with cerebral malperfusion
Conclusion: Extra-anatomic bypass for distal LCCA or RCCA occlusion presents a valuable bail-out technique to restore cerebral perfusion during AADA repair, potentially reducing the increased incidence of neurological complications in patients with cerebral malperfusion.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Luehr, M., Etz, C. D., Lehmkuhl, L., Misfeld, M., Bakhtiary, F., Borger, M., Mohr, F. Tags: Complicated type A aortic dissection: Malperfusion and outcome Source Type: research

135 * coronary artery bypass surgery without cardioplegia: early results in 8515 patients
Conclusion: Isolated CABG with CPB using non-cardioplegic methods proved highly secure, with low mortality and morbidity.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Antunes, P. E., Oliveira, J., Prieto, D., Coutinho, G. F., Correia, P., Branco, C. F., Antunes, M. J. Tags: Technical aspects of coronary bypass graft surgery Source Type: research

138 * robotic versus conventional coronary artery bypass graft: a propensity score-based comparison of perioperative and long-term results
Conclusion: In order to achieve endoscopic revascularization with complete sternal stability, longer operative times are needed. Short- and long-term results of robotic coronary surgery are equivalent to conventional sternotomy CABG.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Kofler, M., Stastny, L., Schachner, T., Kilo, J., Grimm, M., Mueller, L., Bonatti, J., Bonaros, N. Tags: Technical aspects of coronary bypass graft surgery Source Type: research

260 * current evidence of coronary artery bypass grafting off-pump versus on-pump: a systematic review with meta-analysis of more than 16,500 patients investigated in 66 randomised controlled trials
Conclusion: The present systematic review emphasises that both strategies, off-pump and on-pump, are suitable alternatives for CABG. The choice for either procedure should be individualised for each single patient with regard to comorbidities, life expectancy, and the surgeon's experience.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Deppe, A. C., Choi, Y., Arbash, W., Kuhn, E. W., Scherner, M., Slottosch, I., Rahmanian, P., Liakopoulos, O. J., Wahlers, T. Tags: Developments in coronary artery bypass graft Source Type: research

264 * results of total arterial versus conventional versus hybrid myocardial revascularisation: a propensity match analysis of long-term follow-up
Conclusion: Total arterial revascularisation provides improved outcomes at mid-term follow-up compared with conventional or hybrid revascularisation. The latter technique is particularly associated with a significantly higher incidence of late myocardial infarction and repeat revascularisation.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Muneretto, C., Repossini, A., Di Bacco, L., Bisleri, G. Tags: Developments in coronary artery bypass graft Source Type: research

313 * effect of carotid revascularisation on cerebral autoregulation in combined cardiac surgery
Conclusion: Patients with uncorrected carotid stenosis have evidence of impaired autoregulation during CPB. In contrast, patients undergoing CEA prior to subsequent cardiac surgery have more preserved cerebral autoregulation.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Ono, M., Hori, D., Adachi, H., Hogue, C. Tags: Cardiac surgery in marginal patients Source Type: research

337 * direct aortic implantation of a self-expanding transcatheter aortic valve leads to favourable outcomes
Conclusion: DA TAVI with the CoreValve System led to favourable early outcomes in patients with prohibitive iliofemoral access.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Bruschi, G., Moat, N. Tags: Late Breakers I Source Type: research

Preoperative atrial fibrillation and outcome in patients undergoing on-pump or off-pump coronary bypass surgery: lessons learned from the GOPCABE trial
CONCLUSIONS AF at admission is a significant risk factor for elderly patients undergoing coronary bypass grafting. However, this risk is not altered by performing bypass grafting off pump.
Source: Interactive CardioVascular and Thoracic Surgery - December 18, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Boning, A., Diegeler, A., Hilker, M., Zacher, M., Reents, W., Faerber, G., Doenst, T., for the GOPCABE investigators Tags: Molecular biology, Myocardial infarction, Myocardial protection, Transplantation - heart Adult Cardiac Source Type: research

The safety of deep hypothermic circulatory arrest in aortic valve replacement with unclampable aorta in non-octogenarians
CONCLUSIONS Postoperative neurological events and operative mortality were, respectively, 3- and 4-fold higher in octogenarians undergoing AVR using DHCA. Such patients may represent suitable candidates for TAVR if favourable outcomes are demonstrated in patients with atherosclerotic aortas. Surgical AVR remains the standard treatment option with excellent outcomes for patients <80 years old with unclampable aortas.
Source: Interactive CardioVascular and Thoracic Surgery - December 18, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Kaneko, T., Neely, R. C., Shekar, P., Javed, Q., Asghar, A., McGurk, S., Gosev, I., Byrne, J. G., Cohn, L. H., Aranki, S. F. Tags: Cerebral protection, Great vessels, Valve disease Adult Cardiac Source Type: research

Should we consider beating-heart on-pump coronary artery bypass grafting over conventional cardioplegic arrest to improve postoperative outcomes in selected patients?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether beating-heart on-pump coronary artery bypass grafting (BH-ONCAB) offered superior mortality and morbidity outcomes when compared with conventional on-pump coronary artery bypass grafting (C-ONCAB). Morbidity outcomes consisted of renal failure, stroke (transient or permanent), myocardial infarction, angina, congestive cardiac failure, reintervention and arrhythmias. Best evidence papers investigating BH-ONCAB versus C-ONCAB were considered. Where data were duplicated, the more credible evidence-based ...
Source: Interactive CardioVascular and Thoracic Surgery - March 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Al Jaaly, E., Chaudhry, U. A. R., Harling, L., Athanasiou, T. Tags: Molecular biology, Myocardial protection Adult Cardiac Source Type: research

Off-pump or on-pump beating heart: which technique offers better outcomes following coronary revascularization?
A best evidence topic was written according to a structured protocol. The question addressed was whether on-pump beating heart coronary artery bypass (BH-ONCAB) surgery has a different outcome profile in comparison to off-pump coronary artery bypass (OPCAB). A total of 205 papers were found by systematic search of which 7 provided the largest and most recent outcome analysis comparing BH-ONCAB with OPCAB, and represented the best evidence to answer the clinical question. The authors, date, journal, study type, population, main outcome measures and results were tabulated. Reported outcome measures included mortality, stroke...
Source: Interactive CardioVascular and Thoracic Surgery - March 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Sepehripour, A. H., Chaudhry, U. A. R., Harling, L., Athanasiou, T. Tags: Molecular biology, Myocardial protection Adult Cardiac Source Type: research

How safe is it to train residents to perform off-pump coronary artery bypass surgery?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, in [patients undergoing off-pump CABG] are [postoperative mortality and morbidity outcomes] acceptable when performed by [trainees]? Altogether more than 597 papers were found using the reported search, of which 8 represented the best evidence to answer the clinical question. Six retrospective cohort studies directly compared the performance of trainees and experienced surgeons in off-pump coronary artery bypass graft surgery. Of the remaining papers, one recorded the performance of trainees in on- and off-p...
Source: Interactive CardioVascular and Thoracic Surgery - April 22, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Smith, T. A., Asimakopoulos, G. Tags: Electrophysiology - arrhythmias, Molecular biology Adult Cardiac Source Type: research

Protective effects of corticosteroids in coronary artery bypass graft surgery alone or combined with valvular surgery: an updated and comprehensive meta-analysis and systematic review
This systematic review with meta-analysis sought to determine the protective effects of corticosteroids on clinical outcomes following coronary artery bypass grafting (CABG). Medline, Embase, Elsevier and Sciences online database as well as Google scholar literature were used for selecting appropriate studies with randomized controlled design. The effect sizes measured were odds ratio (OR) for categorical variables and weighted mean difference with 95% confidence interval (CI) for calculating differences between mean values of duration of hospitalization in intervention and control groups. Values of P < 0.1 for Q-test o...
Source: Interactive CardioVascular and Thoracic Surgery - May 28, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Ali-Hassan-Sayegh, S., Mirhosseini, S. J., Haddad, F., Karimi-bondarabadi, A. A., Shahidzadeh, A., Weymann, A., Popov, A.-F., Sabashnikov, A. Tags: Cardiac - pharmacology, Coronary disease Adult Cardiac Source Type: research

Safety and efficacy of glucose-insulin-potassium treatment in coronary artery bypass graft surgery and percutaneous coronary intervention
The purpose of this meta-analysis was to evaluate protective effects of glucose–insulin–potassium (GIK) on outcomes after coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). We systematically searched Medline/Pubmed, Elsevier, Embase, Web of Knowledge and Google Scholar. A total of 1206 studies were retrieved during the extensive literature search of all major databases; however, 38 trials reporting the end-point of interest were selected. We performed a pooled analysis of outcomes following PCI: incidence of cardiac arrest [odds ratio (OR) of 0.91; 95% confidence interval (CI): ...
Source: Interactive CardioVascular and Thoracic Surgery - October 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Ali-Hassan-Sayegh, S., Mirhosseini, S. J., Zeriouh, M., Dehghan, A. M., Shahidzadeh, A., Karimi-Bondarabadi, A. A., Sabashnikov, A., Popov, A.-F. Tags: Congestive Heart Failure Adult Cardiac Source Type: research

How revascularization on the beating heart with cardiopulmonary bypass compares to off-pump? A meta-analysis of observational studies
Off-pump coronary artery bypass surgery has been a controversial area of debate and the outcome profile of the technique has been thoroughly investigated. Scepticism regarding the reported outcomes and the conduct of the randomized trials comparing this technique with conventional on-pump coronary artery bypass surgery has been widely voiced, and the technique of off-pump surgery remains as an infrequently adopted approach to myocardial revascularization worldwide. Criticisms of the technique are related to lower rates of complete revascularization and its unknown long-term consequences, the significant detrimental effects...
Source: Interactive CardioVascular and Thoracic Surgery - December 26, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Sepehripour, A. H., Chaudhry, U. A., Suliman, A., Kidher, E., Sayani, N., Ashrafian, H., Harling, L., Athanasiou, T. Tags: Education, Molecular biology, Myocardial protection Adult Cardiac Source Type: research

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