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Pressure and Pipes: from neuroimaging to virtual measurement
This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - January 1, 2018 Category: Neurology Authors: Marialuisa Zedde, Rosario Pascarella Tags: Editorials Source Type: research

Translesional pressure gradient and leptomeningeal collateral status in symptomatic middle cerebral artery stenosis
ConclusionsOur study suggested a correlation between translesional pressure gradient and maturation of leptomeningeal collaterals in intracranial atherosclerotic disease. Further studies with more exquisite and dynamic monitoring of cerebral hemodynamics and LMC evolution are needed to verify the current findings.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - November 24, 2017 Category: Neurology Authors: Xinyi Leng, Linfang Lan, Hing Lung Ip, Florence Fan, Sze Ho Ma, Karen Ma, Haipeng Liu, Zhengzheng Yan, Jia Liu, Jill Abrigo, Yannie OY Soo, David S Liebeskind, Ka Sing Wong, Thomas W Leung Tags: Original Article Source Type: research

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis – endorsed by the European Academy of Neurology
ConclusionsMulticentre observational and experimental studies are needed to increase the level of evidence supporting recommendations on the diagnosis and management of CVT.
Source: European Journal of Neurology - August 20, 2017 Category: Neurology Authors: J. M. Ferro, M. ‐G. Bousser, P. Canhão, J. M. Coutinho, I. Crassard, F. Dentali, M. Minno, A. Maino, I. Martinelli, F. Masuhr, D. Aguiar de Sousa, J. Stam, Tags: Guidelines Source Type: research

Utility of digital subtraction angiography ‐based collateral evaluation in medically treated acute symptomatic basilar artery stenosis
ConclusionsThe DSA‐based collateral scoring of the BA large branches might predict long‐term outcome in medically treated symptomatic basilar artery stenosis with mild initial severity. Evaluation of BA collateral perfusion status might be useful to determine appropriate treatment strategies.
Source: European Journal of Neurology - July 14, 2017 Category: Neurology Authors: W. ‐J. Lee, K.‐H. Jung, Y. J. Ryu, J.‐M. Kim, S.‐T. Lee, K. Chu, M. Kim, S. K. Lee, J.‐K. Roh Tags: Original Article Source Type: research

Stroke etiology and collaterals: atheroembolic strokes have greater collateral recruitment than cardioembolic strokes
ConclusionsAtheroembolic strokes seem to be associated with better collateral flow compared to cardioembolic strokes. This may in part explain the worse outcomes of AF‐related stroke.
Source: European Journal of Neurology - April 21, 2017 Category: Neurology Authors: L. C. Rebello, M. Bouslama, D. C. Haussen, J. A. Grossberg, S. Dehkharghani, A. Anderson, S. R. Belagaje, N. A. Bianchi, M. Grigoryan, M. R. Frankel, R. G. Nogueira Tags: Original Article Source Type: research

Added value of multimodal computed tomography imaging: analysis of 1994 acute ischaemic strokes
ConclusionOur study shows an association of MCTI use with lower adjusted 12‐month mortality, better identification of the stroke mechanism and no signs of harm.
Source: European Journal of Neurology - October 31, 2016 Category: Neurology Authors: O. Bill, M. Faouzi, R. Meuli, P. Maeder, M. Wintermark, P. Michel Tags: Original Article Source Type: research

Impact of ASPECTS on computed tomography angiography source images on outcome after thrombolysis or endovascular therapy in large vessel occlusions
ConclusionPatients with extensive early ischaemic changes on CT scans (SI‐ ASPECTS ≤5) might not profit from ET. The impact of ET on outcome in patients with moderately favorable SI‐ASPECTS should be addressed in further trials.
Source: European Journal of Neurology - June 30, 2016 Category: Neurology Authors: K. Wasser, P. Papanagiotou, F. Brunner, H. Hildebrandt, M. Winterhalter, C. Roth, A. Kastrup Tags: Original Article Source Type: research

Impact of thrombolysis in acute ischaemic stroke without occlusion: an observational comparative study
ConclusionsOur study suggests that AIS patients without visible arterial occlusion treated with IV‐rtPA may have no better outcome at 3 months than those untreated. However, only a randomized controlled trial would provide a definitive answer about the impact of rtPA in acute stroke patients without occlusion. Until then, these patients should be treated by rtPA as recommended.
Source: European Journal of Neurology - May 25, 2016 Category: Neurology Authors: N. Ajili, J. P. Decroix, C. Preda, J. Labreuche, D. Lopez, Y. Bejot, P. Michel, M. Sévin‐Allouet, I. Sibon, S. Vergnet, A. Wang, N. Sanda, M. Mazighi, F. Bourdain, B. Lapergue Tags: Original Article Source Type: research

The syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis mimicking an acute stroke
ConclusionsThe decision to thrombolyse or perform an LP in HaNDL patients mimicking a stroke is difficult in the acute setting. Perfusion CT can provide misleading results and CTA may be useful in ruling out occlusion of a cerebral vessel.
Source: European Journal of Neurology - April 22, 2016 Category: Neurology Authors: M. Guillan, A. DeFelipe‐Mimbrera, A. Alonso‐Canovas, M. C. Matute, R. Vera, A. Cruz‐Culebras, N. Garcia‐Barragan, J. Masjuan Tags: Original Article Source Type: research

Neurothrombectomy in acute ischaemic stroke: a prospective single‐centre study and comparison with randomized controlled trials
ConclusionBy choosing pragmatic inclusion criteria state‐of‐the‐art IA therapy of a specialized tertiary stroke centre can be safely applied under real‐world conditions to a higher percentage of patients with similar success to the recently published RCTs.
Source: European Journal of Neurology - February 1, 2016 Category: Neurology Authors: O. Nikoubashman, M. Jungbluth, K. Schürmann, M. Müller, B. Falkenburger, S. C. Tauber, M. Wiesmann, J. B. Schulz, A. Reich Tags: Original Article Source Type: research

Extensive blooming artifact predicts no recanalization after intravenous thrombolysis
ConclusionsThe extent of SVS width beyond the lumen might reflect the content of hemosiderin. An extreme overestimation ratio might indicate aged thrombus, which may be resistant to thrombolysis.
Source: European Journal of Neurology - December 26, 2015 Category: Neurology Authors: S. Yan, Q. Chen, X. Zhang, M. Xu, Q. Han, A. Shao, D. S. Liebeskind, M. Lou Tags: Original Article Source Type: research

Radiological imaging in acute ischaemic stroke
Patients who suffer acute ischaemic stroke can be treated with thrombolysis if therapy is initiated early. Radiological evaluation of the intracranial tissue before such therapy can be given is mandatory. In this review current radiological diagnostic strategies are discussed for this patient group. Beyond non‐enhanced computed tomography (CT), the standard imaging method for many years, more sophisticated CT stroke protocols including CT angiography and CT perfusion have been developed, and additionally an increasing number of patients are examined with magnetic resonance imaging as the first imaging method used. Advant...
Source: European Journal of Neurology - November 13, 2015 Category: Neurology Authors: K. D. Kurz, G. Ringstad, A. Odland, R. Advani, E. Farbu, M. W. Kurz Tags: Review Article Source Type: research

The relationship between the pre‐admission CHA2DS2‐VASc score and proximal artery occlusion in patients with acute stroke and atrial fibrillation
ConclusionThe CHA2DS2‐VASc score was associated with PAO in acute ischaemic stroke patients with AF. The CHA2DS2‐VASc score may be correlated with the NIHSS score through the presence of PAO and with poor functional outcome independently of PAO.
Source: European Journal of Neurology - April 10, 2015 Category: Neurology Authors: Y. Sakamoto, S. Sato, Y. Hama, K. Nagatsuka, K. Minematsu, K. Toyoda Tags: Original Article Source Type: research

Symptomatic intracranial haemorrhage after thrombolysis with adjuvant anticoagulation in basilar artery occlusion
ConclusionsThe risk of sICH was largely determined by extension of ischaemic changes on admission computed tomography. Clinically relevantly, also higher post‐thrombolytic SBP as described earlier and lower perithrombolytic platelet counts do increase the risk, a finding requiring confirmation in other patient series.
Source: European Journal of Neurology - December 1, 2014 Category: Neurology Authors: T. Sairanen, D. Strbian, R. Ruuskanen, H. Silvennoinen, O. Salonen, P. J. Lindsberg Tags: Original Article Source Type: research

Evaluation of the recombinant tissue plasminogen activator pretreatment in acute stroke patients with large vessel occlusions treated with the direct bridging approach. Is it worth the effort?
ConclusionsIntravenous thrombolysis pretreatment in the context of the bridging approach contributes substantially to revascularization.
Source: European Journal of Neurology - September 25, 2014 Category: Neurology Authors: L. Fjetland, K. D. Kurz, S. Roy, M. W. Kurz Tags: Original Article Source Type: research

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