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Specialty: Neurology
Source: Epilepsy Curr

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Total 2303 results found since Jan 2013.

Assisted reproductive technology outcomes and management considerations for people with epilepsy
Curr Opin Endocrinol Diabetes Obes. 2023 Sep 22. doi: 10.1097/MED.0000000000000838. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Epilepsy is a common neurologic condition amongst people with reproductive capacity, and assisted reproductive technology (ART) is being increasingly utilized. A recent population-based study described favorable outcomes of ART in this population, but other work shows how fluctuating sex hormones may influence medication concentrations and seizures.RECENT FINDINGS: This review discusses hormonal influences on epilepsy and catamenial epilepsy, considerations regarding fertility in women with e...
Source: Epilepsy Curr - September 21, 2023 Category: Neurology Authors: Regan J Lemley Paula Emanuela Voinescu Source Type: research

Role of S100 and YKL40 on Intraventricular Cerebral Hemorrhages in the Preterm Infant and the Neuroprotective Role of miR-138-siRNAs-HIF-1a and miR-21-siRNAs-HVCN1 in Neonatal Mice with Nerve Injury
CONCLUSION: Our findings demonstrate that miR-138-siRNAs-HIF-1a and miR-21-siRNAs-HVCN1 injections prevent cerebral ischemia-induced brain damage in hypoxia mice by increasing HVCN1 and HIF-1a and decreasing S100b, which in turn lessens apoptosis and epilepsy in hypoxic mice.PMID:37724672 | DOI:10.2174/0929867331666230915103147
Source: Epilepsy Curr - September 19, 2023 Category: Neurology Authors: Roghayeh Ijabi Zachary A Kaminsky Parisa Roozehdar Janat Ijabi Hemen Moradi-Sardareh King Hwa Ling Najmeh Tehranian Source Type: research

Are Genetic Therapies for Epilepsy Ready for the Clinic?
This article provides an overview of the current state of preclinical studies that show potential for clinical translation. Specifically, we focus on genetic therapies that have demonstrated a clear effect on seizures in animal models and have the potential to be translated to clinical settings. Both therapies targeting the cause of the disease and those that treat symptoms are discussed. We believe that the next few years will be crucial in determining the potential of genetic therapies for treating patients with epilepsy.PMID:37662470 | PMC:PMC10470096 | DOI:10.1177/15357597231176234
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: James S Street Yichen Qiu Gabriele Lignani Source Type: research

Making Up Missed Anti-Seizure Medication Doses: Double or Nothing?
Epilepsy Curr. 2023 Apr 27;23(4):220-221. doi: 10.1177/15357597231169414. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662469 | PMC:PMC10470109 | DOI:10.1177/15357597231169414
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Samuel W Terman Source Type: research

Start Low and Go Slow: The General Principle of Managing Older Adults With Epilepsy Finds Robust Support From Frailty
Epilepsy Curr. 2023 May 28;23(4):235-237. doi: 10.1177/15357597231178072. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662468 | PMC:PMC10470102 | DOI:10.1177/15357597231178072
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Vineet Punia Source Type: research

Depression and Epilepsy: The Bidirectional Relation Goes On and On …
Epilepsy Curr. 2023 Apr 27;23(4):222-224. doi: 10.1177/15357597231169553. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662467 | PMC:PMC10470106 | DOI:10.1177/15357597231169553
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Heidi M Munger Clary Source Type: research

Be a PEACH and Hand Me That Levetiracetam: Seizure Prophylaxis for Spontaneous Intracerebral Hemorrhage
Epilepsy Curr. 2023 May 15;23(4):241-243. doi: 10.1177/15357597231174112. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662466 | PMC:PMC10470104 | DOI:10.1177/15357597231174112
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Mackenzie C Cervenka Source Type: research

Neuronal Physiology of Generalized Seizures: The 4 Horsemen of Absence Epilepsy
Epilepsy Curr. 2023 May 29;23(4):262-264. doi: 10.1177/15357597231172322. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662465 | PMC:PMC10470100 | DOI:10.1177/15357597231172322
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Martin J Gallagher Source Type: research

KIF4 Gene Variant's Disruption of PARP1 Signaling Increases Anxiety and Seizure Susceptibility
Epilepsy Curr. 2023 May 22;23(4):257-258. doi: 10.1177/15357597231175007. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662464 | PMC:PMC10470092 | DOI:10.1177/15357597231175007
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Angelique Bordey Source Type: research

Networks Inhibited and Networks Excited: Loss of Consciousness in Epilepsy
Epilepsy Curr. 2023 Apr 12;23(4):217-219. doi: 10.1177/15357597231166203. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662463 | PMC:PMC10470105 | DOI:10.1177/15357597231166203
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Dario J Englot Source Type: research

Dobbs Versus Jackson: Epilepsy, Reproductive Health, and Abortion
Epilepsy Curr. 2023 May 28;23(4):211-216. doi: 10.1177/15357597231176330. eCollection 2023 Jul-Aug.ABSTRACTOn June 24, 2022, Dobbs vs Jackson Women's Health Organization was decided by the Supreme Court effectively overturning the former precedent of Roe v. Wade. This ruling has direct consequences for the care of persons with epilepsy of childbearing potential. Now more than ever we need to provide informed and comprehensive care to our patients with epilepsy who are particularly vulnerable to the impact of this legislation on their reproductive decision-making. Important areas to understand include (1) the current state ...
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Sarah Weatherspoon Anne Davis Mark Keezer Deepti Zutshi Alison Pack Source Type: research

Slow Down and Seize: Seizures Triggered by Slow Wave Oscillations in a GABAergic Model of Dravet Syndrome
Epilepsy Curr. 2023 May 9;23(4):254-256. doi: 10.1177/15357597231174111. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662461 | PMC:PMC10470107 | DOI:10.1177/15357597231174111
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Gordon F Buchanan Source Type: research

Watch Out for GATORs: Fasting, Seizures, and Nutrient Sensing
Epilepsy Curr. 2023 May 22;23(4):260-261. doi: 10.1177/15357597231176342. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662460 | PMC:PMC10470103 | DOI:10.1177/15357597231176342
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Cameron S Metcalf Source Type: research

P2X7 Forges Ahead in Neonatal Hypoxia
Epilepsy Curr. 2023 May 5;23(4):251-253. doi: 10.1177/15357597231172324. eCollection 2023 Jul-Aug.NO ABSTRACTPMID:37662459 | PMC:PMC10470097 | DOI:10.1177/15357597231172324
Source: Epilepsy Curr - September 4, 2023 Category: Neurology Authors: Ray Dingledine Source Type: research