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Source: EurekAlert! - Biology
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Total 109 results found since Jan 2013.
Study finds long-term survival of human neural stem cells transplanted into primate brain
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Human neural stem cells (hNSCs) labeled with magnetic nanoparticles were followed by MRI after transplantation into the brains of primates. The study evaluated the long-term survival and differentiation of hNSCs. The hNSCs differentiated into neurons at 24 months and did not cause tumors. Researchers concluded that hNSCs could be of great value as a source for cell replacement and gene transfer for treating Parkinson's disease, Huntington's disease, Alzheimer's disease, ALS, spinal cord injury and stroke.
Source: EurekAlert! - Biology - April 23, 2014 Category: Biology Source Type: news
Preliminary results show improvement in MS symptoms
(NIH/National Institute of Neurological Disorders and Stroke) Combining the estrogen hormone estriol with Copaxone, a drug indicated for the treatment of patients with relapsing forms of multiple sclerosis, may improve symptoms in patients with the disorder, according to preliminary results from a clinical study of 158 patients with relapsing remitting multiple sclerosis. The findings were presented today by Rhonda Voskuhl, M.D., from the University of California, Los Angeles, at the American Academy of Neurology Annual Meeting in Philadelphia.
Source: EurekAlert! - Biology - April 29, 2014 Category: Biology Source Type: news
Stem cells from teeth can make brain-like cells
(University of Adelaide) University of Adelaide researchers have discovered that stem cells taken from teeth can grow to resemble brain cells, suggesting they could one day be used in the brain as a therapy for stroke.
Source: EurekAlert! - Biology - April 30, 2014 Category: Biology Source Type: news
Longevity gene may boost brain power
(NIH/National Institute of Neurological Disorders and Stroke) Scientists showed that people who have a variant of a longevity gene, called KLOTHO, have improved brain skills such as thinking, learning and memory regardless of their age, sex, or whether they have a genetic risk factor for Alzheimer's disease. Increasing KLOTHO gene levels in mice made them smarter, possibly by increasing the strength of connections between nerve cells in the brain. The study was partly funded by the National Institutes of Health.
Source: EurekAlert! - Biology - May 9, 2014 Category: Biology Source Type: news
NIH scientists take totally tubular journey through brain cells
(NIH/National Institute of Neurological Disorders and Stroke) Scientists at the National Institutes of Health took a molecular-level journey into microtubules, the hollow cylinders inside brain cells that act as skeletons and internal highways, and watched how a protein called tubulin acetyltransferase (TAT) labels the inside of microtubules. The results answer long-standing questions about how TAT tagging works and offer clues as to why it is important for brain health.
Source: EurekAlert! - Biology - June 13, 2014 Category: Biology Source Type: news
Scientists use lasers to control mouse brain switchboard
(NIH/National Institute of Neurological Disorders and Stroke) Using mice and flashes of light, scientists show that just a few nerve cells in the brain may control the switch between internal thoughts and external distractions. The study may be a breakthrough in understanding how a critical part of the brain, called the thalamic reticular nucleus, influences consciousness.
Source: EurekAlert! - Biology - August 14, 2014 Category: Biology Source Type: news
TSRI scientists create mimic of 'good' cholesterol to fight heart disease and stroke
(Scripps Research Institute) Scientists at The Scripps Research Institute have created a synthetic molecule that mimics 'good' cholesterol and have shown it can reduce plaque buildup in the arteries of animal models. The molecule, taken orally, improved cholesterol in just two weeks. The research points scientists toward a new method for treating atherosclerosis, a condition where plaque buildup in the arteries can cause heart attacks and strokes.
Source: EurekAlert! - Biology - October 9, 2014 Category: Biology Source Type: news
NIH-funded research lays groundwork for next-generation prosthetics
(NIH/National Institute of Neurological Disorders and Stroke) Three groups of researchers who have received support from the National Institutes of Health will obtain funding from the President's BRAIN Initiative to improve artificial limb technology. The new awards will be funded and administered by the Defense Advanced Research Projects Agency and will build on the fundamental discoveries that were made possible by National Institute of Health support.
Source: EurekAlert! - Biology - February 9, 2015 Category: Biology Source Type: news
Study reveals how genetic changes lead to familial Alzheimer's disease
(NIH/National Institute of Neurological Disorders and Stroke) Mutations in the presenilin-1 gene are the most common cause of inherited, early-onset forms of Alzheimer's disease. In a new study, published in Neuron, scientists replaced the normal mouse presenilin-1 gene with Alzheimer's-causing forms of the human gene to discover how these genetic changes may lead to the disorder. Their surprising results may transform the way scientists design drugs that target these mutations to treat inherited or familial Alzheimer's, a rare form of the disease.
Source: EurekAlert! - Biology - March 11, 2015 Category: Biology Source Type: news
Scientists unravel the mystery of the tubulin code
(NIH/National Institute of Neurological Disorders and Stroke) Driving down the highway, you encounter ever-changing signs -- speed limits, exits, food and gas options. Seeing these roadside markers may cause you to slow down, change lanes or start thinking about lunch. In a similar way, cellular structures called microtubules are tagged with a variety of chemical markers that can influence cell functions. The pattern of these markers makes up the 'tubulin code' and scientists have uncovered the mechanism behind one of the main writers of this code.
Source: EurekAlert! - Biology - May 12, 2015 Category: Biology Source Type: news
Scientists manipulate consciousness in rats
(NIH/National Institute of Neurological Disorders and Stroke) Scientists showed that they could alter brain activity of rats and either wake them up or put them in an unconscious state by changing the firing rates of neurons in the central thalamus, a region known to regulate arousal. The study, published in eLIFE, was partially funded by the National Institutes of Health.
Source: EurekAlert! - Biology - December 17, 2015 Category: Biology Source Type: news
Vascular surgery research brings new options to high-risk stroke patients
(Minneapolis Heart Institute Foundation) More than 300,000 Americans are diagnosed annually with blockages of the carotid artery. The FDA recently approved a new Transcarotid Artery Revascularization procedure utilizing the ENROUTE® Transcarotid Neuroprotection and Stent System from Silk Road Medical. The Minneapolis Heart Institute Foundation® was selected to participate in the study of the stent system. Jessica Titus, M.D., and Timothy Sullivan, M.D., vascular surgeons at the Minneapolis Heart Institute® at Abbott Northwestern Hospital, will serve as principal trial investigators.
Source: EurekAlert! - Biology - January 15, 2016 Category: Biology Source Type: news
Scientists win $1.7 million grant to advance new strategies to treat Huntington's disease
(Scripps Research Institute) Scientists from the Florida campus of The Scripps Research Institute have won nearly $1.7 million from the National Institutes of Health's National Institute of Neurological Disorders and Stroke to investigate the mechanisms that contribute to Huntington's disease, a fatal inherited disease that some have described as having ALS, Parkinson's and Alzheimer's -- at the same time.
Source: EurekAlert! - Biology - February 12, 2016 Category: Biology Source Type: news
Low levels of two components of vitamin D can help predict risk of heart attack
(Intermountain Medical Center) Low levels of total vitamin D and bioavailable vitamin D can help predict a person's risk of major adverse cardiovascular events such as a heart attack, stroke, heart failure or death, according to a first-of-its-kind study from the Intermountain Medical Center Heart Institute in Salt Lake City.
Source: EurekAlert! - Biology - April 2, 2016 Category: Biology Source Type: news
Leg-wing coordination may be key transition in origin of flight for baby birds, dinosaurs
(PLOS) Hi-res X-ray movies reveal that despite having extremely underdeveloped muscles and wings, young birds may acquire a mature flight stroke early in development by initially relying more on their legs and wings for power, according to a study published April 21, 2016 in the open-access journal PLOS ONE.
Source: EurekAlert! - Biology - April 21, 2016 Category: Biology Source Type: news
