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The presence of Tau protein in blood as a potential prognostic factor in stroke patients.
Abstract Tau protein is found in the blood of 40 - 50% of patients in the acute phase of a stroke, as a result of the degradation of neurons and damage to the blood-brain barrier. The aim of the study was to assess the incidence of tau protein in the blood of stroke patients, as well as to evaluate the potential impact of tau protein presence in the blood of patients on their neurological state during the first 24 hours, and their functional condition three months after the stroke. Eighty-seven patients aged 39 - 99 (42 females and 45 males) diagnosed with stroke were enrolled in the prospective study (August 2014...
Source: J Physiol Pharmacol - September 30, 2016 Category: Drugs & Pharmacology Authors: A Lasek-Bal A, Jedrzejowska-Szypulka H, Rozycka J, Bal W, Kowalczyk A, Holecki M, Dulawa J, Lewin-Kowalik J Tags: J Physiol Pharmacol Source Type: research

A study of microRNA-223 in evaluating platelet reactivity in patients with acute ischemic stroke
J Physiol Pharmacol. 2022 Feb;73(1). doi: 10.26402/jpp.2022.1.11. Epub 2022 Jul 4.ABSTRACTTo investigate the relationship between plasma microRNA-223 expression and platelet reactivity in patients with acute ischemic stroke (AIS) and to evaluate its predictive value in clopidogrel resistance or high on-treatment platelet reactivity (HTPR). A total of 120 patients with acute ischemic stroke were screened in this study, and 60 patients were included in the acute ischemic stroke group according to the inclusion criteria and platelet reactivity after clopidogrel treatment. control group was 60 non-ischemic stroke patients hosp...
Source: J Physiol Pharmacol - July 6, 2022 Category: Drugs & Pharmacology Authors: D-L Wang X Li R-N Wang Y Sun X-S Xia W-J Tian L Wang Source Type: research

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